Sfoglia per Autore
Generation of human induced pluripotent stem cell line EURACi006-A and its isogenic gene-corrected line EURACi006-A-1 from an arrhythmogenic cardiomyopathy patient carrying the c.1643delG PKP2 mutation
2021 Meraviglia, V.; Ganesh, S.; Arendzen, C. H.; Freund, C.; Sommariva, E.; Rossini, A.; Bellin, M.
Uncoupling DNA damage from chromatin damage to detoxify doxorubicin
2020 Qiao, X.; Van Der Zanden, S. Y.; Wander, D. P. A.; Borras, D. M.; Song, J. -Y.; Li, X.; Duikeren, S. V.; Gils, N. V.; Rutten, A.; Herwaarden, T. V.; Tellingen, O. V.; Giacomelli, E.; Bellin, M.; Orlova, V.; Tertoolen, L. G. J.; Gerhardt, S.; Akkermans, J. J.; Bakker, J. M.; Zuur, C. L.; Pang, B.; Smits, A. M.; Mummery, C. L.; Smit, L.; Arens, R.; Li, J.; Overkleeft, H. S.; Neefj, J.
Expanding the editable genome and CRISPR-Cas9 versatility using DNA cutting-free gene targeting based on in trans paired nicking
2020 Chen, X.; Tasca, F.; Wang, Q.; Liu, J.; Janssen, J. M.; Brescia, M. D.; Bellin, M.; Szuhai, K.; Kenrick, J.; Frock, R. L.; Goncalves, M. A. F. V.
Engineered models of the human heart: directions and challenges
2020 Stein, J. M.; Mummery, C. L.; Bellin, M.
Mechanotransduction and adrenergic stimulation in Arrhythmogenic Cardiomyopathy: an overview of in vitro and in vivo models.
2020 Beffagna, Giorgia; Sommariva, Elena; Bellin, Milena
Generation of human induced pluripotent stem cell line LUMCi027-A and its isogenic gene-corrected line from a patient affected by arrhythmogenic cardiomyopathy and carrying the c.2013delC PKP2 mutation
2020 Meraviglia, Viviana; Arendzen, Christiaan H.; Tokb, Merve; Freund, Christian; Serena Maione, Angela; Sommariva, Elena; Bellin, Milena
Human-iPSC-Derived Cardiac Stromal Cells Enhance Maturation in 3D Cardiac Microtissues and Reveal Non-cardiomyocyte Contributions to Heart Disease
2020 Giacomelli, Elisa; Meraviglia, Viviana; Campostrini, Giulia; Cochrane, Amy; Cao, Xu; van Helden, Ruben W. J.; Krotenberg Garcia, Ana; Mircea, Maria; Kostidis, Sarantos; Davis, Richard P.; van Meer, Berend J.; Jost, Carolina R.; Koster, Abraham J.; Mei, Hailiang; Míguez, David G.; Mulder, Aat A.; Ledesma-Terrón, Mario; Pompilio, Giulio; Sala, Luca; Salvatori, Daniela C. F.; Slieker, Roderick C.; Sommariva, Elena; de Vries, Antoine A. F.; Giera, Martin; Semrau, Stefan; Tertoolen, Leon G. J.; Orlova, Valeria V.; Bellin, Milena; Mummery, Christine L.
A Miniaturized EHT Platform for Accurate Measurements of Tissue Contractile Properties
2020 Dostanić, M.; Windt, L. M.; Stein, J. M.; Van Meer, B. J.; Bellin, M.; Orlova, V.; Mastrangeli, M.; Mummery, C. L.; Sarro, P. M.
Generation of two human induced pluripotent stem cell lines, LUMCi020-A and LUMCi021-A, from two patients with Catecholaminergic Polymorphic Ventricular Tachycardia carrying heterozygous mutations in the RYR2 gene
2020 Meraviglia, V; Arendzen, Ch; Freund, C; Atsma, De; Mummery, Cl; Bellin, M
Calcium as a key player in arrhythmogenic cardiomyopathy: Adhesion disorder or intracellular alteration?
2019 Moccia, F.; Lodola, F.; Stadiotti, I.; Pilato, C. A.; Bellin, M.; Carugo, S.; Pompilio, G.; Sommariva, E.; Maione, A. S.
Crispr/Cas9 homologous recombination (HR)
2018 Bellin, M.
Large-Scale Simulation of the Phenotypical Variability Induced by Loss-of-Function Long QT Mutations in Human Induced Pluripotent Stem Cell Cardiomyocytes
2018 Paci, M.; Casini, S.; Bellin, M.; Hyttinen, J.; Severi, S.
Musclemotion: A versatile open software tool to quantify cardiomyocyte and cardiac muscle contraction in vitro and in vivo
2018 Sala, L.; Van Meer, B. J.; Tertoolen, L. G. J.; Bakkers, J.; Bellin, M.; Davis, R. P.; Denning, C.; Dieben, M. A. E.; Eschenhagen, T.; Giacomelli, E.; Grandela, C.; Hansen, A.; Holman, E. R.; Jongbloed, M. R. M.; Kamel, S. M.; Koopman, C. D.; Lachaud, Q.; Mannhardt, I.; Mol, M. P. H.; Mosqueira, D.; Orlova, V. V.; Passier, R.; Ribeiro, M. C.; Saleem, U.; Smith, G. L.; Burton, F. L.; Mummery, C. L.
Human heart disease: lessons from human pluripotent stem cell-derived cardiomyocytes
2017 Giacomelli, E.; Mummery, C. L.; Bellin, M.
Human Pluripotent Stem Cell Differentiation into Functional Epicardial Progenitor Cells
2017 Guadix, J. A.; Orlova, V. V.; Giacomelli, E.; Bellin, M.; Ribeiro, M. C.; Mummery, C. L.; Perez-Pomares, J. M.; Passier, R.
Subtype-specific promoter-driven action potential imaging for precise disease modelling and drug testing in hiPSC-derived cardiomyocytes
2017 Chen, Z.; Xian, W.; Bellin, M.; Dorn, T.; Tian, Q.; Goedel, A.; Dreizehnter, L.; Schneider, C. M.; Ward-Van Oostwaard, D.; Ng, J. K. M.; Hinkel, R.; Pane, L. S.; Mummery, C. L.; Lipp, P.; Moretti, A.; Laugwitz, K. -L.; Sinnecker, D.
Co-Differentiation of Human Pluripotent Stem Cells-Derived Cardiomyocytes and Endothelial Cells from Cardiac Mesoderm Provides a Three-Dimensional Model of Cardiac Microtissue
2017 Giacomelli, E.; Bellin, M.; Orlova, V. V.; Mummery, C. L.
Three-dimensional cardiac microtissues composed of cardiomyocytes and endothelial cells co-differentiated from human pluripotent stem cells
2017 Giacomelli, E.; Bellin, M.; Sala, L.; van Meer, B. J.; Tertoolen, L. G. J.; Orlova, V. V.; Mummery, C. L.
Integrating cardiomyocytes from human pluripotent stem cells in safety pharmacology: has the time come?
2017 Sala, L.; Bellin, M.; Mummery, C. L.
Switch from fetal to adult SCN5A isoform in human induced pluripotent stem cell-derived cardiomyocytes unmasks the cellular phenotype of a conduction disease-causing mutation
2017 Veerman, C. C.; Mengarelli, I.; Lodder, E. M.; Kosmidis, G.; Bellin, M.; Zhang, M.; Dittmann, S.; Guan, K.; Wilde, A. A. M.; Schulze-Bahr, E.; Greber, B.; Bezzina, C. R.; Verkerk, A. O.
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