GIORGIO, MARCO
 Distribuzione geografica
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Continente #
NA - Nord America 6.426
AS - Asia 1.578
EU - Europa 614
AF - Africa 126
SA - Sud America 122
OC - Oceania 3
Totale 8.869
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Nazione #
US - Stati Uniti d'America 6.423
CN - Cina 674
SG - Singapore 615
VN - Vietnam 172
IT - Italia 144
CI - Costa d'Avorio 121
BR - Brasile 118
FI - Finlandia 92
HK - Hong Kong 85
DE - Germania 79
PL - Polonia 61
SE - Svezia 47
GB - Regno Unito 37
FR - Francia 36
RU - Federazione Russa 33
UA - Ucraina 25
AT - Austria 17
IE - Irlanda 15
NL - Olanda 14
IN - India 12
AE - Emirati Arabi Uniti 5
HU - Ungheria 4
CZ - Repubblica Ceca 3
TR - Turchia 3
CA - Canada 2
NZ - Nuova Zelanda 2
PK - Pakistan 2
ZA - Sudafrica 2
AM - Armenia 1
AR - Argentina 1
AU - Australia 1
BD - Bangladesh 1
DK - Danimarca 1
EC - Ecuador 1
EG - Egitto 1
ES - Italia 1
HN - Honduras 1
IQ - Iraq 1
IR - Iran 1
JO - Giordania 1
JP - Giappone 1
KE - Kenya 1
KZ - Kazakistan 1
LT - Lituania 1
LV - Lettonia 1
NO - Norvegia 1
NP - Nepal 1
OM - Oman 1
PE - Perù 1
PH - Filippine 1
PT - Portogallo 1
RO - Romania 1
TN - Tunisia 1
VE - Venezuela 1
Totale 8.869
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Città #
Fairfield 1.455
Woodbridge 674
Ashburn 584
Houston 522
Cambridge 505
Seattle 495
Wilmington 375
Singapore 297
Ann Arbor 247
Boardman 190
Chandler 188
Dong Ket 172
Beijing 165
Princeton 154
Medford 134
San Diego 132
Abidjan 121
Des Moines 108
Nanjing 94
Hong Kong 83
Jacksonville 69
Helsinki 65
Bytom 59
Jinan 58
Roxbury 55
Santa Clara 54
Shenyang 44
Padova 31
Nanchang 26
Hebei 25
Ningbo 24
Hefei 20
Zhengzhou 20
Guangzhou 19
Changsha 17
Dublin 15
London 13
Dearborn 12
Lanzhou 12
Milan 11
Nuremberg 11
Tianjin 11
Kharkiv 10
Pune 10
Haikou 9
Jiaxing 9
Taiyuan 9
Vienna 9
Rome 8
Lappeenranta 7
Redwood City 7
Shanghai 7
Sommacampagna 7
São Paulo 7
Borås 6
Fuzhou 6
Hangzhou 6
Kilburn 6
Norwalk 6
Dubai 5
Guarulhos 5
Kunming 5
Rio de Janeiro 5
Selvazzano Dentro 5
Budapest 4
Chicago 4
Parma 4
Villafranca Padovana 4
Barzago 3
Belo Horizonte 3
Chengdu 3
Chiswick 3
Chongqing 3
Ogden 3
Paese 3
Revere 3
Sorocaba 3
Urbino 3
Washington 3
Alegrete 2
Atrani 2
Betim 2
Campinas 2
Castel San Pietro Terme 2
Düsseldorf 2
Fagnano Olona 2
Frankfurt am Main 2
Gricignano di Aversa 2
Hounslow 2
Hradec Králové 2
Ilhéus 2
Indiana 2
Istanbul 2
Los Angeles 2
Maserà di Padova 2
Montes Claros 2
Munich 2
New Bedfont 2
Paris 2
Praia Grande 2
Totale 7.611
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Nome #
Diabetes-associated myelopoiesis drives stem cell mobilopathy through an OSM-p66Shc signaling pathway 176
1. Novel neuroferritinopathy mouse model (ftl 498instc) shows progressive brain iron dysregulation, morphological signs of early neurodegeneration and motor coordination deficits 167
p66Shc deletion or deficiency protects from obesity but not metabolic dysfunction in mice and humans 151
Diabetes causes bone marrow autonomic neuropathy and impairs stem cell mobilization via dysregulated p66Shc and Sirt1 134
The cellular prion protein counteracts cardiac oxidative stress 130
The p66(Shc) redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells. 122
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis 121
The p66ShcA adaptor protein regulates healing after myocardial infarction 118
New aspects of p66Shc in ischaemia reperfusion injury and other cardiovascular diseases 116
Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66 Shc transcription and vascular oxidative stress in obesity 115
Ablation of the gene encoding p66(Shc) protects mice against AGE-induced glomerulopathy by preventing oxidant-dependent tissue injury and further AGE accumulation 113
A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis 112
p66(Shc)-generated Oxidative Signal Promotes Fat Accumulation 111
The Redox Enzyme p66Shc Contributes to Diabetes and Ischemia-Induced Delay in Cutaneous Wound Healing 110
The p53-p66Shc apoptotic pathway is dispensable for tumor suppression whereas the p66Shc-generated oxidative stress initiates tumorigenesis. 109
Therapeutic synergy between tigecycline and venetoclax in a preclinical model of MYC/BCL2 double-hit B cell lymphoma 104
Sustained hippocampal neurogenesis in females is amplified in P66(Shc-/-) mice: An animal model of healthy aging 102
Medullary thyroid carcinomas in transgenic mice expressing a polyoma carboxyl-terminal truncated middle-T and wild type small-T antigens 95
Hematopoietic and Nonhematopoietic p66Shc Differentially Regulates Stem Cell Traffic and Vascular Response to Ischemia in Diabetes 95
Angiogenesis inhibition by the maleimide-based small molecule GNX-686 94
Circulating Cytochrome c as Potential Biomarker of Impaired Reperfusion in ST-Segment Elevation Acute Myocardial Infarction 92
Apoptosis and aging: Role of p66(Shc) Redox protein 92
Blood orange juice inhibits fat accumulation in mice 91
The cardioprotective effects elicited by p66(Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury 90
Alternative Forms and Functions of the c-kit Receptor and Its Ligand During Spermatogenesis 90
Null Mutations at the p66 and Bradykinin 2 Receptor Loci Induce Divergent Phenotypes in the Diabetic Kidney 90
Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66(Shc) and monoamine oxidase 89
The Shc locus regulates insulin signaling and adiposity in mammals 89
Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors 89
Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66(Shc) 88
Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation 88
Gene rearrangements in the molecular pathogenesis of acute promyelocytic leukemia 88
Genetic inactivation of the p66 isoform of ShcA is neuroprotective in a murine model of multiple sclerosis 86
Deletion of p66(Shc) longevity gene protects against experimental diabetic glomerulopathy by preventing diabetes-induced oxidative stress 86
Deletion of the life span determinant p66(Shc) prevents age-dependent increases in emotionality and pain sensitivity in mice 85
Electrochemical study of hydrogen peroxide formation in isolated mitochondria 85
Deletion of the p66(Shc) longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet 85
The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential 84
p66Shc Deletion Confers Vascular Protection in Advanced Atherosclerosis in Hypercholesterolemic Apolipoprotein E Knockout Mice 84
Moro orange juice prevents fatty liver in mice 84
p66(ShcA) modulates tissue response to hindlimb ischemia 83
Deletion of the lifespan determinant p66(Shc) improves performance in a spatial memory task, decreases levels of oxidative stress markers in the hippocampus and increases levels of the neurotrophin BDNF in adult mice 82
Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals? 82
Greater resistance to inflammation at adulthood could contribute to extended life span of p66(Shc-/-) mice 82
Decreased Superoxide Production in Macrophages of Long-lived p66Shc Knock-out Mice 81
Microdrawing and highlighting a reactive surface 78
In S. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase 78
Regulatory effects of the mitochondrial energetic status on mitochondrial p66(Shc) 78
Mitochondria and vascular pathology 76
Mitochondrial DNA copy number is regulated by cellular proliferation: A role for Ras and p66 (Shc) 75
On the epigenetic role of guanosine oxidation 75
Electrochemical Detection of H2O2 Formation in Isolated Mitochondria. 72
The Determining Role of Mitochondrial Reactive Oxygen Species Generation and Monoamine Oxidase Activity in Doxorubicin-Induced Cardiotoxicity 71
Cyanidin-3-O-β-glucoside and protocatechuic acid activate AMPK/mTOR/S6K pathway and improve glucose homeostasis in mice 69
Oxidative stress and the unfulfilled promises of antioxidant agents 69
Phosphorylation of p66Shc Downregulates PMCA4a and Sensitizes T Cells to Ca2+ Deregulation, Mitochondrial Dysfunction and Apoptosis 68
Cyclophilin D counteracts P53-mediated growth arrest and promotes Ras tumorigenesis. 68
Modelling the p53/p66Shc aging pathway in the shortest living vertebrate Nothobranchius Furzeri 68
Glucose and Lactate Miniaturized Biosensors for SECM-Based High-Spatial Resolution Analysis: A Comparative Study 68
The Influence of Shc Proteins on Life Span in Mice 65
Genetic ablation of p66(Shc) rescues functional and morphological abnormalities in collagen VI dystrophic mice 64
Inhibition of monoamine oxidases reduces doxorubicin-induced cardiomyocyte death 64
Novel insights into the PKCβ-dependent regulation of the oxidoreductase p66Shc 64
P66SHC deletion improves fertility and progeric phenotype of late-generation TERC-deficient mice but not their short lifespan 62
New aspects of p66Shc in ischemia reperfusion injury and cardiovascular diseases 61
SATURATION MUTAGENESIS OF THE HUMAN INTERLEUKIN-6 RECEPTOR-BINDING SITE - IMPLICATIONS FOR ITS 3-DIMENSIONAL STRUCTURE 60
Dietary cyanidin 3-glucoside from purple corn ameliorates doxorubicin-induced cardiotoxicity in mice 60
Scanning electro-chemical microscopy reveals cancer cell redox state 59
The p66Shc knocked out mice are short lived under natural condition 57
Maternal care determinant of longevity? 57
The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas 57
Isolation stress affects tumor progression through a BDNF-neuroendocrine axis in a mouse model of breast cancer 56
Epigenomic profiling of archived FFPE tissues by enhanced PAT-ChIP (EPAT-ChIP) technology 54
On the epigenetic role of guanosine oxidation 54
p66(shc) and oxidative stress induced by post-ischemic reperfusion injury 52
Inhibition of the Histone Demethylase LSD1 Combined with Caloric Restriction or IGF1/Insulin Inhibition Leads to Durable Responses in a Preclinical Model of Acute Myeloid Leukemia 52
The P66Shc/Mitochondrial Permeability Transition Pore Pathway Determines Neurodegeneration 51
Cardiac Stem Cells and the Diabetic Cardiomyopathy 50
Low oxygen tension maintains multipotency, whereas normoxia increases differentiation of mouse bone marrow stromal cells 50
THE OXIDATIVE STRESS RESPONSE GENE P66 SHC AND THE TUMOR SUPPRESSOR GENE P53 INDUCE MITOCHONDRIAL DNA DAMAGES 50
Comparative analysis of histone h3k4me3 distribution in mouse liver in different diets reveals the epigenetic efficacy of cyanidin-3-o-glucoside dietary intake 50
Deletion of the redox enzyme p66shc promotes diabetic wound healing in mice 49
Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging 49
Ras-dependent carbon metabolism and transformation in mouse broblasts 48
Metabolic Constrains Rule Metastasis Progression 47
DEVELOPMENT OF PROGRESSIVE KIDNEY DAMAGE AND MYELOMA KIDNEY IN INTERLEUKIN-6 TRANSGENIC MICE 46
Mouse models and Longevity 46
A PROMOTER WITHIN AN INTRON OF THE MOUSE C-KIT RECEPTOR GENE, DRIVES THE TRANSCRIPTION OF A TRUNCATED FORM OF THE RECEPTOR IN LATE SPERMIOGENESIS 46
Diabetes promotes cardiac stem cell aging and heart failure, which are prevented by deletion of the p66(shc) gene 46
The Other Face of ROS: a Driver of Stem Cell Expansion in Colorectal Cancer. 45
Deletion of p66Shc in mice increases the frequency of size-change mutations in the lacZ transgene 44
A Role for PML in Innate Immunity 43
Insights into the beneficial effect of caloric/ dietary restriction for a healthy and prolonged life 43
Crucial role of p66ShcA in tissue damage induced by hindlimb ischaemia 43
P66(Shc), redox signaling and aging 41
P66ShcA adaptor protein facilitates heart rupture via activation of MMP-2 in an in vivo model of myocardial infarction in mice 41
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Histone H3 Lysine 4 and 27 Trimethylation Landscape of Human Alzheimer’s Disease 41
A cell- and developmental stage-specific promoter drives the expression of a truncated c-kit protein during mouse spermatid elongation 40
Materials and methods relating to modulation of p66 expression 38
Totale 7.659
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Categoria #
all - tutte 39.439
article - articoli 37.724
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 242
selected - selezionate 0
volume - volumi 1.061
Totale 78.466
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020314 0 0 0 0 0 0 0 0 0 0 238 76
2020/20211.661 158 125 187 47 33 71 43 181 197 191 163 265
2021/20221.616 43 202 182 116 65 52 82 159 87 43 218 367
2022/2023636 255 33 25 50 82 63 5 27 47 9 29 11
2023/2024462 6 28 30 38 21 47 55 39 14 16 80 88
2024/20251.510 10 90 58 38 251 48 118 203 337 112 245 0
Totale 9.074