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Titolo Data di pubblicazione Autori Rivista Serie Titolo libro
Human neural progenitor cell models to study the antiviral effects and neuroprotective potential of approved and investigational human cytomegalovirus inhibitors 2024 Trevisan M.Apolloni L.Mercorelli B.Loregian A. + ANTIVIRAL RESEARCH - -
Design, Synthesis, and Biological Evaluation of Trisubstituted Piperazine Derivatives as Noncovalent Severe Acute Respiratory Syndrome Coronavirus 2 Main Protease Inhibitors with Improved Antiviral Activity and Favorable Druggability 2023 Mercorelli B.Loregian A. + JOURNAL OF MEDICINAL CHEMISTRY - -
A small molecule targeting the interaction between human papillomavirus E7 oncoprotein and cellular phosphatase PTPN14 exerts antitumoral activity in cervical cancer cells 2023 Bertagnin C.Celegato M.Sturlese M.Mercorelli B.Moro S.Loregian A. + CANCER LETTERS - -
Small-Molecule Inhibitor of Flaviviral NS3-NS5 Interaction with Broad-Spectrum Activity and Efficacy In Vivo 2023 Celegato M.Sturlese M.Trevisan M.Favaro A.Moro S.Loregian A.Mercorelli B. + MBIO - -
Discovery of novel SARS-CoV-2 inhibitors targeting the main protease Mpro by virtual screenings and hit optimization 2022 Mercorelli, BeatriceDesantis, JennyCelegato, MartaBazzacco, AlessandroLoregian, Arianna + ANTIVIRAL RESEARCH - -
Targeted disruption of e6/p53 binding exerts broad activity and synergism with paclitaxel and topotecan against hpv-transformed cancer cells 2022 Celegato M.Messa L.Bertagnin C.Mercorelli B.Loregian A. CANCERS - -
The antifungal drug isavuconazole inhibits the replication of human cytomegalovirus (HCMV) and acts synergistically with anti-HCMV drugs 2021 Mercorelli B.Celegato M.Gribaudo G.Loregian A. + ANTIVIRAL RESEARCH - -
Divide et impera: An In Silico Screening Targeting HCMV ppUL44 Processivity Factor Homodimerization Identifies Small Molecules Inhibiting Viral Replication 2021 Ghassabian, HaniehTimmoneri, MMercorelli, BLoregian, APalu, GAlvisi, G + VIRUSES - -
Indomethacin-based PROTACs as pan-coronavirus antiviral agents 2021 Desantis J.Mercorelli B.Celegato M.Bazzacco A.Loregian A. + EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY - -
The dimeric form of hpv16 e6 is crucial to drive yap/taz upregulation through the targeting of hscrib 2021 Messa L.Celegato M.Bertagnin C.Mercorelli B.Alvisi G.Palu G.Loregian A. + CANCERS - -
A novel small-molecule inhibitor of the human papillomavirus E6-p53 interaction that reactivates p53 function and blocks cancer cells growth 2020 Celegato M.Messa L.Mercorelli B.Bertagnin C.Palu G.Loregian A. + CANCER LETTERS - -
The Clinically Approved Antifungal Drug Posaconazole Inhibits Human Cytomegalovirus Replication 2020 Beatrice MercorelliMarta CelegatoGiorgio PalùGiorgio GribaudoArianna Loregian + ANTIMICROBIAL AGENTS AND CHEMOTHERAPY - -
The isoquinoline alkaloid berberine inhibits human cytomegalovirus replication by interfering with the viral Immediate Early-2 (IE2) protein transactivating activity 2019 Mercorelli, BeatriceMessa, LorenzoPalù, GiorgioGribaudo, GiorgioLoregian, Arianna + ANTIVIRAL RESEARCH - -
Potent and broad-spectrum cycloheptathiophene-3-carboxamide compounds that target the PA-PB1 interaction of influenza virus RNA polymerase and possess a high barrier to drug resistance 2019 Nannetti, GiulioMercorelli, BeatriceBertagnin, ChiaraPalù, GiorgioLoregian, Arianna + ANTIVIRAL RESEARCH - -
Drug Repurposing Campaigns for Human Cytomegalovirus Identify a Natural Compound Targeting the Immediate-Early 2 (IE2) Protein: A Comment on "The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication within Fibroblasts" 2019 Mercorelli, BeatricePalù, GiorgioGribaudo, GiorgioLoregian, Arianna + VIRUSES - -
Drug Repurposing for Viral Infectious Diseases: How Far Are We? 2018 Mercorelli, BeatricePalù, GiorgioLoregian, Arianna TRENDS IN MICROBIOLOGY - -
Repurposing the clinically approved calcium antagonist manidipine dihydrochloride as a new early inhibitor of human cytomegalovirus targeting the Immediate-Early 2 (IE2) protein 2018 Mercorelli, BeatriceCelegato, MartaPalù, GiorgioGribaudo, GiorgioLoregian, Arianna + ANTIVIRAL RESEARCH - -
A quantitative LumiFluo assay to test inhibitory compounds blocking p53 degradation induced by human papillomavirus oncoprotein E6 in living cells 2018 Messa, LorenzoCelegato, MartaBertagnin, ChiaraMercorelli, BeatriceNannetti, GiulioPalù, GiorgioLoregian, Arianna SCIENTIFIC REPORTS - -
Drug Repurposing Approach Identifies Inhibitors of the Prototypic Viral Transcription Factor IE2 that Block Human Cytomegalovirus Replication 2016 MERCORELLI, BEATRICENANNETTI, GIULIOPALU', GIORGIOLOREGIAN, ARIANNA + CELL CHEMICAL BIOLOGY - -
4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling 2016 NANNETTI, GIULIOMERCORELLI, BEATRICEPALU', GIORGIOLOREGIAN, ARIANNA + JOURNAL OF MEDICINAL CHEMISTRY - -
Mostrati risultati da 1 a 20 di 40
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