LOREGIAN, ARIANNA
 Distribuzione geografica
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Continente #
NA - Nord America 8.054
EU - Europa 878
AS - Asia 544
SA - Sud America 13
AF - Africa 5
OC - Oceania 5
Totale 9.499
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Nazione #
US - Stati Uniti d'America 8.046
CN - Cina 480
IT - Italia 241
FI - Finlandia 173
DE - Germania 106
SE - Svezia 96
UA - Ucraina 82
GB - Regno Unito 62
FR - Francia 50
IE - Irlanda 41
IN - India 32
VN - Vietnam 20
BR - Brasile 7
CA - Canada 5
LU - Lussemburgo 5
SI - Slovenia 5
AU - Australia 4
CL - Cile 3
GH - Ghana 3
JP - Giappone 3
KR - Corea 3
MX - Messico 3
RO - Romania 3
DK - Danimarca 2
ES - Italia 2
PT - Portogallo 2
RU - Federazione Russa 2
UY - Uruguay 2
AT - Austria 1
BO - Bolivia 1
GR - Grecia 1
IL - Israele 1
LA - Repubblica Popolare Democratica del Laos 1
LI - Liechtenstein 1
LV - Lettonia 1
MA - Marocco 1
MO - Macao, regione amministrativa speciale della Cina 1
MY - Malesia 1
NL - Olanda 1
NZ - Nuova Zelanda 1
PL - Polonia 1
TH - Thailandia 1
TW - Taiwan 1
ZA - Sudafrica 1
Totale 9.499
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Città #
Fairfield 1.341
Woodbridge 863
Houston 736
Ashburn 648
Chandler 627
Ann Arbor 571
Seattle 511
Cambridge 492
Wilmington 463
Jacksonville 308
Princeton 175
San Diego 139
Beijing 112
Helsinki 95
Roxbury 87
Guangzhou 78
Des Moines 75
Padova 71
Boardman 66
Medford 60
Nanjing 59
Columbus 54
Dublin 41
Shanghai 36
Dearborn 31
Shenyang 24
Falls Church 22
London 20
Nanchang 20
Dong Ket 19
Norwalk 17
Pune 17
Hebei 16
Milan 16
Redwood City 16
New York 14
Kharkiv 13
Washington 12
Changsha 11
Jiaxing 10
Hefei 9
Kunming 8
Tappahannock 8
Ogden 7
Vicenza 7
Camponogara 6
Chicago 6
Aprilia 5
Borås 5
Crotone 5
Hanover 5
Jinan 5
Luxembourg 5
Bengaluru 4
Bergamo 4
Buffalo 4
Nürnberg 4
Paris 4
Tianjin 4
Abano Terme 3
Accra 3
Berlin 3
Chiswick 3
Florence 3
Fuzhou 3
Kilburn 3
Palermo 3
Pietro 3
Rome 3
San Francisco 3
Sydney 3
Taiyuan 3
Verona 3
Wuhan 3
Zhengzhou 3
Americana 2
Aversa 2
Belo Horizonte 2
Botucatu 2
Brasov 2
Chengdu 2
Copenhagen 2
Edinburgh 2
Falkenstein 2
Frankfurt am Main 2
Gunzenhausen 2
Islington 2
Las Vegas 2
Los Angeles 2
Montevideo 2
Orsay 2
Pianiga 2
Portland 2
Rovigo 2
Strasbourg 2
Taizhou 2
Torino 2
Yellow Springs 2
Acton 1
Agordo 1
Totale 8.187
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Nome #
4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling 183
The empirical antibiotic treatment of nosocomial spontaneous bacterial peritonitis: Results of a randomized, controlled clinical trial 157
Strategies and methods in monitoring and targeting protein-protein interactions. 152
Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo' 151
A Broad anti-influenza hybrid small molecule that potently disrupts the interaction of polymerase acidic protein-basic protein 1 (PA-PB1) subunits 147
Synthesis and biological evaluation of a library of hybrid derivatives as inhibitors of influenza virus PA-PB1 interaction 146
Antiviral strategies against influenza virus: towards new therapeutic approaches. 144
Drug Repurposing for Viral Infectious Diseases: How Far Are We? 142
Drug Repurposing Approach Identifies Inhibitors of the Prototypic Viral Transcription Factor IE2 that Block Human Cytomegalovirus Replication 136
Early inhibitors of human cytomegalovirus: State-of-art and therapeutic perspectives. 135
Small molecule inhibitors of influenza A and B viruses that act by disrupting subunit interactions of the viral polymerase. 134
Role of homodimerization of human cytomegalovirus DNA polymerase accessory protein UL44 in origin-dependent DNA replication in cells. 134
Simple determination of the HIV protease inhibitor atazanavir in human plasma by high-performance liquid chromatography with UV detection 131
Potent and broad-spectrum cycloheptathiophene-3-carboxamide compounds that target the PA-PB1 interaction of influenza virus RNA polymerase and possess a high barrier to drug resistance 130
The isoquinoline alkaloid berberine inhibits human cytomegalovirus replication by interfering with the viral Immediate Early-2 (IE2) protein transactivating activity 128
Daclatasvir plasma level and resistance selection in HIV patients with hepatitis C virus cirrhosis treated with daclatasvir, sofosbuvir, and ribavirin 125
Development and validation of a simple and robust HPLC method with UV detection for quantification of the hepatitis C virus inhibitor daclatasvir in human plasma 124
Development of a simple HPLC-UV method for the determination of the hepatitis C virus inhibitor simeprevir in human plasma 122
Design, synthesis, and evaluation of WC5 analogues as inhibitors of human cytomegalovirus Immediate-Early 2 protein, a promising target for anti-HCMV treatment. 119
4th European Seminars in Virology on Oncogenic and Oncolytic Viruses, in Bertinoro (Bologna), Italy 119
Identification and Characterization of an Extracellular Protease Activity Produced by the Marine Vibrio sp. 60. 119
Construction of a fusion protein between B subunit of E. coli heat-labile enterotoxin and the C-terminus of herpes simplex virus-DNA polymerase. 117
Optimization of Small-Molecule Inhibitors of Influenza Virus Polymerase: From Thiophene-3-Carboxamide to Polyamido Scaffolds 115
Kinetics of Linezolid in Continuous Renal Replacement Therapy: An in Vitro Study 114
Effect of neutral and acidic phospholipids on mitochondrial ATP synthase secondary structure. 113
Efficient extracellular production of hybrid E. coli heat-labile enterotoxin B subunits in a marine vibrio. 113
The 6-Aminoquinolone WC5 Inhibits Human Cytomegalovirus Replication at an Early Stage by Interfering with the Transactivating Activity of Viral Immediate-Early 2 Protein 112
A point mutation in a herpesvirus polymerase determines neuropathogenicity. 112
The 6-Aminoquinolone WC5 Inhibits Different Functions of the Immediate-Early 2 (IE2) Protein of Human Cytomegalovirus That Are Essential for Viral Replication. 111
Structural investigation of cycloheptathiophene-3-carboxamide derivatives targeting influenza virus polymerase assembly. 111
HPV16 E6 and E7 upregulate the histone lysine demethylase KDM2B through the c-MYC/miR-146a-5p axys 111
Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant 111
The Sp1 transcription factor does not directly interact with the HIV-1 Tat protein 110
Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity 109
Effect of differential growth conditions on the dTTP pool size in herpes simplex virus-infected Vero cells. 108
Structure-Based Optimization of N-Substituted Oseltamivir Derivatives as Potent Anti-Influenza A Virus Agents with Significantly Improved Potency against Oseltamivir-Resistant N1-H274Y Variant 108
Analysis of the Association of the Human Cytomegalovirus DNA Polymerase Subunit UL44 with the Viral DNA Replication Factor UL84 107
The flexible loop of the human cytomegalovirus DNA polymerase processivity factor ppUL44 is required for efficient DNA binding and replication in cells 106
A site-selective hyaluronan-interferonα2a conjugate for the treatment of ovarian cancer 106
A sensitive and validated HPLC-UV method for the quantitative determination of the new antifungal drug isavuconazole in human plasma 103
Separation methods for acyclovir and related antiviral compounds 101
Analysis of the antigen specific T cell repertoires in HIV infection 101
Measurement of ribavirin and evaluation of its stability in human plasma by high-performance liquid chromatography with UV detection 101
Approaches for the generation of new anti-cytomegalovirus agents: identification of protein-protein interaction inhibitors and compounds against the HCMV IE2 protein. 100
Protein-protein interactions as targets for antiviral chemotherapy 98
Specific inhibition of herpes virus replication by receptor-mediated entry of an antiviral peptide linked to Escherichia coli enterotoxin B subunit. 98
1,2,4-Triazolo[1,5-a]pyrimidines: Efficient one-step synthesis and functionalization as influenza polymerase PA-PB1 interaction disruptors 98
A quantitative LumiFluo assay to test inhibitory compounds blocking p53 degradation induced by human papillomavirus oncoprotein E6 in living cells 97
pH-Dependent Conformational Changes and Topology of Herpesvirus Translocating Peptide in a Membrane-Mimetic Enviroment. 96
Identification of new Th peptides from the cytomegalovirus protein pp65 to design a peptide library for generation of CD4 T cell lines for cellular immunoreconstitution 96
Quantitative analysis of ribonucleotide triphosphates in cell extracts by high-performance liquid chromatography and micellar electrokinetic capillary chromatography: a comparative study. 95
Human cytomegalovirus DNA replication: antiviral targets and drugs. 92
Repurposing the clinically approved calcium antagonist manidipine dihydrochloride as a new early inhibitor of human cytomegalovirus targeting the Immediate-Early 2 (IE2) protein 92
The Human Cytomegalovirus DNA Polymerase Processivity Factor UL44 is Modified by SUMO in a DNA-dependent manner 91
Interaction of Sp1 transcription factor with HIV-1 Tatprotein: looking for cellular partners. 90
Inhibition of herpesvirus and influenza virus replication by blocking polymerase subunit interactions 89
Effects of hepatitis C virus infection on the pharmacokinetics of ritonavir-boosted atazanavir in HIV-1-infected patients. 89
Binding parameters and thermodynamics of the interaction of the human cytomegalovirus DNA polymerase accessory protein, UL44, with DNA: implications for the processivity mechanism 89
The catalytic subunit of herpes simplex virus type 1 DNA polymerase contains a nuclear localization signal in the UL42-binding region 88
A 6-Aminoquinolone Compound, WC5, with Potent and Selective Anti-Human Cytomegalovirus Activity 86
How academic labs can approach the drug discovery process as a way to synergize with big pharma 85
EDTA protects E. coli heat-labile enterotoxin B subunit-based fusion proteins from proteolytic degradation during their production by Vibrio spp. 84
Residues of human cytomegalovirus DNA polymerase catalytic subunit, UL54, that are necessary and sufficient for interaction with the accessory protein UL44. 84
Drug Repurposing Campaigns for Human Cytomegalovirus Identify a Natural Compound Targeting the Immediate-Early 2 (IE2) Protein: A Comment on "The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication within Fibroblasts" 82
Unboosted fosamprenavir is associated with low drug exposure in hiv-infected patients with mild-moderate liver impairment for hcv-related cirrhosis. 81
Cloning, expression, and functional characterization of the equine herpesvirus 1 DNA polymerase and its accessory subunit. 80
A novel small-molecule inhibitor of the human papillomavirus E6-p53 interaction that reactivates p53 function and blocks cancer cells growth 80
Efficient and regioselective one-step synthesis of 7-aryl-5-methyl- and 5-aryl-7-methyl-2-amino-[1,2,4]triazolo[1,5-a] pyrimidine derivatives 79
Disruption of protein-protein interactions: towards new targets for chemotherapy. 78
Use of Vibrio spp. for expression of E. coli enterotoxin B subunit fusion proteins: purification and characterization of a chimera containing a C-terminal fragment of DNA polymerase from herpes virus type 1. 77
Multiple Phosphorylation Sites at the C-terminus Regulate Nuclear Import of HCMV DNA Polymerase Processivity Factor ppUL44. 76
The Carboxy-Terminal Segment of the Human Cytomegalovirus DNA Polymerase Accessory Subunit UL44 Is Crucial for Viral Replication 75
Quantitative analysis of ribonucleoside triphosphates (rNTPs) in human lymphoid cells by micellar electrokinetic capillary chromatography (MECC). 75
The cytomegalovirus DNA polymerase subunit UL44 forms a C-clamp shaped dimer. 73
The antifungal drug isavuconazole inhibits the replication of human cytomegalovirus (HCMV) and acts synergistically with anti-HCMV drugs 73
Human CD4 T-cell repertoires specific for opportunistic pathogens. 70
Sulfated Derivatives of Escherichia coli K5 Polysaccharide are Potent Inhibitors of Human Cytomegalovirus. 70
Corrigendum to “Exploring the cycloheptathiophene-3-carboxamide scaffold to disrupt the interactions of the influenza polymerase subunits and obtain potent anti-influenza activity” [Eur. J. Med. Chem. 138 (2017) 128–139] (S0223523417304610) (10.1016/j.ejmech.2017.06.015)) 70
Regulated Transport into the Nucleus of Herpesviridae DNA Replication Core Proteins 68
Peptide inhibition of HCMV DNA polymerase processivity 66
Crystal structure of the B subunit of Escherichia coli heat-labile enterotoxin carrying peptides with anti-herpes simplex virus type 1 activity. 66
Human Cytomegalovirus Inhibitor AL18 Also Possesses Activity against Influenza A and B Viruses. 64
Selective anti-cytomegalovirus compounds discovered by screening for inhibitors of subunit interactions of the viral polymerase 63
Antiviral properties of new arylsulfone derivatives with activity against human betaherpesviruses 62
CD4 and CD8 epitope mapping of cytomegalovirus tegument protein pp65 for diagnostic, vaccinal and therapeutic purposes. 59
Disruption of the interactions between the subunits of herpesvirus DNA polymerases as a novel antiviral strategy. 58
Discovery of highly potent and selective influenza virus neuraminidase inhibitors targeting 150-cavity 58
The Clinically Approved Antifungal Drug Posaconazole Inhibits Human Cytomegalovirus Replication 57
Synthesis and characterization of 1,2,4-triazolo[1,5-a]pyrimidine-2-carboxamide-based compounds targeting the PA-PB1 interface of influenza A virus polymerase 56
Specific residues in the connector loop of the human cytomegalovirus DNA polymerase accessory protein, UL44, are crucial for interaction with the UL54 catalytic subunit. 56
The dimeric form of hpv16 e6 is crucial to drive yap/taz upregulation through the targeting of hscrib 53
Crystal structure of the cytomegalovirus DNA polymerase subunit UL44 in complex with the C terminus from the catalytic subunit - Differences in structure and function relative to unliganded UL44 47
Author Correction: Suppression of a SARS-CoV-2 outbreak in the Italian municipality of Vo’ (Nature, (2020), 584, 7821, (425-429), 10.1038/s41586-020-2488-1) 47
Divide et impera: An In Silico Screening Targeting HCMV ppUL44 Processivity Factor Homodimerization Identifies Small Molecules Inhibiting Viral Replication 46
Intranuclear delivery of an anti-HSV-1 peptide mediated by the B-subunit of cholera-like toxin. 44
Indomethacin-based PROTACs as pan-coronavirus antiviral agents 44
Ethyl1,8-Naphthyridone-3-carboxylates Downregulate HPV-16 E6 and E7 Oncogenes Expression 41
Antiviral methods and compositions 33
Targeted disruption of e6/p53 binding exerts broad activity and synergism with paclitaxel and topotecan against hpv-transformed cancer cells 31
Identification of C5-NH2 Modified Oseltamivir Derivatives as Novel Influenza Neuraminidase Inhibitors with Highly Improved Antiviral Activities and Favorable Druggability 30
Totale 9.403
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Categoria #
all - tutte 32.564
article - articoli 31.179
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 182
patent - brevetti 318
selected - selezionate 0
volume - volumi 664
Totale 64.907
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019696 0 0 0 0 0 0 0 0 0 148 303 245
2019/20202.414 230 59 40 392 278 206 262 272 289 178 137 71
2020/20211.394 95 92 67 92 48 83 62 140 209 129 191 186
2021/20221.668 37 152 203 153 118 101 80 208 54 55 174 333
2022/20231.410 252 141 34 160 223 224 4 104 139 34 74 21
2023/2024778 24 116 145 56 83 74 109 54 18 99 0 0
Totale 9.673