Sfoglia per Autore
Identification of novel therapeutic approaches to selectively target senescent cells in prostate cancer
In corso di stampa Bressan, Silvia; Brina, Daniela; Zumerle, Sara; Montopoli, Monica; Alimonti, Andrea
Retinoic acid receptor activation reprograms senescence response and enhances anti-tumor activity of natural killer cells
2024 Colucci, Manuel; Zumerle, Sara; Bressan, Silvia; Gianfanti, Federico; Troiani, Martina; Valdata, Aurora; D’Ambrosio, Mariantonietta; Pasquini, Emiliano; Varesi, Angelica; Cogo, Francesca; Mosole, Simone; Dongilli, Cristina; Desbats, Maria Andrea; Contu, Liliana; Revankdar, Ajinkya; Chen, Jingjing; Kalathur, Madhuri; Perciato, Maria Luna; Basilotta, Rossella; Endre, Laczko; Schauer, Stefan; Othman, Alaa; Guccini, Ilaria; Saponaro, Miriam; Maraccani, Luisa; Bancaro, Nicolò; Lai, Ping; Liu, Lei; Pernigoni, Nicolò; Mele, Federico; Merler, Sara; Trotman, Lloyd C.; Guarda, Greta; Calì, Bianca; Montopoli, Monica; Alimonti, Andrea
The potential role of the microbiota in prostate cancer pathogenesis and treatment
2023 Pernigoni, N; Guo, Csa; Gallagher, L; Yuan, W; Colucci, M; Troiani, M; Liu, L; Maraccani, L; Guccini, I; Migliorini, D; de Bono, J; Alimonti, A
VSSP-activated macrophages mediate senescence and tumor inhibition in a preclinical model of advanced prostate cancer
2023 Alvarez-Arzola, Rydell; Bancaro, Nicoló; Lai, Ping; Attanasio, Giuseppe; Pellegrini, Laura; Troiani, Martina; Colucci, Manuel; Mosole, Simone; Pasquini, Emiliano; Alimonti, Andrea; Mesa, Circe
Esmethadone-HCl (REL-1017): a promising rapid antidepressant
2023 Fava, Maurizio; Stahl, Stephen M; De Martin, Sara; Mattarei, Andrea; Bettini, Ezio; Comai, Stefano; Alimonti, Andrea; Bifari, Francesco; Pani, Luca; Folli, Franco; Guidetti, Clotilde; Furlan, Alberto; Sgrignani, Jacopo; Locatelli, Patrizia; Cavalli, Andrea; O'Gorman, Cedric; Traversa, Sergio; Inturrisi, Charles E; Pappagallo, Marco; Manfredi, Paolo L
Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer
2023 Bancaro, Nicolò; Calì, Bianca; Troiani, Martina; Elia, Angela Rita; Arzola, Rydell Alvarez; Attanasio, Giuseppe; Lai, Ping; Crespo, Mateus; Gurel, Bora; Pereira, Rita; Guo, Christina; Mosole, Simone; Brina, Daniela; D'Ambrosio, Mariantonietta; Pasquini, Emiliano; Spataro, Clarissa; Zagato, Elena; Rinaldi, Andrea; Pedotti, Mattia; Di Lascio, Simona; Meani, Francesco; Montopoli, Monica; Ferrari, Matteo; Gallina, Andrea; Varani, Luca; Pereira Mestre, Ricardo; Bolis, Marco; Gillessen Sommer, Silke; de Bono, Johann; Calcinotto, Arianna; Alimonti, Andrea
Genetic ablation of ketohexokinase C isoform impairs pancreatic cancer development
2023 Guccini, Ilaria; Tang, Guanghui; To, Trang Thuy; Di Rito, Laura; Le Blanc, Solange; Strobel, Oliver; D'Ambrosio, Mariantonietta; Pasquini, Emiliano; Bolis, Marco; Silva, Pamuditha; Kabakci, Hasan Ali; Godbersen, Svenja; Alimonti, Andrea; Schwank, Gerald; Stoffel, Markus
CDCP1 expression is frequently increased in aggressive urothelial carcinoma and promotes urothelial tumor progression
2023 Saponaro, Miriam; Flottmann, Sina; Eckstein, Markus; Hommerding, Oliver; Klümper, Niklas; Corvino, Dillon; Hosni, Sana; Schmidt, Anja; Mönig, Nicolas; Schmidt, Doris; Ellinger, Jörg; Toma, Marieta; Kristiansen, Glen; Bald, Tobias; Alimonti, Andrea; Ritter, Manuel; Hölzel, Michael; Alajati, Abdullah
The Akt/mTOR and MNK/eIF4E pathways rewire the prostate cancer translatome to secrete HGF, SPP1 and BGN and recruit suppressive myeloid cells
2023 Brina, Daniela; Ponzoni, Adele; Troiani, Martina; Calì, Bianca; Pasquini, Emiliano; Attanasio, Giuseppe; Mosole, Simone; Mirenda, Michela; D'Ambrosio, Mariantonietta; Colucci, Manuel; Guccini, Ilaria; Revandkar, Ajinkya; Alajati, Abdullah; Tebaldi, Toma; Donzel, Deborah; Lauria, Fabio; Parhizgari, Nahjme; Valdata, Aurora; Maddalena, Martino; Calcinotto, Arianna; Bolis, Marco; Rinaldi, Andrea; Barry, Simon; Rüschoff, Jan Hendrik; Sabbadin, Marianna; Sumanasuriya, Semini; Crespo, Mateus; Sharp, Adam; Yuan, Wei; Grinu, Mathew; Boyle, Alexandra; Miller, Cynthia; Trotman, Lloyd; Delaleu, Nicolas; Fassan, Matteo; Moch, Holger; Viero, Gabriella; de Bono, Johann; Alimonti, Andrea
Single-cell transcriptomics identifies Mcl-1 as a target for senolytic therapy in cancer
2022 Troiani, M.; Colucci, M.; D'Ambrosio, M.; Guccini, I.; Pasquini, E.; Varesi, A.; Valdata, A.; Mosole, S.; Revandkar, A.; Attanasio, G.; Rinaldi, A.; Rinaldi, A.; Bolis, M.; Cippa, P.; Alimonti, A.
B7-H3 as a Therapeutic Target in Advanced Prostate Cancer
2022 Guo, Christina; Figueiredo, Ines; Gurel, Bora; Neeb, Antje; Seed, George; Crespo, Mateus; Carreira, Suzanne; Rekowski, Jan; Buroni, Lorenzo; Welti, Jon; Bogdan, Denisa; Gallagher, Lewis; Sharp, Adam; Fenor de la Maza, Maria D.; Rescigno, Pasquale; Westaby, Daniel; Chandran, Khobe; Riisnaes, Ruth; Ferreira, Ana; Miranda, Susana; Cali', Bianca; Alimonti, Andrea; Bressan, Silvia; Nguyen, Alana H. T.; Shen, Michael M.; Hawley, Jessica E.; Obradovic, Aleksandar; Drake, Charles G.; Bertan, Claudia; Baker, Chloe; Tunariu, Nina; Yuan, Wei; de Bono, Johann S.
Pharmacological Comparative Characterization of REL-1017 (Esmethadone-HCl) and Other NMDAR Channel Blockers in Human Heterodimeric N-Methyl-D-Aspartate Receptors
2022 Bettini, Ezio; Stahl, Stephen M; De Martin, Sara; Mattarei, Andrea; Sgrignani, Jacopo; Carignani, Corrado; Nola, Selena; Locatelli, Patrizia; Pappagallo, Marco; Inturrisi, Charles E; Bifari, Francesco; Cavalli, Andrea; Alimonti, Andrea; Pani, Luca; Fava, Maurizio; Traversa, Sergio; Folli, Franco; Manfredi, Paolo L
Esmethadone (REL-1017) and Other Uncompetitive NMDAR Channel Blockers May Improve Mood Disorders via Modulation of Synaptic Kinase-Mediated Signaling
2022 Stahl, Stephen M; De Martin, Sara; Mattarei, Andrea; Bettini, Ezio; Pani, Luca; Guidetti, Clotilde; Folli, Franco; de Somer, Marc; Traversa, Sergio; Inturrisi, Charles E; Pappagallo, Marco; Gentilucci, Marco; Alimonti, Andrea; Fava, Maurizio; Manfredi, Paolo L
REL-1017 (Esmethadone) as Adjunctive Treatment in Patients With Major Depressive Disorder: A Phase 2a Randomized Double-Blind Trial
2022 Fava, M.; Stahl, S.; Pani, L.; De Martin, S.; Pappagallo, M.; Guidetti, C.; Alimonti, A.; Bettini, E.; Mangano, R. M.; Wessel, T.; de Somer, M.; Caron, J.; Vitolo, O. V.; Diguglielmo, G. R.; Gilbert, A.; Mehta, H.; Kearney, M.; Mattarei, A.; Gentilucci, M.; Folli, F.; Traversa, S.; Inturrisi, C. E.; Manfredi, P. L.
Commensal bacteria promote endocrine resistance in prostate cancer through androgen biosynthesis
2021 Pernigoni, Nicolò; Zagato, Elena; Calcinotto, Arianna; Troiani, Martina; Mestre, Ricardo Pereira; Calì, Bianca; Attanasio, Giuseppe; Troisi, Jacopo; Minini, Mirko; Mosole, Simone; Revandkar, Ajinkya; Pasquini, Emiliano; Elia, Angela Rita; Bossi, Daniela; Rinaldi, Andrea; Rescigno, Pasquale; Flohr, Penny; Hunt, Joanne; Neeb, Antje; Buroni, Lorenzo; Guo, Christina; Welti, Jonathan; Ferrari, Matteo; Grioni, Matteo; Gauthier, Josée; Gharaibeh, Raad Z; Palmisano, Anna; Lucchini, Gladys Martinetti; D'Antonio, Eugenia; Merler, Sara; Bolis, Marco; Grassi, Fabio; Esposito, Antonio; Bellone, Matteo; Briganti, Alberto; Rescigno, Maria; Theurillat, Jean-Philippe; Jobin, Christian; Gillessen, Silke; de Bono, Johann; Alimonti, Andrea
Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis
2021 Guccini, I.; Revandkar, A.; D'Ambrosio, M.; Colucci, M.; Pasquini, E.; Mosole, S.; Troiani, M.; Brina, D.; Sheibani-Tezerji, R.; Elia, A. R.; Rinaldi, A.; Pernigoni, N.; Ruschoff, J. H.; Dettwiler, S.; De Marzo, A. M.; Antonarakis, E. S.; Borrelli, C.; Moor, A. E.; Garcia-Escudero, R.; Alajati, A.; Attanasio, G.; Losa, M.; Moch, H.; Wild, P.; Egger, G.; Alimonti, A.
CD38 in Advanced Prostate Cancers
2021 Guo, Christina; Crespo, Mateus; Gurel, Bora; Dolling, David; Rekowski, Jan; Sharp, Adam; Petremolo, Antonella; Sumanasuriya, Semini; Rodrigues, Daniel N; Ferreira, Ana; Pereira, Rita; Figueiredo, Ines; Mehra, Niven; Lambros, Maryou B K; Neeb, Antje; Gil, Veronica; Seed, George; Terstappen, Leon; Alimonti, Andrea; Drake, Charles G; Yuan, Wei; de Bono, Johann S
Identification of novel therapeutic approaches to selectively target senescent cells in prostate cancer
2021 Bressan, Silvia; Brina, Daniela; Zumerle, Sara; Montopoli, Monica; Alimonti, Andrea
A multidisciplinary approach for the identification and validation of novel prostate cancer targets - ABSTRACTS OF THE 40TH CONGRESS OF THE ITALIAN PHARMACOLOGICAL SOCIETY (SIF)
2021 Gianfanti, Federico; Andrea Desbats, Maria; Nicolò Fanelli, Giuseppe; Alimonti, Andrea; Montopoli, Monica
JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer
2021 Paschalis, Alec; Welti, Jonathan; Neeb, Antje J.; Yuan, Wei; Figueiredo, Ines; Pereira, Rita; Ferreira, Ana; Riisnaes, Ruth; Rodrigues, Daniel Nava; Jiménez-Vacas, Juan M.; Kim, Soojin; Uo, Takuma; Micco, Patrizio Di; Tumber, Anthony; Islam, Md. Saiful; Moesser, Marc A.; Abboud, Martine; Kawamura, Akane; Gurel, Bora; Christova, Rossitza; Gil, Veronica S.; Buroni, Lorenzo; Crespo, Mateus; Miranda, Susana; Lambros, Maryou B.; Carreira, Suzanne; Tunariu, Nina; Alimonti, Andrea; Al-Lazikani, Bissan; Schofield, Christopher J.; Plymate, Stephen R.; Sharp, Adam; de Bono, Johann S.
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