Sfoglia per Autore
Improved efficacy of quizartinib in combination therapy with PI3K inhibition in primary FLT3-ITD AML cells
2023 Darici, Salihanur; Jørgensen, Heather G; Huang, Xu; Serafin, Valentina; Antolini, Ludovica; Barozzi, Patrizia; Luppi, Mario; Forghieri, Fabio; Marmiroli, Sandra; Zavatti, Manuela
Emerging Epigenetic and Posttranslational Mechanisms Controlling Resistance to Glucocorticoids in Acute Lymphoblastic Leukemia
2023 Borin, Cristina; Pieters, Tim; Serafin, Valentina; Ntziachristos, Panagiotis
CircFBXW7 in patients with T-cell ALL: depletion sustains MYC and NOTCH activation and leukemia cell viability
2023 Buratin, Alessia; Borin, Cristina; Tretti Parenzan, Caterina; Dal Molin, Anna; Orsi, Silvia; Binatti, Andrea; Simon, Katharina; Paganin, Maddalena; Serafin, Valentina; Gaffo, Enrico; Te Kronnie, Geertruij; Van Vlierberghe, Pieter; Bresolin, Silvia; Bortoluzzi, Stefania
Targeting NOTCH1 in combination with antimetabolite drugs prolongs life span in relapsed pediatric and adult T-acute lymphoblastic leukemia xenografts
2023 Minuzzo, Sonia; Agnusdei, Valentina; Pinazza, Marica; Amaro, Adriana A; Sacchetto, Valeria; Pfeffer, Ulrich; Bertorelle, Roberta; Spinelli, Orietta; Serafin, Valentina; Indraccolo, Stefano
A perfusion-based three-dimensional cell culture system to model alveolar rhabdomyosarcoma pathological features
2023 Saggioro, Mattia; D'Agostino, Stefania; Veltri, Giulia; Bacchiega, Maira; Tombolan, Lucia; Zanon, Carlo; Gamba, Piergiorgio; Serafin, Valentina; Muraro, Manuele Giuseppe; Martin, Ivan; Pozzobon, Michela
Functional relevance of circRNA aberrant expression in pediatric acute leukemia with KMT2A::AFF1 fusion
2023 Tretti Parenzan, Caterina; Dal Molin, Anna; Longo, Giorgia; Gaffo, Enrico; Buratin, Alessia; Cani, Alice; Boldrin, Elena; Serafin, Valentina; Guglielmelli, Paola; Vannucchi, Alessandro M; Cazzaniga, Giovanni; Biondi, Andrea; Locatelli, Franco; Meyer, Lueder Hinrich; Buldini, Barbara; Te Kronnie, Geertruij; Bresolin, Silvia; Bortoluzzi, Stefania
Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia
2022 Jin, Qi; Gutierrez Diaz, Blanca; Pieters, Tim; Zhou, Yalu; Narang, Sonali; Fijalkwoski, Igor; Borin, Cristina; Van Laere, Jolien; Payton, Monique; Cho, Byoung-Kyu; Han, Cuijuan; Sun, Limin; Serafin, Valentina; Yacu, George; Von Loocke, Wouter; Basso, Giuseppe; Veltri, Giulia; Dreveny, Ingrid; Ben-Sahra, Issam; Goo, Young Ah; Safgren, Stephanie L; Tsai, Yi-Chien; Bornhauser, Beat; Suraneni, Praveen Kumar; Gaspar-Maia, Alexandre; Kandela, Irawati; Van Vlierberghe, Pieter; Crispino, John D; Tsirigos, Aristotelis; Ntziachristos, Panagiotis
A rhabdomyosarcoma hydrogel model to unveil cell-extracellular matrix interactions
2022 Saggioro, Mattia; D'Agostino, Stefania; Gallo, Anna; Crotti, Sara; D'Aronco, Sara; Corallo, Diana; Veltri, Giulia; Martinez, Gabriele; Grigoletto, Antonella; Tolomeo, Anna Maria; Tafuro, Giovanni; Agostini, Marco; Aveic, Sanja; Serafin, Valentina; Semenzato, Alessandra; Pasut, Gianfranco; Pozzobon, Michela
Phosphoproteomic Analysis Reveals a Different Proteomic Profile in Pediatric Patients With T-Cell Lymphoblastic Lymphoma or T-Cell Acute Lymphoblastic Leukemia
2022 Veltri, Giulia; Lovisa, Federica; Cortese, Giuliana; Pillon, Marta; Carraro, Elisa; Cesaro, Simone; Provenzi, Massimo; Buffardi, Salvatore; Francescato, Samuela; Biffi, Alessandra; Buldini, Barbara; Conter, Valentino; Serafin, Valentina; Mussolin, Lara
SF3B1 homeostasis is critical for survival and therapeutic response in T cell leukemia
2022 Han, Cuijuan; Khodadadi-Jamayran, Alireza; Lorch, Adam H.; Jin, Qi; Serafin, Valentina; Zhu, Ping; Politanska, Yuliya; Sun, Limin; Gutierrez-Diaz, Blanca T.; Pryzhkova, Marina V.; Abdala-Valencia, Hiam; Bartom, Elizabeth Thomas; Buldini, Barbara; Basso, Giuseppe; Velu, Sadanandan E.; Sarma, Kavitha; Mattamana, Basil B.; Cho, Byoung-Kyu; Obeng, Rebecca C.; Goo, Young Ah; Jordan, Philip W.; Tsirigos, Aristotelis; Zhou, Yalu; Ntziachristos, Panagiotis
NUP214-ABL1 fusion in childhood T-ALL
2022 Veltri, Giulia; Sandei, Max; Silvestri, Daniela; Bresolin, Silvia; Pession, Andrea; Santoro, Nicola; Ziino, Ottavio; Veltroni, Marinella; Rizzari, Carmelo; Biffi, Alessandra; Valsecchi, Maria Grazia; Conter, Valentino; Buldini, Barbara; Accordi, Benedetta; Serafin, Valentina
Ruxolitinib as a novel therapeutic option for poor prognosis t-lbl pediatric patients
2021 Veltri, G.; Silvestri, C.; Gallingani, I.; Sandei, M.; Vencato, S.; Lovisa, F.; Cortese, G.; Pillon, M.; Carraro, E.; Bresolin, S.; Biffi, A.; Basso, G.; Accordi, B.; Mussolin, L.; Serafin, V.
Editorial: Special Issue on Innovative Multi-Disciplinary Approaches for Precision Studies in Leukemia
2021 Marmiroli, S.; Huang, X.; Serafin, V.; Michie, A. M.
Synergistic cytotoxicity of dual PI3K/mTOR and FLT3 inhibition in FLT3-ITD AML cells
2021 Darici, S.; Zavatti, M.; Braglia, L.; Accordi, B.; Serafin, V.; Horne, G. A.; Manzoli, L.; Palumbo, C.; Huang, X.; Jorgensen, H. G.; Marmiroli, S.
Large-scale circular RNA deregulation in T-ALL: Unlocking unique ectopic expression of molecular subtypes
2020 Buratin, A.; Paganin, M.; Gaffo, E.; Dal Molin, A.; Roels, J.; Germano, G.; Siddi, M. T.; Serafin, V.; de Decker, M.; Gachet, S.; Durinck, K.; Speleman, F.; Taghon, T.; te Kronnie, G.; van Vlierberghe, P.; Bortoluzzi, S.
Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia
2020 Zhou, Yalu; Han, Cuijuan; Wang, Eric; Lorch, Adam H; Serafin, Valentina; Cho, Byoung-Kyu; Gutierrez Diaz, Blanca T; Calvo, Julien; Fang, Celestia; Khodadadi-Jamayran, Alireza; Tabaglio, Tommaso; Marier, Christian; Kuchmiy, Anna; Sun, Limin; Yacu, George; Filip, Szymon K; Jin, Qi; Takahashi, Yoh-Hei; Amici, David R; Rendleman, Emily J; Rawat, Radhika; Bresolin, Silvia; Paganin, Maddalena; Zhang, Cheng; Li, Hu; Kandela, Irawati; Politanska, Yuliya; Abdala-Valencia, Hiam; Mendillo, Marc L; Zhu, Ping; Palhais, Bruno; Van Vlierberghe, Pieter; Taghon, Tom; Aifantis, Iannis; Goo, Young Ah; Guccione, Ernesto; Heguy, Adriana; Tsirigos, Aristotelis; Wee, Keng Boon; Mishra, Rama K; Pflumio, Francoise; Accordi, Benedetta; Basso, Giuseppe; Ntziachristos, Panagiotis
RSK inhibitor BI-D1870 inhibits acute myeloid leukemia cell proliferation by targeting mitotic exit
2020 Chae, H. -D.; Dutta, R.; Tiu, B.; Hoff, F. W.; Accordi, B.; Serafin, V.; Youn, M.; Huang, M.; Sumarsono, N.; Davis, K. L.; Lacayo, N. J.; Pigazzi, M.; Horton, T. M.; Kornblau, S. M.; Sakamoto, K. M.
Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation
2020 Fang, C.; Wang, Z.; Han, C.; Safgren, S. L.; Helmin, K. A.; Adelman, E. R.; Serafin, V.; Basso, G.; Eagen, K. P.; Gaspar-Maia, A.; Figueroa, M. E.; Singer, B. D.; Ratan, A.; Ntziachristos, P.; Zang, C.
Pre-clinical evaluation of second generation pim inhibitors for the treatment of t-cell acute lymphoblastic leukemia and lymphoma
2019 De Smedt, Renate; Peirs, Sofie; Morscio, Julie; Matthijssens, Filip; Roels, Juliette; Reunes, Lindy; Lintermans, Beatrice; Goossens, Steven; Lammens, Tim; Van Roy, Nadine; Touzart, Aurore; Jenni, Silvia; Tsai, Yi-Chien; Lovisa, Federica; Mussolin, Lara; Serafin, Valentina; Van Nieuwerburgh, Filip; Deforce, Dieter; Uyttebroeck, Anne; Tousseyn, Thomas; Burkhardt, Birgit; Klapper, Wolfram; De Moerloose, Barbara; Benoit, Yves; Macintyre, Elizabeth; Bourquin, Jean-Pierre; Basso, Giuseppe; Accordi, Benedetta; Bornhauser, Beat; Meijerink, JULES PETER PAUL; Vandenberghe, Peter; Van Vlierberghe, Pieter
USP7 cooperates with NOTch1 to drive the oncogenic transcriptional program in T-cell leukemia
2019 Jin, Q.; ECHEVERRIA MARTINEZ, CARLOS ANTONIO; Arcipowski, K. M.; Zhu, Y.; Gutierrez-Diaz, B. T.; Wang, K. K.; Johnson, M. R.; Volk, A. G.; Wang, F.; Wu, J.; Grove, C.; Wang, H.; Sokirniy, I.; Thomas, P. M.; Goo, Y. A.; Abshiru, N. A.; Hijiya, N.; Peirs, S.; Vandamme, N.; Berx, G.; Goosens, S.; Marshall, S. A.; Rendleman, E. J.; Takahashi, Y. -H.; Wang, L.; Rawat, R.; Bartom, E. T.; Collings, C. K.; Van Vlierberghe, P.; Strikoudis, A.; Kelly, S.; Ueberheide, B.; Mantis, C.; Kandela, I.; Bourquin, J. -P.; Bornhauser, B.; Serafin, V.; Bresolin, S.; Paganin, M.; Accordi, B.; Basso, G.; Kelleher, N. L.; Weinstock, J.; Kumar, S.; Crispino, J. D.; Shilatifard, A.; Ntziachristos, P.
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