Sfoglia per Autore
Apoptotic cell death in disease—Current understanding of the NCCD 2023
2023 Vitale, I.; Pietrocola, F.; Guilbaud, E.; Aaronson, S. A.; Abrams, J. M.; Adam, D.; Agostini, M.; Agostinis, P.; Alnemri, E. S.; Altucci, L.; Amelio, I.; Andrews, D. W.; Aqeilan, R. I.; Arama, E.; Baehrecke, E. H.; Balachandran, S.; Bano, D.; Barlev, N. A.; Bartek, J.; Bazan, N. G.; Becker, C.; Bernassola, F.; Bertrand, M. J. M.; Bianchi, M. E.; Blagosklonny, M. V.; Blander, J. M.; Blandino, G.; Blomgren, K.; Borner, C.; Bortner, C. D.; Bove, P.; Boya, P.; Brenner, C.; Broz, P.; Brunner, T.; Damgaard, R. B.; Calin, G. A.; Campanella, M.; Candi, E.; Carbone, M.; Carmona-Gutierrez, D.; Cecconi, F.; Chan, F. K. -M.; Chen, G. -Q.; Chen, Q.; Chen, Y. H.; Cheng, E. H.; Chipuk, J. E.; Cidlowski, J. A.; Ciechanover, A.; Ciliberto, G.; Conrad, M.; Cubillos-Ruiz, J. R.; Czabotar, P. E.; D'Angiolella, V.; Daugaard, M.; Dawson, T. M.; Dawson, V. L.; De Maria, R.; De Strooper, B.; Debatin, K. -M.; Deberardinis, R. J.; Degterev, A.; Del Sal, G.; Deshmukh, M.; Di Virgilio, F.; Diederich, M.; Dixon, S. J.; Dynlacht, B. D.; El-Deiry, W. S.; Elrod, J. W.; Engeland, K.; Fimia, G. M.; Galassi, C.; Ganini, C.; Garcia-Saez, A. J.; Garg, A. D.; Garrido, C.; Gavathiotis, E.; Gerlic, M.; Ghosh, S.; Green, D. R.; Greene, L. A.; Gronemeyer, H.; Hacker, G.; Hajnoczky, G.; Hardwick, J. M.; Haupt, Y.; He, S.; Heery, D. M.; Hengartner, M. O.; Hetz, C.; Hildeman, D. A.; Ichijo, H.; Inoue, S.; Jaattela, M.; Janic, A.; Joseph, B.; Jost, P. J.; Kanneganti, T. -D.; Karin, M.; Kashkar, H.; Kaufmann, T.; Kelly, G. L.; Kepp, O.; Kimchi, A.; Kitsis, R. N.; Klionsky, D. J.; Kluck, R.; Krysko, D. V.; Kulms, D.; Kumar, S.; Lavandero, S.; Lavrik, I. N.; Lemasters, J. J.; Liccardi, G.; Linkermann, A.; Lipton, S. A.; Lockshin, R. A.; Lopez-Otin, C.; Luedde, T.; Macfarlane, M.; Madeo, F.; Malorni, W.; Manic, G.; Mantovani, R.; Marchi, S.; Marine, J. -C.; Martin, S. J.; Martinou, J. -C.; Mastroberardino, P. G.; Medema, J. P.; Mehlen, P.; Meier, P.; Melino, G.; Melino, S.; Miao, E. A.; Moll, U. M.; Munoz-Pinedo, C.; Murphy, D. J.; Niklison-Chirou, M. V.; Novelli, F.; Nunez, G.; Oberst, A.; Ofengeim, D.; Opferman, J. T.; Oren, M.; Pagano, M.; Panaretakis, T.; Pasparakis, M.; Penninger, J. M.; Pentimalli, F.; Pereira, D. M.; Pervaiz, S.; Peter, M. E.; Pinton, P.; Porta, G.; Prehn, J. H. M.; Puthalakath, H.; Rabinovich, G. A.; Rajalingam, K.; Ravichandran, K. S.; Rehm, M.; Ricci, J. -E.; Rizzuto, R.; Robinson, N.; Rodrigues, C. M. P.; Rotblat, B.; Rothlin, C. V.; Rubinsztein, D. C.; Rudel, T.; Rufini, A.; Ryan, K. M.; Sarosiek, K. A.; Sawa, A.; Sayan, E.; Schroder, K.; Scorrano, L.; Sesti, F.; Shao, F.; Shi, Y.; Sica, G. S.; Silke, J.; Simon, H. -U.; Sistigu, A.; Stephanou, A.; Stockwell, B. R.; Strapazzon, F.; Strasser, A.; Sun, L.; Sun, E.; Sun, Q.; Szabadkai, G.; Tait, S. W. G.; Tang, D.; Tavernarakis, N.; Troy, C. M.; Turk, B.; Urbano, N.; Vandenabeele, P.; Vanden Berghe, T.; Vander Heiden, M. G.; Vanderluit, J. L.; Verkhratsky, A.; Villunger, A.; von Karstedt, S.; Voss, A. K.; Vousden, K. H.; Vucic, D.; Vuri, D.; Wagner, E. F.; Walczak, H.; Wallach, D.; Wang, R.; Wang, Y.; Weber, A.; Wood, W.; Yamazaki, T.; Yang, H. -T.; Zakeri, Z.; Zawacka-Pankau, J. E.; Zhang, L.; Zhang, H.; Zhivotovsky, B.; Zhou, W.; Piacentini, M.; Kroemer, G.; Galluzzi, L.
Identification and functional validation of FDA-approved positive and negative modulators of the mitochondrial calcium uniporter
2021 De Mario, A.; Tosatto, A.; Hill, J. M.; Kriston-Vizi, J.; Ketteler, R.; Vecellio Reane, D.; Cortopassi, G.; Szabadkai, G.; Rizzuto, R.; Mammucari, C.
PICALM rescues glutamatergic neurotransmission, behavioural function and survival in a Drosophila model of Aβ42 toxicity
2020 Yu, Y.; Niccoli, T.; Ren, Z.; Woodling, N. S.; Aleyakpo, B.; Szabadkai, G.; Partridge, L.
Impaired cellular bioenergetics caused by GBA1 depletion sensitizes neurons to calcium overload
2020 Plotegher, N.; Perocheau, D.; Ferrazza, R.; Massaro, G.; Bhosale, G.; Zambon, F.; Rahim, A. A.; Guella, G.; Waddington, S. N.; Szabadkai, G.; Duchen, M. R.
Mitochondria form contact sites with the nucleus to couple prosurvival retrograde response
2020 Desai, R.; East, D. A.; Hardy, L.; Faccenda, D.; Rigon, M.; Crosby, J.; Alvarez, M. S.; Singh, A.; Mainenti, M.; Hussey, L. K.; Bentham, R.; Szabadkai, G.; Zappulli, V.; Dhoot, G. K.; Romano, L. E.; Xia, D.; Coppens, I.; Hamacher-Brady, A.; Paul Chapple, J.; Abeti, R.; Fleck, R. A.; Vizcay-Barrena, G.; Smith, K.; Campanella, M.
Macrophages induce malignant traits in mammary epithelium via IKK epsilon/TBK1 kinases and the serine biosynthesis pathway
2020 Wilcz-Villega, E; Carter, E; Ironside, A; Xu, Ry; Mataloni, I; Holdsworth, J; Jones, W; Bejar, Rm; Uhlik, L; Bentham, Rb; Godinho, Sa; Dalli, J; Grose, R; Szabadkai, G; Jones, L; Hodivala-Dilke, K; Bianchi, K
The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism
2020 Xu, R.; Jones, W.; Wilcz-Villega, E.; Costa, A. S. H.; Rajeeve, V.; Bentham, R. B.; Bryson, K.; Nagano, A.; Yaman, B.; Olendo Barasa, S.; Wang, Y.; Chelala, C.; Cutillas, P.; Szabadkai, G.; Frezza, C.; Bianchi, K.
Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway
2020 Wilcz-Villega, E.; Carter, E.; Ironside, A.; Xu, R.; Mataloni, I.; Holdsworth, J.; Jones, W.; Moreno Bejar, R.; Uhlik, L.; Bentham, R. B.; Godinho, S. A.; Dalli, J.; Grose, R.; Szabadkai, G.; Jones, L.; Hodivala-Dilke, K.; Bianchi, K.
Fantastic beasts and how to find them—Molecular identification of the mitochondrial ATP-sensitive potassium channel
2019 Davidson, S. M.; Szabadkai, G.; Duchen, M. R.
Determination of ATP, ADP, and AMP levels by reversed-phase high-performance liquid chromatography in cultured cells
2019 Menegollo, Michela; Tessari, Isabella; Bubacco, Luigi; Szabadkai, Gyorgy
Hyperpolarised 13C MRI: a new horizon for non-invasive diagnosis of aggressive breast cancer
2019 Abeyakoon, Oshaani; Latifoltojar, Arash; Gong, Fiona; Papoutsaki, Marianthi-Vasiliki; Chowdhury, Rafat; Glaser, Matthias; Jeraj, Hassan; Awais, Ramla; Holt, Christopher; Twyman, Frazer; Arstad, Erik; Gadian, David G; Atkinson, David; Comment, Arnaud; O'Callaghan, James; Smith, Lorna; Beeston, Teresita; Clemente, Joey; Patani, Neill; Stein, Rob; Yuneva, Mariia; Szabadkai, Gyorgy; Halligan, Steve; Punwani, Shonit
CHCHD4 regulates tumour proliferation and EMT-related phenotypes, through respiratory chain-mediated metabolism
2019 Thomas, Luke W; Esposito, Cinzia; Stephen, Jenna M; Costa, Ana S H; Frezza, Christian; Blacker, Thomas S; Szabadkai, Gyorgy; Ashcroft, Margaret
Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Adaptations and Targets in Cancer
2019 Avnet, S.; Baldini, N.; Brisson, L.; Pedersen, S. F.; Porporato, P. E.; Sonveaux, P.; Szabadkai, G.; Pastorekova, S.
Metabolic profiling of live cancer tissues using NAD(P)H fluorescence lifetime imaging
2019 Blacker, T. S.; Sewell, M. D. E.; Szabadkai, G.; Duchen, M. R.
MLH1 deficiency leads to deregulated mitochondrial metabolism
2019 Rashid, S.; Freitas, M. O.; Cucchi, D.; Bridge, G.; Yao, Z.; Gay, L.; Williams, M.; Wang, J.; Suraweera, N.; Silver, A.; Mcdonald, S. A. C.; Chelala, C.; Szabadkai, G.; Martin, S. A.
Biclustering analysis of co-regulation patterns in nuclear-encoded mitochondrial genes and metabolic pathways
2019 Bentham, R. B.; Bryson, K.; Szabadkai, G.
Mitochondrial Permeability Transition: A Molecular Lesion with Multiple Drug Targets
2019 Briston, T.; Selwood, D. L.; Szabadkai, G.; Duchen, M. R.
Targeting RORs nuclear receptors by novel synthetic steroidal inverse agonists for autoimmune disorders
2018 DAL PRA', Matteo; Carta, Davide; Szabadkai, Gyorgy; Suman, Matteo; Frión-Herrera, Yahima; Paccagnella, Nicola; Castellani, Giulia; De Martin, Sara; Ferlin, Maria Grazia
DJ-1 is a redox sensitive adapter protein for high molecular weight complexes involved in regulation of catecholamine homeostasis
2018 Piston, Dominik; Alvarez-Erviti, Lydia; Bansal, Vikas; Gargano, Daniela; Yao, Zhi; Szabadkai, Gyorgy; Odell, Mark; Puno, M Rhyan; Björkblom, Benny; Maple-Grødem, Jodi; Breuer, Peter; Kaut, Oliver; Larsen, Jan Petter; Bonn, Stefan; Møller, Simon Geir; Wüllner, Ullrich; Schapira, Anthony H V; Gegg, Matthew E
Inositol trisphosphate receptor-mediated Ca 2+ signalling stimulates mitochondrial function and gene expression in core myopathy patients
2018 Suman, Matteo; Sharpe, Jenny A.; Bentham, Robert B.; Kotiadis, Vassilios N.; Menegollo, Michela; Pignataro, Viviana; Molgó, Jordi; Muntoni, Francesco; Duchen, Michael R.; Pegoraro, Elena; Szabadkai, Gyorgy
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