GIORGIO, MARCO
 Distribuzione geografica
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Continente #
NA - Nord America 5.986
AS - Asia 841
EU - Europa 362
OC - Oceania 3
AF - Africa 1
SA - Sud America 1
Totale 7.194
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Nazione #
US - Stati Uniti d'America 5.984
CN - Cina 650
VN - Vietnam 172
IT - Italia 89
FI - Finlandia 88
SE - Svezia 47
DE - Germania 40
GB - Regno Unito 36
UA - Ucraina 24
IE - Irlanda 14
IN - India 12
FR - Francia 11
RU - Federazione Russa 6
NL - Olanda 5
AE - Emirati Arabi Uniti 2
CA - Canada 2
NZ - Nuova Zelanda 2
TR - Turchia 2
AT - Austria 1
AU - Australia 1
BR - Brasile 1
DK - Danimarca 1
EG - Egitto 1
JO - Giordania 1
JP - Giappone 1
SG - Singapore 1
Totale 7.194
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Città #
Fairfield 1.445
Woodbridge 671
Ashburn 578
Houston 518
Cambridge 501
Seattle 491
Wilmington 373
Ann Arbor 247
Chandler 188
Dong Ket 172
Beijing 165
Princeton 153
Medford 133
San Diego 131
Des Moines 108
Nanjing 94
Jacksonville 69
Helsinki 65
Jinan 58
Roxbury 55
Shenyang 44
Padova 30
Boardman 29
Hebei 25
Nanchang 25
Ningbo 24
Hefei 20
Zhengzhou 20
Changsha 17
Guangzhou 17
Dublin 14
Dearborn 12
Lanzhou 12
London 12
Tianjin 11
Kharkiv 10
Pune 10
Haikou 9
Jiaxing 9
Taiyuan 9
Milan 7
Redwood City 7
Shanghai 7
Sommacampagna 7
Borås 6
Fuzhou 6
Hangzhou 6
Kilburn 6
Norwalk 6
Kunming 5
Rome 5
Selvazzano Dentro 5
Lappeenranta 4
Parma 4
Chiswick 3
Ogden 3
Revere 3
Urbino 3
Chengdu 2
Chicago 2
Chongqing 2
Dubai 2
Hounslow 2
Indiana 2
Istanbul 2
Munich 2
New Bedfont 2
Paris 2
Shaoxing 2
Southwark 2
Taizhou 2
Washington 2
Xian 2
Amman 1
Bengaluru 1
Bergamo 1
Brooklyn 1
Castegnero 1
Castel Maggiore 1
Chiaravalle 1
Council Bluffs 1
Dongguan 1
Geislingen an der Steige 1
Giza 1
Jinhua 1
Kazan 1
Las Vegas 1
Latina 1
Maykop 1
Milton Keynes 1
Minatomirai 1
Monmouth Junction 1
Mykolayiv 1
Nanning 1
Orange 1
Paese 1
Pavia 1
Pinehaven 1
Prescot 1
Qingdao 1
Totale 6.724
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Nome #
Diabetes-associated myelopoiesis drives stem cell mobilopathy through an OSM-p66Shc signaling pathway 155
1. Novel neuroferritinopathy mouse model (ftl 498instc) shows progressive brain iron dysregulation, morphological signs of early neurodegeneration and motor coordination deficits 154
p66Shc deletion or deficiency protects from obesity but not metabolic dysfunction in mice and humans 134
Diabetes causes bone marrow autonomic neuropathy and impairs stem cell mobilization via dysregulated p66Shc and Sirt1 119
The cellular prion protein counteracts cardiac oxidative stress 117
Electron transfer between cytochrome c and p66Shc generates reactive oxygen species that trigger mitochondrial apoptosis 112
The p66(Shc) redox adaptor protein is induced by saturated fatty acids and mediates lipotoxicity-induced apoptosis in pancreatic beta cells. 112
New aspects of p66Shc in ischaemia reperfusion injury and other cardiovascular diseases 107
The p66ShcA adaptor protein regulates healing after myocardial infarction 105
Ablation of the gene encoding p66(Shc) protects mice against AGE-induced glomerulopathy by preventing oxidant-dependent tissue injury and further AGE accumulation 103
p66(Shc)-generated Oxidative Signal Promotes Fat Accumulation 102
The p53-p66Shc apoptotic pathway is dispensable for tumor suppression whereas the p66Shc-generated oxidative stress initiates tumorigenesis. 101
The Redox Enzyme p66Shc Contributes to Diabetes and Ischemia-Induced Delay in Cutaneous Wound Healing 100
Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66 Shc transcription and vascular oxidative stress in obesity 95
Sustained hippocampal neurogenesis in females is amplified in P66(Shc-/-) mice: An animal model of healthy aging 93
A p53-p66Shc signalling pathway controls intracellular redox status, levels of oxidation-damaged DNA and oxidative stress-induced apoptosis 93
Apoptosis and aging: Role of p66(Shc) Redox protein 84
Medullary thyroid carcinomas in transgenic mice expressing a polyoma carboxyl-terminal truncated middle-T and wild type small-T antigens 84
Angiogenesis inhibition by the maleimide-based small molecule GNX-686 82
Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors 82
Blood orange juice inhibits fat accumulation in mice 82
Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66(Shc) 81
Circulating Cytochrome c as Potential Biomarker of Impaired Reperfusion in ST-Segment Elevation Acute Myocardial Infarction 81
Mitochondrial redox signalling by p66Shc mediates ALS-like disease through Rac1 inactivation 81
Deletion of p66(Shc) longevity gene protects against experimental diabetic glomerulopathy by preventing diabetes-induced oxidative stress 81
Null Mutations at the p66 and Bradykinin 2 Receptor Loci Induce Divergent Phenotypes in the Diabetic Kidney 81
Mitochondrial pathways for ROS formation and myocardial injury: the relevance of p66(Shc) and monoamine oxidase 80
Gene rearrangements in the molecular pathogenesis of acute promyelocytic leukemia 79
Electrochemical study of hydrogen peroxide formation in isolated mitochondria 79
The cardioprotective effects elicited by p66(Shc) ablation demonstrate the crucial role of mitochondrial ROS formation in ischemia/reperfusion injury 78
The Shc locus regulates insulin signaling and adiposity in mammals 78
Alternative Forms and Functions of the c-kit Receptor and Its Ligand During Spermatogenesis 78
p66Shc Deletion Confers Vascular Protection in Advanced Atherosclerosis in Hypercholesterolemic Apolipoprotein E Knockout Mice 78
Greater resistance to inflammation at adulthood could contribute to extended life span of p66(Shc-/-) mice 78
Deletion of the life span determinant p66(Shc) prevents age-dependent increases in emotionality and pain sensitivity in mice 77
The life span determinant p66Shc localizes to mitochondria where it associates with mitochondrial heat shock protein 70 and regulates trans-membrane potential 77
Therapeutic synergy between tigecycline and venetoclax in a preclinical model of MYC/BCL2 double-hit B cell lymphoma 76
Moro orange juice prevents fatty liver in mice 76
p66(ShcA) modulates tissue response to hindlimb ischemia 75
Deletion of the p66(Shc) longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet 75
Decreased Superoxide Production in Macrophages of Long-lived p66Shc Knock-out Mice 74
Deletion of the lifespan determinant p66(Shc) improves performance in a spatial memory task, decreases levels of oxidative stress markers in the hippocampus and increases levels of the neurotrophin BDNF in adult mice 74
Genetic inactivation of the p66 isoform of ShcA is neuroprotective in a murine model of multiple sclerosis 74
Hydrogen peroxide: a metabolic by-product or a common mediator of ageing signals? 74
Microdrawing and highlighting a reactive surface 70
Regulatory effects of the mitochondrial energetic status on mitochondrial p66(Shc) 69
Mitochondrial DNA copy number is regulated by cellular proliferation: A role for Ras and p66 (Shc) 68
Mitochondria and vascular pathology 67
Hematopoietic and Nonhematopoietic p66Shc Differentially Regulates Stem Cell Traffic and Vascular Response to Ischemia in Diabetes 67
Electrochemical Detection of H2O2 Formation in Isolated Mitochondria. 64
Cyclophilin D counteracts P53-mediated growth arrest and promotes Ras tumorigenesis. 59
Cyanidin-3-O-β-glucoside and protocatechuic acid activate AMPK/mTOR/S6K pathway and improve glucose homeostasis in mice 59
Phosphorylation of p66Shc Downregulates PMCA4a and Sensitizes T Cells to Ca2+ Deregulation, Mitochondrial Dysfunction and Apoptosis 58
Modelling the p53/p66Shc aging pathway in the shortest living vertebrate Nothobranchius Furzeri 57
The Influence of Shc Proteins on Life Span in Mice 55
Oxidative stress and the unfulfilled promises of antioxidant agents 55
P66SHC deletion improves fertility and progeric phenotype of late-generation TERC-deficient mice but not their short lifespan 54
New aspects of p66Shc in ischemia reperfusion injury and cardiovascular diseases 54
SATURATION MUTAGENESIS OF THE HUMAN INTERLEUKIN-6 RECEPTOR-BINDING SITE - IMPLICATIONS FOR ITS 3-DIMENSIONAL STRUCTURE 53
Scanning electro-chemical microscopy reveals cancer cell redox state 51
Glucose and Lactate Miniaturized Biosensors for SECM-Based High-Spatial Resolution Analysis: A Comparative Study 51
The p66Shc knocked out mice are short lived under natural condition 50
Isolation stress affects tumor progression through a BDNF-neuroendocrine axis in a mouse model of breast cancer 49
Novel insights into the PKCβ-dependent regulation of the oxidoreductase p66Shc 49
p66(shc) and oxidative stress induced by post-ischemic reperfusion injury 48
The Determining Role of Mitochondrial Reactive Oxygen Species Generation and Monoamine Oxidase Activity in Doxorubicin-Induced Cardiotoxicity 47
Genetic ablation of p66(Shc) rescues functional and morphological abnormalities in collagen VI dystrophic mice 46
Inhibition of the Histone Demethylase LSD1 Combined with Caloric Restriction or IGF1/Insulin Inhibition Leads to Durable Responses in a Preclinical Model of Acute Myeloid Leukemia 45
On the epigenetic role of guanosine oxidation 44
In S. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase 44
THE OXIDATIVE STRESS RESPONSE GENE P66 SHC AND THE TUMOR SUPPRESSOR GENE P53 INDUCE MITOCHONDRIAL DNA DAMAGES 43
Ras-dependent carbon metabolism and transformation in mouse broblasts 42
The P66Shc/Mitochondrial Permeability Transition Pore Pathway Determines Neurodegeneration 42
Low oxygen tension maintains multipotency, whereas normoxia increases differentiation of mouse bone marrow stromal cells 42
Epigenomic profiling of archived FFPE tissues by enhanced PAT-ChIP (EPAT-ChIP) technology 42
Maternal care determinant of longevity? 42
Oxidative stress activates a specific p53 transcriptional response that regulates cellular senescence and aging 41
null 41
Inhibition of monoamine oxidases reduces doxorubicin-induced cardiomyocyte death 40
DEVELOPMENT OF PROGRESSIVE KIDNEY DAMAGE AND MYELOMA KIDNEY IN INTERLEUKIN-6 TRANSGENIC MICE 40
Cardiac Stem Cells and the Diabetic Cardiomyopathy 39
Mouse models and Longevity 39
Dietary cyanidin 3-glucoside from purple corn ameliorates doxorubicin-induced cardiotoxicity in mice 39
The mitochondrial translation machinery as a therapeutic target in Myc-driven lymphomas 38
Diabetes promotes cardiac stem cell aging and heart failure, which are prevented by deletion of the p66(shc) gene 38
Insights into the beneficial effect of caloric/ dietary restriction for a healthy and prolonged life 37
Deletion of p66Shc in mice increases the frequency of size-change mutations in the lacZ transgene 37
The Other Face of ROS: a Driver of Stem Cell Expansion in Colorectal Cancer. 37
Deletion of the redox enzyme p66shc promotes diabetic wound healing in mice 36
P66(Shc), redox signaling and aging 35
A PROMOTER WITHIN AN INTRON OF THE MOUSE C-KIT RECEPTOR GENE, DRIVES THE TRANSCRIPTION OF A TRUNCATED FORM OF THE RECEPTOR IN LATE SPERMIOGENESIS 35
P66ShcA adaptor protein facilitates heart rupture via activation of MMP-2 in an in vivo model of myocardial infarction in mice 34
Crucial role of p66ShcA in tissue damage induced by hindlimb ischaemia 34
Metabolic Constrains Rule Metastasis Progression 33
A Role for PML in Innate Immunity 31
RECOGNITION EFFICIENCY OF THE HEPATITIS-B VIRUS POLYADENYLATION SIGNALS IS TISSUE SPECIFIC IN TRANSGENIC MICE 31
Comparative analysis of histone h3k4me3 distribution in mouse liver in different diets reveals the epigenetic efficacy of cyanidin-3-o-glucoside dietary intake 30
6. PROBING OXYGEN METABOLISM IN TUMOUR AND NORMAL LIVING CELLS BY SCANNING ELECTROCHEMICAL MICROSCOPY. 29
The p66(shc) adaptor protein controls oxidative stress response and life span in mammals 28
Ablation of the p66(Shc) longevity gene provides protection towards experimental diabetic glomerulopathy in mice 28
Totale 6.537
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Categoria #
all - tutte 27.784
article - articoli 26.703
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 138
selected - selezionate 0
volume - volumi 664
Totale 55.289
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019307 0 0 0 0 0 0 0 0 0 27 59 221
2019/20202.644 319 231 6 166 264 144 258 284 323 340 233 76
2020/20211.641 154 124 183 47 33 71 43 179 193 189 163 262
2021/20221.605 43 201 181 116 64 51 82 157 86 42 217 365
2022/2023634 254 33 25 50 82 63 5 27 47 9 28 11
2023/2024289 6 28 30 36 21 47 55 39 14 13 0 0
Totale 7.353