Distribuzione geografica
Continente #
NA - Nord America 7.892
EU - Europa 1.259
AS - Asia 657
OC - Oceania 6
Continente sconosciuto - Info sul continente non disponibili 5
SA - Sud America 5
Totale 9.824
Nazione #
US - Stati Uniti d'America 7.877
CN - Cina 447
DE - Germania 356
FI - Finlandia 251
IT - Italia 241
UA - Ucraina 168
SE - Svezia 108
SG - Singapore 82
GB - Regno Unito 77
VN - Vietnam 68
IE - Irlanda 25
IN - India 21
PK - Pakistan 18
CA - Canada 15
KR - Corea 14
FR - Francia 10
NL - Olanda 9
AU - Australia 5
EU - Europa 5
AR - Argentina 4
RU - Federazione Russa 4
BG - Bulgaria 3
IR - Iran 2
AT - Austria 1
BR - Brasile 1
CH - Svizzera 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
HK - Hong Kong 1
IL - Israele 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
PH - Filippine 1
RO - Romania 1
SK - Slovacchia (Repubblica Slovacca) 1
TR - Turchia 1
TW - Taiwan 1
Totale 9.824
Città #
Fairfield 1.018
Woodbridge 844
Jacksonville 810
Ann Arbor 675
Chandler 639
Houston 622
Ashburn 519
Wilmington 442
Seattle 379
Cambridge 337
Princeton 275
Beijing 111
Des Moines 102
San Diego 99
Nanjing 98
Helsinki 95
Padova 88
Medford 86
Boardman 76
Roxbury 70
Dong Ket 68
Singapore 47
Guangzhou 43
Nanchang 33
Shenyang 31
Norwalk 29
Redwood City 28
Jiaxing 25
New York 25
Hebei 23
Changsha 21
Nürnberg 21
Dublin 20
Karachi 18
Tianjin 18
Indiana 12
Seoul 11
Washington 11
Munich 10
Venice 10
Vicenza 10
London 9
Montréal 9
Verona 9
Falls Church 8
Milan 8
Kharkiv 7
Rome 7
Tappahannock 7
Chicago 6
Detroit 6
Jinan 5
Kilburn 5
Rockville 5
Amsterdam 4
Edinburgh 4
Federal 4
Los Angeles 4
Ogden 4
Parma 4
San Francisco 4
Zhengzhou 4
Aprilia 3
Fontanelle 3
Giustino 3
Groningen 3
Haikou 3
Lanzhou 3
Lappeenranta 3
Martellago 3
Phoenix 3
Portici 3
Redmond 3
Sofia 3
Acton 2
Borås 2
Buffalo 2
Cagliari 2
Camisano 2
Cava de' Tirreni 2
Centro 2
Cherasco 2
Chiswick 2
Cleveland 2
Costa Mesa 2
Hefei 2
Hounslow 2
Islington 2
Kunming 2
Lincoln 2
Lonato 2
Marghera 2
Mcallen 2
Melbourne 2
Mestrino 2
Napoli 2
Ningbo 2
Orange 2
Paris 2
Perugia 2
Totale 8.110
Nome #
α-Synuclein Controls Mitochondrial Calcium Homeostasis by Enhancing Endoplasmic Reticulum-Mitochondria Interactions. 199
In vitro evaluation of TAT-OP1 osteogenic properties and prospects for in vivo applications. 179
Aggregation/fibrillogenesis of recombinant human prion protein and Gerstmann-Straussler-Scheinker disease peptides in the presence of metal ions. 153
Protein disulfide isomerase and glutathione are alternative substrates in the one Cys catalytic cycle of glutathione peroxidase 7 144
Human Doppel and prion protein share common membrane microdomains and internalization pathways 125
Selective and efficient immunoprecipitation of the disease-associated form of the prion protein can be mediated by nonspecific interactions between monoclonal antibodies and scrapie-associated fibrils 118
In vitro assessment of TAT - Ciliary Neurotrophic Factor therapeutic potential for peripheral nerve regeneration 118
Copper II binding to the human doppel protein may mark its functional diversity from the prion protein 116
The intracellular delivery of TAT-aequorin reveals calcium-mediated sensing of environmental and symbiotic signals by the arbuscular mycorrhizal fungus Gigaspora margarita 116
Structural and mutational analyses of protein-protein interactions between transthyretin and retinol-binding protein 115
The Parkinson's Disease-Related Protein DJ-1 Protects Dopaminergic Neurons in vivo and Cultured Cells from Alpha-Synuclein and 6-Hydroxydopamine Toxicity 114
Enhanced parkin levels favor ER-mitochondria crosstalk and guarantee Ca(2+) transfer to sustain cell bioenergetics. 114
A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein 113
Bovine prion protein as a modulator of protein kinase CK2 112
Effects of in vivo applications of peripheral blood-derived mesenchymal stromal cells (PB-MSCs) and platlet-rich plasma (PRP) on experimentally injured deep digital flexor tendons of sheep. 110
Crystal structure and refolding properties of the mutant F99S/M153T/V163A of the Green Fluorescent Protein 104
Superiority of PLK-2 as α-synuclein phosphorylating agent relies on unique specificity determinants. 104
The metabolism and imaging in live cells of the bovine prion protein in its native form or carrying single amino acid substitutions 103
Caratterizzazione di peptidi ACE-inibitori prodotti ad opera di batteri proteolitici impiegati per la realizzazione di latte-fermentati. 99
The prion protein and its paralogue Doppel affect calcium signaling in Chinese hamster ovary cells 97
Comparison in vivo applications between peripheral blood-derived mesenchymal stromal cells (PB-MSCs) and platlet-rich plasma (PRP) in injured tendons of sheep 96
Cloning and expression of human ciliary neurotrophic factor 95
TAT-mediated aequorin transduction: an alternative approach for effective calcium measurements in plant cells 94
Tools to discriminate between targets of CK2 vs PLK2/PLK3 acidophilic kinases. 93
Ciliary neurotrophic factor infused intracerebroventricularly shows reduced catabolic effects when linked to the TAT protein transduction domain. 92
A Novel Prion Protein-Tyrosine Hydroxylase Interaction 92
Recombinant human TAT-OP1 to enhance NGF neurogenic potential: preliminary studies on PC12 cells 89
An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein 86
Production and characterization of recombinant rat brain-derived neurotrophic factor and neurotrophin-3 from insect cells 85
Modulation of the structural integrity of helix F in apomyoglobin by single amino acid replacements 83
Identifying novel thrombin interactions: alpha-synuclein binds to thrombin exosites and inhibits thrombin-mediated platelet aggregation 82
Protein misfolding in Alzheimer's and Parkinson's disease: genetics and molecular mechanisms 82
Recombinant human ciliary neurotrophic factor alters the threshold of hippocampal pyramidal neuron sensitivity to excitotoxin damage: synergistic effects of monosialogangliosides. 81
The use of reverse-phase high-performance liquid chromatography and precolumn derivatization with dansyl chloride for quantitation of specific amino acids in collagen and elastin 81
In Vivo Applications of Mesenchymal Stem Cells and Platelet-Rich Plasma to Improve Tendon Regeneration in Sheep. 80
Hydrogel-based delivery of Tat-fused protein Hsp70 protects dopaminergic cells in vitro and in a mouse model of Parkinson’s disease 80
Nerve growth factor antibodies recognize neurotrophin-3 79
DJ-1 modulates a-synuclein aggregation state in a cellular model of oxidative stress: Relevance for Parkinson’s disease and involvement of HSP-70. 79
Ciliary neurotrophic factor-induced gene expression in human neuroblastoma cell lines 79
The effect of the osmolyte trimethylamine N-oxide on the stability of the prion protein at low pH 79
CNTF up-regulation of TIMP-2 in neuroblastoma cells 78
Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway. 77
Synthesis and purification of biologically active rat brain derived neurotrophic factor from Escherichia coli 75
Production, characterization and cytotoxic properties of a diphtheria toxin-ciliary neurotrophic factor fusion protein. 75
Establishment and characterization of a CHO cell line producing a secreted form of human ciliary neurotrophic factor: neuroprotective effects of the recombinant protein 74
Susceptibility of the prion protein to enzymatic phosphorylation 73
Temperature-dependent functional expression of a plant K+ channel in mammalian cells 73
Role of Lipid Rafts and GM1 in the Segregation and Processing of Prion Protein 73
Expression study on D123 gene product: evidence for high positivity in testis 72
Nerve growth factor (NGF) receptors in a central nervous system glial cell line: upregulation by NGF and brain-derived neurotrophic factor 70
Ganglioside GM1 cooperates with brain derived neurotrophic factor to protect dopaminergic neurons from 6-hydroxydopamine-induced degeneration 70
A comparative assessment of the effectiveness of adult stem cell (MSCS) and platenet rich plasma (PRP) applied on tendon lesions: preliminary results. 70
Apoptosis of spinal interneurons induced by sciatic nerve axotomy in the neonatal rat is counteracted by nerve growth factor and ciliary neurotrophic factor 70
Tat-MyoD fused proteins, together with C2c12 conditioned medium, are able to induce equine adult mesenchimal stem cells towards the myogenic fate 70
Synthesis, cytotoxic properties and effects on early and late gene induction of a chimeric diphtheria toxin-leukemia-inhibitory factor protein 69
The Small Heat Shock Protein HspB8: Role in Nervous System Physiology and Pathology 69
Rational Design of Allosteric and Selective Inhibitors of the Molecular Chaperone TRAP1 69
Ciliary neurotrophic factor fused to a protein transduction domain retains full neuroprotective activity in the absence of cytokine-like side effects. 67
Type IV collagenolytic activity linkage with the metastatic phenotype induced by ras transfection. 67
The Parkinson disease related protein DJ-1 counteracts mitochondrial impairment induced by the tumor suppressor protein p53 by enhancing Endoplasmic Reticulum-mitochondria tethering. 67
The fact of a polyoma early promoter plasmid in transgenic mice. 65
Biochemical immunohistochemical and immuno-electron microscopic characterization of monoclonal antibodies recognizing species-specific prion protein 65
Vectors for expression of ngf in eukaryotic cells. 65
Advantages and limitations of a supernegative GFP in facilitating MyoD intracellular tracking 65
Production and characterization of monoclonal antibodies to human ciliary neurotrophic factor with defined epitope recognition 64
Structure-function studies of human ciliary neurotrophic factor 63
Sonic Hedgehog (Shh) induces proliferation of neural progenitor cells isolated from rat postnatal cerebellum 61
Production and characterization of recombinant rat brain-derived neurotrophic factor and neurotrophin-3 from insect cells 61
Effects of systemic administration of ciliary neurotrophic factor on Bax and Bcl-2 proteins in the lumbar spinal cord of neonatal rats after sciatic nerve transection 59
Controlled Drug Delivery Microspheres for Osteogenic Differentiation 59
Expression of Prion proten and Doppel affects Ca2+ signalling 58
A comparative analysis of the cell properties of Dpl and PrPc 58
Synthesis and refolding of human TIMP-2 from E.coli, with specific activity for MMP-2. 58
Doppel and PrPC co-immunoprecipitate in detergent-resistant membrane domains of epithelial FRT cells 58
Transient expression of type IV collagenolytic metalloproteinase by human mononuclear phagocytes 58
In vivo application of autologous Mesenchymal stem cells (MSC) and Platelet rich plasma (PRP) in collagenase I experimental lesion. Clinical oucomes at one and four months. 55
Tyrosine and serine phosphorylation of alpha-synuclein have opposing effects on neurotoxicity and soluble oligomer formation. 55
The complete mature bovine prion protein highly expressed in Escherichia coli: biochemical and structural studies 55
Novel Interactions of Thrombin 55
Intracellular delivery of Neuroglobin using HIV-1 TAT protein transduction domain fails to protect against oxygen and glucose deprivation 55
DJ-1 is a multifunctional protein: its possible role in the control of cellular Ca2+ homeostasis. 54
The nuclear import of the transcription factor MyoD is reduced in mesenchymal stem cells grown in a 3D micro-engineered niche 54
cDNA cloning and characterization of PD1: a novel human testicular protein with different expressions in various testiculopathies 53
Hirudeco: A Hirudin Mutant Containing the Functional RGD-Loop of Decorsin 52
Ciliary Neurotrophic factor promotes survival of neonatal rat islets via the BLC-2 antiapoptotic patway 52
Sonic hedgehog (SHH) induces proliferation of neural progenitor cells isolated from rat postata cerebellum. 52
A comparative analysis of the properties of Dpl and PrPC. 52
Analysis of the effects of alpha-synuclein on mitochondrial Ca2+ homeostasis 51
The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide. 50
Identification, sequencing and mutagenesis of the gene for a D-carbamoylase from Agrobacterium radiobacter 50
ACE-inhibition and imunomodulant activity of milk fermented with lactic acid bacteria isolated from traditional Italian dairy products 50
Protective effect of TAT-delivered alpha synuclein: relevance of the C-terminal domain and involvement of HSP70 50
Structure-function studies of human ciliary neurotrophic factor. 49
Cloning of 3-hydroxyaanthranilic acid dioxygenase in E coli: charcterization of the purified enzyme and its in vitro inhibition by Zn 48
Functional expression of plant potassium channels in mammalian cells 48
Fermented milks from Enterococcus faecalis TH563 and Lactobacillus delbrueckii ssp. bulgaricus LA2 manifest different degrees of ACE-inhibitory and immunomodulatory activities 48
Organic polyanions act as complexants of prion protein in soil 48
Macromolecular organization and functional architecture of basement membranes 47
The bovine prion protein in live cells 47
Generation of a alpha-synuclein-based rat model of Parkinson's disease 47
Totale 7.782
Categoria #
all - tutte 30.771
article - articoli 23.492
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 154
patent - brevetti 907
selected - selezionate 0
volume - volumi 429
Totale 55.753

Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019180 0 0 0 0 0 0 0 0 0 0 0 180
2019/20201.900 320 38 33 136 174 163 145 220 170 247 133 121
2020/20211.562 63 126 68 181 112 148 12 167 230 112 208 135
2021/20221.613 20 249 220 87 81 93 55 167 68 27 215 331
2022/20231.494 326 127 22 154 265 211 5 92 173 18 76 25
2023/2024593 22 111 82 65 56 67 33 28 20 16 79 14
Totale 9.870