GIORGIO, MARCO
 Distribuzione geografica
Continente #
NA - Nord America 5766
AS - Asia 735
EU - Europa 296
OC - Oceania 2
Totale 6799
Nazione #
US - Stati Uniti d'America 5764
CN - Cina 558
VN - Vietnam 172
FI - Finlandia 81
IT - Italia 60
SE - Svezia 47
DE - Germania 40
UA - Ucraina 23
IE - Irlanda 15
GB - Regno Unito 9
FR - Francia 8
RU - Federazione Russa 6
NL - Olanda 5
CA - Canada 2
NZ - Nuova Zelanda 2
TR - Turchia 2
AE - Emirati Arabi Uniti 1
AT - Austria 1
DK - Danimarca 1
IN - India 1
JO - Giordania 1
Totale 6799
Città #
Fairfield 1445
Woodbridge 671
Ashburn 540
Houston 518
Cambridge 501
Seattle 491
Wilmington 373
Ann Arbor 247
Chandler 186
Dong Ket 172
Princeton 154
Medford 134
San Diego 131
Beijing 122
Des Moines 108
Nanjing 94
Jacksonville 69
Helsinki 62
Jinan 58
Roxbury 55
Shenyang 44
Boardman 29
Hebei 25
Nanchang 25
Padova 25
Ningbo 24
Hefei 20
Zhengzhou 20
Changsha 17
Dublin 15
Dearborn 12
Lanzhou 12
Guangzhou 11
Tianjin 11
Kharkiv 10
Haikou 9
Jiaxing 9
Taiyuan 9
Redwood City 7
Sommacampagna 7
Borås 6
Fuzhou 6
Hangzhou 6
Norwalk 6
Kunming 5
Selvazzano Dentro 5
London 4
Milan 3
Shanghai 3
Urbino 3
Chengdu 2
Chicago 2
Chongqing 2
Indiana 2
Istanbul 2
Munich 2
Shaoxing 2
Taizhou 2
Xian 2
Amman 1
Bergamo 1
Brooklyn 1
Castegnero 1
Castel Maggiore 1
Dubai 1
Geislingen an der Steige 1
Jinhua 1
Kazan 1
Las Vegas 1
Latina 1
Maykop 1
Milton Keynes 1
Monmouth Junction 1
Nanning 1
Orange 1
Pavia 1
Pinehaven 1
Qingdao 1
Quzhou 1
Vienna 1
Volga 1
Volgograd 1
Wellington 1
Wenzhou 1
Totale 6562
Nome #
1. Novel neuroferritinopathy mouse model (ftl 498instc) shows progressive brain iron dysregulation, morphological signs of early neurodegeneration and motor coordination deficits 150
Diabetes-associated myelopoiesis drives stem cell mobilopathy through an OSM-p66Shc signaling pathway 142
p66Shc deletion or deficiency protects from obesity but not metabolic dysfunction in mice and humans 121
Diabetes causes bone marrow autonomic neuropathy and impairs stem cell mobilization via dysregulated p66Shc and Sirt1 110
The p66(Shc) redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells. 110
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis 109
The cellular prion protein counteracts cardiac oxidative stress 109
New aspects of p66Shc in ischaemia reperfusion injury and other cardiovascular diseases 103
The p66ShcA adaptor protein regulates healing after myocardial infarction 102
Ablation of the gene encoding p66(Shc) protects mice against AGE-induced glomerulopathy by preventing oxidant-dependent tissue injury and further AGE accumulation 101
p66(Shc)-generated Oxidative Signal Promotes Fat Accumulation 99
The p53-p66Shc apoptotic pathway is dispensable for tumor suppression whereas the p66Shc-generated oxidative stress initiates tumorigenesis. 99
The Redox Enzyme p66Shc Contributes to Diabetes and Ischemia-Induced Delay in Cutaneous Wound Healing 95
Sustained hippocampal neurogenesis in females is amplified in P66(Shc-/-) mice: An animal model of healthy aging 93
Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66 Shc transcription and vascular oxidative stress in obesity 91
Medullary thyroid carcinomas in transgenic mice expressing a polyoma carboxyl-terminal truncated middle-T and wild type small-T antigens 83
A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis 82
Deletion of p66(Shc) longevity gene protects against experimental diabetic glomerulopathy by preventing diabetes-induced oxidative stress 81
Null Mutations at the p66 and Bradykinin 2 Receptor Loci Induce Divergent Phenotypes in the Diabetic Kidney 81
Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66(Shc) and monoamine oxidase 80
Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation 80
Apoptosis and aging: Role of p66(Shc) Redox protein 79
Electrochemical study of hydrogen peroxide formation in isolated mitochondria 79
Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66(Shc) 78
The cardioprotective effects elicited by p66(Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury 78
p66Shc Deletion Confers Vascular Protection in Advanced Atherosclerosis in Hypercholesterolemic Apolipoprotein E Knockout Mice 78
Angiogenesis inhibition by the maleimide-based small molecule GNX-686 77
The Shc locus regulates insulin signaling and adiposity in mammals 77
The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential 77
Gene rearrangements in the molecular pathogenesis of acute promyelocytic leukemia 77
Greater resistance to inflammation at adulthood could contribute to extended life span of p66(Shc-/-) mice 77
Deletion of the life span determinant p66(Shc) prevents age-dependent increases in emotionality and pain sensitivity in mice 76
Circulating Cytochrome c as Potential Biomarker of Impaired Reperfusion in ST-Segment Elevation Acute Myocardial Infarction 76
Blood orange juice inhibits fat accumulation in mice 76
Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors 75
Moro orange juice prevents fatty liver in mice 75
p66(ShcA) modulates tissue response to hindlimb ischemia 74
Deletion of the lifespan determinant p66(Shc) improves performance in a spatial memory task, decreases levels of oxidative stress markers in the hippocampus and increases levels of the neurotrophin BDNF in adult mice 74
Genetic inactivation of the p66 isoform of ShcA is neuroprotective in a murine model of multiple sclerosis 74
Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals? 74
Deletion of the p66(Shc) longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet 74
Decreased Superoxide Production in Macrophages of Long-lived p66Shc Knock-out Mice 73
Microdrawing and highlighting a reactive surface 70
Therapeutic synergy between tigecycline and venetoclax in a preclinical model of MYC/BCL2 double-hit B cell lymphoma 70
Alternative Forms and Functions of the c-kit Receptor and Its Ligand During Spermatogenesis 69
Regulatory effects of the mitochondrial energetic status on mitochondrial p66(Shc) 69
Mitochondrial DNA copy number is regulated by cellular proliferation: A role for Ras and p66 (Shc) 68
Mitochondria and vascular pathology 67
Electrochemical Detection of H2O2 Formation in Isolated Mitochondria. 64
Phosphorylation of p66Shc Downregulates PMCA4a and Sensitizes T Cells to Ca2+ Deregulation, Mitochondrial Dysfunction and Apoptosis 57
Cyclophilin D counteracts P53-mediated growth arrest and promotes Ras tumorigenesis. 55
Modelling the p53/p66Shc aging pathway in the shortest living vertebrate Nothobranchius Furzeri 55
P66SHC deletion improves fertility and progeric phenotype of late-generation TERC-deficient mice but not their short lifespan 53
SATURATION MUTAGENESIS OF THE HUMAN INTERLEUKIN-6 RECEPTOR-BINDING SITE - IMPLICATIONS FOR ITS 3-DIMENSIONAL STRUCTURE 52
The Influence of Shc Proteins on Life Span in Mice 50
Cyanidin-3-O-β-glucoside and protocatechuic acid activate AMPK/mTOR/S6K pathway and improve glucose homeostasis in mice 50
Oxidative stress and the unfulfilled promises of antioxidant agents 50
The p66Shc knocked out mice are short lived under natural condition 49
Scanning electro-chemical microscopy reveals cancer cell redox state 49
New aspects of p66Shc in ischemia reperfusion injury and cardiovascular diseases 49
Novel insights into the PKCβ-dependent regulation of the oxidoreductase p66Shc 49
Glucose and Lactate Miniaturized Biosensors for SECM-Based High-Spatial Resolution Analysis: A Comparative Study 49
Hematopoietic and non-hematopoietic p66Shc differentially regulates stem cell traffic and vascular response to ischemia in diabetes 48
p66(shc) and oxidative stress induced by post-ischemic reperfusion injury 47
Isolation stress affects tumor progression through a BDNF-neuroendocrine axis in a mouse model of breast cancer 47
On the epigenetic role of guanosine oxidation 43
Ras-dependent carbon metabolism and transformation in mouse broblasts 42
The P66Shc/Mitochondrial Permeability Transition Pore Pathway Determines Neurodegeneration 42
THE OXIDATIVE STRESS RESPONSE GENE P66 SHC AND THE TUMOR SUPPRESSOR GENE P53 INDUCE MITOCHONDRIAL DNA DAMAGES 42
Epigenomic profiling of archived FFPE tissues by enhanced PAT-ChIP (EPAT-ChIP) technology 42
Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging 41
Low oxygen tension maintains multipotency, whereas normoxia increases differentiation of mouse bone marrow stromal cells 41
null 41
Inhibition of the Histone Demethylase LSD1 Combined with Caloric Restriction or IGF1/Insulin Inhibition Leads to Durable Responses in a Preclinical Model of Acute Myeloid Leukemia 40
DEVELOPMENT OF PROGRESSIVE KIDNEY DAMAGE AND MYELOMA KIDNEY IN INTERLEUKIN-6 TRANSGENIC MICE 39
Dietary cyanidin 3-glucoside from purple corn ameliorates doxorubicin-induced cardiotoxicity in mice 39
Mouse models and Longevity 38
Maternal care determinant of longevity? 38
Insights into the beneficial effect of caloric/ dietary restriction for a healthy and prolonged life 37
The Other Face of ROS: a Driver of Stem Cell Expansion in Colorectal Cancer. 37
In S. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase 37
Diabetes promotes cardiac stem cell aging and heart failure, which are prevented by deletion of the p66(shc) gene 37
Genetic ablation of p66(Shc) rescues functional and morphological abnormalities in collagen VI dystrophic mice 36
Deletion of p66Shc in mice increases the frequency of size-change mutations in the lacZ transgene 36
Cardiac Stem Cells and the Diabetic Cardiomyopathy 35
P66(Shc), redox signaling and aging 35
The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas 35
The Determining Role of Mitochondrial Reactive Oxygen Species Generation and Monoamine Oxidase Activity in Doxorubicin-Induced Cardiotoxicity 35
Inhibition of monoamine oxidases reduces doxorubicin-induced cardiomyocyte death 34
Crucial role of p66ShcA in tissue damage induced by hindlimb ischaemia 33
A PROMOTER WITHIN AN INTRON OF THE MOUSE C-KIT RECEPTOR GENE, DRIVES THE TRANSCRIPTION OF A TRUNCATED FORM OF THE RECEPTOR IN LATE SPERMIOGENESIS 32
Metabolic Constrains Rule Metastasis Progression 31
Deletion of the redox enzyme p66shc promotes diabetic wound healing in mice 29
RECOGNITION EFFICIENCY OF THE HEPATITIS-B VIRUS POLYADENYLATION SIGNALS IS TISSUE SPECIFIC IN TRANSGENIC MICE 29
P66ShcA adaptor protein facilitates heart rupture via activation of MMP-2 in an in vivo model of myocardial infarction in mice 29
The p66(shc) adaptor protein controls oxidative stress response and life span in mammals 27
A Role for PML in Innate Immunity 25
6. PROBING OXYGEN METABOLISM IN TUMOUR AND NORMAL LIVING CELLS BY SCANNING ELECTROCHEMICAL MICROSCOPY. 25
Ablation of the p66(Shc) longevity gene provides protection towards experimental diabetic glomerulopathy in mice 25
Diagnostic and Prognostic Utility of Circulating Cytochrome c in Acute Myocardial Infarction 25
Totale 6237
Categoria #
all - tutte 11914
article - articoli 11412
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 82
selected - selezionate 0
volume - volumi 289
Totale 23697


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2017/201813 0000 00 01 00120
2018/2019339 00170 01 19 42759221
2019/20202644 3192316166 264144 258284 32334023376
2020/20211641 15412418347 3371 43179 193189163262
2021/20221610 43201181116 6451 82157 8646217366
2022/2023516 256332550 8264 60 0000
Totale 6951