BORTOLOZZI, ROBERTA
BORTOLOZZI, ROBERTA
Dipartimento di Scienze del Farmaco - DSF
3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization
2018 Romagnoli, Romeo; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; Baraldi, Pier Giovanni; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Bortolozzi, Roberta; Viola, Giampietro
9-(4-Dimethylaminophenyl)benzo[b]quinolizinium: A Near-Infrared Fluorophore for the Multicolor Analysis of Proteins and Nucleic Acids in Living Cells
2013 Bortolozzi, Roberta; Heiko, Ihmels; Laura, Thomas; Maoqun, Tian; Viola, Giampietro
A facile synthesis of diaryl pyrroles led to the discovery of potent colchicine site antimitotic agents
2021 Romagnoli, R.; Oliva, P.; Salvador, M. K.; Manfredini, S.; Padroni, C.; Brancale, A.; Ferla, S.; Hamel, E.; Ronca, R.; Maccarinelli, F.; Rruga, F.; Mariotto, E.; Viola, G.; Bortolozzi, R.
A Multi-Omics Approach Reveals Enrichment in Metabolites Involved in the Regulation of the Glutathione Pathway in LIN28B-Dependent Cancer Cells
2024 Stocchero, Matteo; Corallo, Diana; Bresolin, Silvia; Pantile, Marcella; Pirillo, Paola; Bortolozzi, Roberta; Menegazzo, Sara; Boso, Daniele; Viola, Giampietro; Baraldi, Eugenio; Biffi, Alessandra; Giordano, Giuseppe; Aveic, Sanja
A novel copper(I) complex induces ER-stress-mediated apoptosis and sensitizes B-acute lymphoblastic leukemia cells to chemotherapeutic agents
2014 Bortolozzi, Roberta; Viola, G.; Porcù, E.; Consolaro, Francesca; Marzano, Cristina; Pellei, M.; Gandin, Valentina; Basso, Giuseppe
AKR1C enzymes sustain therapy resistance in paediatric T-ALL
2018 Bortolozzi, Roberta; Bresolin, Silvia; Rampazzo, Elena; Paganin, Maddalena; Maule, Francesca; Mariotto, Elena; Boso, Daniele; Minuzzo, Sonia; Agnusdei, Valentina; Viola, Giampietro; Te Kronnie, Geertruy; Cazzaniga, Giovanni; Basso, Giuseppe; Persano, Luca
Choline kinase alpha inhibition by EB-3D triggers cellular senescence, reduces tumor growth and metastatic dissemination in breast cancer
2018 Mariotto, Elena; Viola, Giampietro; Ronca, Roberto; Persano, Luca; Aveic, Sanja; Bhujwalla, Zaver M.; Mori, Noriko; Accordi, Benedetta; Serafin, Valentina; López-Cara, Luisa Carlota; Bortolozzi, Roberta
Cinnamic acid derivatives linked to arylpiperazines as novel potent inhibitors of tyrosinase activity and melanin synthesis
2022 Romagnoli, R.; Oliva, P.; Prencipe, F.; Manfredini, S.; Germano, M. P.; De Luca, L.; Ricci, F.; Corallo, D.; Aveic, S.; Mariotto, E.; Viola, G.; Bortolozzi, R.
Complementary isonitrile-based multicomponent reactions for the synthesis of diversified cytotoxic hemiasterlin analogues
2015 Lesma, Giordano; Bassanini, Ivan; Bortolozzi, Roberta; Colletto, Chiara; Bai, Ruoli; Hamel, Ernest; Meneghetti, Fiorella; Rainoldi, Giulia; Stucchi, Mattia; Sacchetti, Alessandro; Silvani, Alessandra; Viola, Giampietro
Concise Synthesis and Biological Evaluation of 2-Aroyl-5-Amino Benzo[ b ]thiophene Derivatives As a Novel Class of Potent Antimitotic Agents
2013 Romagnoli, Romeo; Baraldi, Pier Giovanni; Lopez-Cara, Carlota; Preti, Delia; Aghazadeh Tabrizi, Mojgan; Balzarini, Jan; Bassetto, Marcella; Brancale, Andrea; Fu, Xian-Hua; Gao, Yang; Li, Jun; Zhang, Su-Zhan; Hamel, Ernest; Bortolozzi, Roberta; Basso, Giuseppe; Viola, Giampietro
Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents
2021 Romagnoli, R.; Preti, D.; Hamel, E.; Bortolozzi, R.; Viola, G.; Brancale, A.; Ferla, S.; Morciano, G.; Pinton, P.
Design and synthesis of potent in vitro and in vivo anticancer agents based on 1-(3',4',5'-trimethoxyphenyl)-2-Aryl-1H-imidazole
2016 Romagnoli, Romeo; Baraldi, Pier Giovanni; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; Tabrizi, Mojgan Aghazadeh; Lopez-Cara, Luisa Carlota; Ferla, Salvatore; Brancale, Andrea; Hamel, Ernest; Ronca, Roberto; Bortolozzi, Roberta; Mariotto, Elena; Basso, Giuseppe; Viola, Giampietro
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization
2020 Romagnoli, R.; Prencipe, F.; Oliva, P.; Kimatrai Salvador, M.; Brancale, A.; Ferla, S.; Hamel, E.; Viola, G.; Bortolozzi, R.; Persoons, L.; Balzarini, J.; Liekens, S.; Schols, D.
Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents
2015 Romagnoli, Romeo; Baraldi, Pier Giovanni; Lopez-Cara, Carlota; Salvador, Maria Kimatrai; Preti, Delia; Tabrizi, Mojgan Aghazadeh; Balzarini, Jan; Nussbaumer, Peter; Bassetto, Marcella; Brancale, Andrea; Fu, Xian-Hua; Yang-Gao, Null; Li, Jun; Zhang, Su-Zhan; Hamel, Ernest; Bortolozzi, Roberta; Basso, Giuseppe; Viola, Giampietro
Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents.
2013 Romagnoli, R; Baraldi, Pg; Lopez Cara, C; Salvador, Mk; Preti, D; Tabrizi, Ma; Balzarini, J; Nussbaumer, P; Bassetto, M; Brancale, A; Fu, Xh; Yang, Gao; Li, J; Zhang, Sz; Hamel, E; Bortolozzi, Roberta; Basso, Giuseppe; Viola, G.
Design, synthesis and biological evaluation of 3-substituted-2-oxindole hybrid derivatives as novel anticancer agents
2017 Romagnoli, Romeo; Baraldi, Pier Giovanni; Prencipe, Filippo; Oliva, Paola; Baraldi, Stefania; Salvador, Maria Kimatrai; Lopez-Cara, Luisa Carlota; Bortolozzi, Roberta; Mattiuzzo, Elena; Basso, Giuseppe; Viola, Giampietro
Design, synthesis and biological evaluation of novel vicinal diaryl-substituted 1H-Pyrazole analogues of combretastatin A-4 as highly potent tubulin polymerization inhibitors
2019 Romagnoli, R.; Oliva, P.; Salvador, M. K.; Camacho, M. E.; Padroni, C.; Brancale, A.; Ferla, S.; Hamel, E.; Ronca, R.; Grillo, E.; Bortolozzi, R.; Rruga, F.; Mariotto, E.; Viola, G.
Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities
2022 Romagnoli, Romeo; Oliva, Paola; Prencipe, Filippo; Manfredini, Stefano; Budassi, Federica; Brancale, Andrea; Ferla, Salvatore; Hamel, Ernest; Corallo, Diana; Aveic, Sanja; Manfreda, Lorenzo; Mariotto, Elena; Bortolozzi, Roberta; Viola, Giampietro
Design, Synthesis, and Biological Evaluation of 6-Substituted Thieno[3,2- d]pyrimidine Analogues as Dual Epidermal Growth Factor Receptor Kinase and Microtubule Inhibitors
2019 Romagnoli, R.; Prencipe, F.; Oliva, P.; Baraldi, S.; Baraldi, P. G.; Schiaffino Ortega, S.; Chayah, M.; Kimatrai Salvador, M.; Lopez-Cara, L. C.; Brancale, A.; Ferla, S.; Hamel, E.; Ronca, R.; Bortolozzi, R.; Mariotto, E.; Mattiuzzo, E.; Viola, G.
Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold
2023 Romagnoli, Romeo; De Ventura, Tiziano; Manfredini, Stefano; Baldini, Erika; Supuran, Claudiu T; Nocentini, Alessio; Brancale, Andrea; Bortolozzi, Roberta; Manfreda, Lorenzo; Viola, Giampietro