Sfoglia per Autore
Preparation of Cerebellum Granule Neurons from Mouse or Rat Pups and Evaluation of Clostridial Neurotoxin Activity and Their Inhibitors by Western Blot and Immunohistochemistry
2018 Tehran, Domenico Azarnia; Pirazzini, Marco
Hsp90 is involved in the entry of clostridial neurotoxins into the cytosol of nerve terminals
2017 AZARNIA TEHRAN, Domenico; Pirazzini, Marco; Leka, Oneda; Mattarei, Andrea; Lista, Florigio; Binz, Thomas; Rossetto, Ornella; Montecucco, Cesare
Hsp90 and Thioredoxin-Thioredoxin Reductase enable the catalytic activity of Clostridial neurotoxins inside nerve terminals
2017 Pirazzini, Marco; Azarnia Tehran, Domenico; Zanetti, Giulia; Rossetto, Ornella; Montecucco, Cesare
Novel insights into botulinum neurotoxins mechanism of action and the discovery of prophylactic inhibitors against botulism
2016 Azarnia Tehran, Domenico
The first non Clostridial botulinum-like toxin cleaves VAMP within the juxtamembrane domain
2016 Zornetta, Irene; AZARNIA TEHRAN, Domenico; Arrigoni, Giorgio; Anniballi, Fabrizio; Bano, Luca; Leka, Oneda; Zanotti, Giuseppe; Binz, Thomas; Montecucco, Cesare
Inhibition of botulinum neurotoxins interchain disulfide bond reduction prevents the peripheral neuroparalysis of botulism
2015 Zanetti, Giulia; Azarnia Tehran, Domenico; Pirazzini, Marcon; Binz, Thomas; Shone, Clifford C.; Fillo, Silvia; Lista, Florigio; Rossetto, Ornella; Montecucco, Cesare
A novel inhibitor prevents the peripheral neuroparalysis of Botulinum neurotoxins
2015 AZARNIA TEHRAN, Domenico; Zanetti, Giulia; Leka, Oneda; Lista, Florigio; Fillo, Silvia; Binz, Thomas; Shone, Clifford C.; Rossetto, Ornella; Montecucco, Cesare; Paradisi, Cristina; Mattarei, Andrea; Pirazzini, Marco
The thioredoxin reductase - Thioredoxin redox system cleaves the interchain disulphide bond of botulinum neurotoxins on the cytosolic surface of synaptic vesicles
2015 Pirazzini, Marco; Tehran, Domenico Azarnia; Zanetti, Giulia; Lista, Florigio; Binz, Thomas; Shone, Clifford C.; Rossetto, Ornella; Montecucco, Cesare
Thioredoxin and its reductase are present on synaptic vesicles, and their inhibition prevents the paralysis induced by botulinum neurotoxins
2014 Pirazzini, Marco; Tehran, Domenico Azarnia; Zanetti, Giulia; Megighian, Aram; Scorzeto, Michele; Fillo, Silvia; Shone, Clifford C.; Binz, Thomas; Rossetto, Ornella; Lista, Florigio; Montecucco, Cesare
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