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Mostrati risultati da 1 a 20 di 117
Titolo Data di pubblicazione Autori Rivista Serie Titolo libro
Switching the three-component Biginelli-like reaction conditions for the regioselective synthesis of new 2-amino[1,2,4]triazolo[1,5-a]pyrimidines 2024 Bonomini, AnnaBertagnin, ChiaraLoregian, Arianna + ORGANIC & BIOMOLECULAR CHEMISTRY - -
Human neural progenitor cell models to study the antiviral effects and neuroprotective potential of approved and investigational human cytomegalovirus inhibitors 2024 Trevisan M.Apolloni L.Mercorelli B.Loregian A. + ANTIVIRAL RESEARCH - -
Design, Synthesis, and Biological Evaluation of Trisubstituted Piperazine Derivatives as Noncovalent Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease Inhibitors with Improved Antiviral Activity and Favorable Druggability 2023 Mercorelli B.Loregian A. + JOURNAL OF MEDICINAL CHEMISTRY - -
A novel N-heterocycles substituted oseltamivir derivatives as potent inhibitors of influenza virus neuraminidase: discovery, synthesis and biological evaluation 2023 Bertagnin C.Bonomini A.Loregian A. + JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY - -
A small molecule targeting the interaction between human papillomavirus E7 oncoprotein and cellular phosphatase PTPN14 exerts antitumoral activity in cervical cancer cells 2023 Bertagnin C.Celegato M.Sturlese M.Mercorelli B.Moro S.Loregian A. + CANCER LETTERS - -
Discovery of N-substituted oseltamivir derivatives as novel neuraminidase inhibitors with improved drug resistance profiles and favorable drug-like properties 2023 Bonomini A.Lucca C.Bertagnin C.Loregian A. + EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - -
Small-Molecule Inhibitor of Flaviviral NS3-NS5 Interaction with Broad-Spectrum Activity and Efficacy In Vivo 2023 Celegato M.Sturlese M.Trevisan M.Favaro A.Moro S.Loregian A.Mercorelli B. + MBIO - -
IN VITRO ANTIVIRAL ACTIVITY OF EPIGALLOCATECHIN GALLATE AGAINST RABIES VIRUS 2023 D. PasqualA. LoregianC. Salata - - Abstract Book
Contemporary medicinal chemistry strategies for the discovery and optimization of influenza inhibitors targeting vRNP constituent proteins 2022 Loregian A. + ACTA PHARMACEUTICA SINICA B - -
Targeted disruption of e6/p53 binding exerts broad activity and synergism with paclitaxel and topotecan against hpv-transformed cancer cells 2022 Celegato M.Messa L.Bertagnin C.Mercorelli B.Loregian A. CANCERS - -
Discovery of novel SARS-CoV-2 inhibitors targeting the main protease Mpro by virtual screenings and hit optimization 2022 Mercorelli, BeatriceDesantis, JennyCelegato, MartaBazzacco, AlessandroLoregian, Arianna + ANTIVIRAL RESEARCH - -
Iterative Optimization and Structure-Activity Relationship Studies of Oseltamivir Amino Derivatives as Potent and Selective Neuraminidase Inhibitors via Targeting 150-Cavity 2022 Bonomini, AnnaBertagnin, ChiaraLoregian, Arianna + JOURNAL OF MEDICINAL CHEMISTRY - -
HPV-induced cancers: preclinical therapeutic advancements 2022 Messa L.Loregian A. EXPERT OPINION ON INVESTIGATIONAL DRUGS - -
Discovery of Novel Boron-Containing N-Substituted Oseltamivir Derivatives as Anti-Influenza A Virus Agents for Overcoming N1-H274Y Oseltamivir-Resistant 2022 Bertagnin, ChiaraBonomini, AnnaLoregian, Arianna + MOLECULES - -
Discovery of highly potent and selective influenza virus neuraminidase inhibitors targeting 150-cavity 2021 Bertagnin C.Loregian A. + EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - -
The antifungal drug isavuconazole inhibits the replication of human cytomegalovirus (HCMV) and acts synergistically with anti-HCMV drugs 2021 Mercorelli B.Celegato M.Gribaudo G.Loregian A. + ANTIVIRAL RESEARCH - -
Identification of C5-NH2 Modified Oseltamivir Derivatives as Novel Influenza Neuraminidase Inhibitors with Highly Improved Antiviral Activities and Favorable Druggability 2021 Bertagnin C.Loregian A. + JOURNAL OF MEDICINAL CHEMISTRY - -
The dimeric form of hpv16 e6 is crucial to drive yap/taz upregulation through the targeting of hscrib 2021 Messa L.Celegato M.Bertagnin C.Mercorelli B.Alvisi G.Palu G.Loregian A. + CANCERS - -
1,2,4-Triazolo[1,5-a]pyrimidines: Efficient one-step synthesis and functionalization as influenza polymerase PA-PB1 interaction disruptors 2021 Bertagnin C.Bonomini A.Loregian A. + EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - -
Author Correction: Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo’ (Nature, (2020), 584, 7821, (425-429), 10.1038/s41586-020-2488-1) 2021 Lavezzo E.Franchin E.Barzon L.Del Vecchio C.Manganelli R.Loregian A.Navarin N.Abate D.Sciro M.Merigliano S.Saluzzo F.Onelia F.Pacenti M.Parisi S. G.Flor L.Cocchio S.Masi G.Sperduti A.Salvador R.Nieddu E.Labella B.Fava L.Brazzale A. R.Toppo S.Trevisan M.Baldo V.Crisanti A. + NATURE - -
Mostrati risultati da 1 a 20 di 117
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