STURLESE, MATTIA
 Distribuzione geografica
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Continente #
NA - Nord America 4.211
EU - Europa 546
AS - Asia 298
SA - Sud America 9
AF - Africa 5
Totale 5.069
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Nazione #
US - Stati Uniti d'America 4.207
CN - Cina 247
IT - Italia 211
FI - Finlandia 98
DE - Germania 67
SE - Svezia 47
GB - Regno Unito 41
VN - Vietnam 23
IE - Irlanda 22
FR - Francia 20
IN - India 13
UA - Ucraina 11
ES - Italia 10
NL - Olanda 8
AR - Argentina 5
BR - Brasile 4
BE - Belgio 3
CA - Canada 3
GH - Ghana 3
PK - Pakistan 3
AT - Austria 2
HK - Hong Kong 2
IL - Israele 2
KZ - Kazakistan 2
TW - Taiwan 2
CH - Svizzera 1
CZ - Repubblica Ceca 1
DK - Danimarca 1
ET - Etiopia 1
GT - Guatemala 1
IR - Iran 1
JP - Giappone 1
KR - Corea 1
NG - Nigeria 1
RO - Romania 1
RU - Federazione Russa 1
SI - Slovenia 1
TR - Turchia 1
Totale 5.069
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Città #
Fairfield 775
Woodbridge 448
Ashburn 349
Ann Arbor 310
Chandler 306
Seattle 301
Houston 299
Cambridge 266
Wilmington 226
San Diego 98
Beijing 83
Padova 80
Helsinki 72
Princeton 65
Medford 59
Des Moines 55
Columbus 34
Boardman 28
Roxbury 27
Nanjing 26
Jacksonville 25
Dong Ket 23
Dublin 22
Ogden 16
Guangzhou 14
Falls Church 13
London 13
Jinan 10
Pune 10
Shenyang 10
Tianjin 9
Hebei 8
Nanchang 8
Cagliari 7
New York 7
Kharkiv 6
Milan 6
Santiago de Compostela 5
A Coruña 4
Changsha 4
Cordoba 4
Hounslow 4
Ningbo 4
Shanghai 4
Accra 3
Casagiove 3
Cittadella 3
Hefei 3
Jiaxing 3
Lahore 3
Leawood 3
Norwalk 3
Tappahannock 3
Treviso 3
Verona 3
Zhengzhou 3
Acton 2
Agordo 2
Alghero 2
Almaty 2
Belo Horizonte 2
Borås 2
Chicago 2
Chiswick 2
Cologno al Serio 2
Council Bluffs 2
Formia 2
Fuzhou 2
Grafing 2
Hangzhou 2
Hong Kong 2
Jerusalem 2
Kilburn 2
Kunming 2
Legnaro 2
Limena 2
Napoli 2
Negrar 2
New Bedfont 2
Orange 2
Perugia 2
Redwood City 2
Rockville 2
Schio 2
Tettnang 2
Vicenza 2
Washington 2
Aarhus 1
Alessandria 1
Americana 1
Arre 1
Arzignano 1
Beloeil 1
Berlin 1
Bhopal 1
Bisceglie 1
Bochum 1
Bolzano 1
Brentford 1
Brescia 1
Totale 4.254
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Nome #
DockBench: An Integrated Informatic Platform Bridging the Gap between the Robust Validation of Docking Protocols and Virtual Screening Simulations 168
Evaluating the effects of fluorine on biological properties and metabolic stability of some antitubulin 3-substituted 7-phenyl-pyrroloquinolinones 153
Synthesis, structure-activity relationships and biological evaluation of 7-phenyl-pyrroloquinolinone 3-amide derivatives as potent antimitotic agents 151
Deciphering the Complexity of Ligand-Protein Recognition Pathways Using Supervised Molecular Dynamics (SuMD) Simulations 139
Polyamine-based thiols in Trypanosomatids: evolution, protein structural adaptations and biological functions 133
Exploring Protein-Peptide Recognition Pathways Using a Supervised Molecular Dynamics Approach 132
1H, 13C and 15N resonance assignment of the mature form of monothiol glutaredoxin 1 from the pathogen Trypanosoma brucei 121
Targeting tubulin polymerization by novel 7-aryl-pyrroloquinolinones: Synthesis, biological activity and SARs 118
A molecular dynamics strategy for CSαβ peptides disulfide-assisted model refinement 112
AquaMMapS: an alternative tool to monitor the role of water molecules during protein-ligand association 112
Coupling Supervised Molecular Dynamics (SuMD) with Entropy Estimations To Shine Light on the Stability of Multiple Binding Sites 111
The lineage-specific, intrinsically disordered N-terminal extension of monothiol glutaredoxin 1 from trypanosomes contains a regulatory region 107
Side Chain Cyclization Based on Serine Residues: Synthesis, Structure, and Activity of a Novel Cyclic Analogue of the Parathyroid Hormone Fragment 1−11† 105
Dopamine-derived Quinones Affect the Structure of the Redox Sensor DJ-1 through Modifications at Cys-106 andCys-53 105
DockBench as docking selector tool: the lesson learned from D3R Grand Challenge 2015 104
SAR and QSAR study on 2-aminothiazole derivatives, modulators of transcriptional repression in Huntington's disease 103
MMsINC: a large-scale chemoinformatics database 101
New Trends in Inspecting GPCR-ligand Recognition Process: the Contribution of the Molecular Modeling Section (MMS) at the University of Padova 101
Targeting Protein Kinase CK1δ with Riluzole: Could It Be One of the Possible Missing Bricks to Interpret Its Effect in the Treatment of ALS from a Molecular Point of View? 100
Binding mode of AIF(370–394) peptide to CypA: insights from NMR, label-free and molecular docking studies 89
A High-Throughput Screening Identifies MICU1 Targeting Compounds 89
Can We Still Trust Docking Results? An Extension of the Applicability of DockBench on PDBbind Database 85
In silico 3D modeling of binding activities 84
The role of 5-arylalkylamino- and 5-piperazino- moieties on the 7-aminopyrazolo[4,3-d]pyrimidine core in affecting adenosine A1 and A2A receptor affinity and selectivity profiles 84
Molecular architecture and the structural basis for anion interaction in prestin and SLC26 transporters 82
Iron–Sulfur Cluster Binding by Mitochondrial Monothiol Glutaredoxin-1 ofTrypanosoma brucei: Molecular Basis of Iron–Sulfur Cluster Coordination and Relevance for Parasite Infectivity 80
1H, 13C and 15N resonance assignment of the cytosolic dithiol glutaredoxin 1 from the pathogen Trypanosoma brucei 80
Revisiting the Allosteric Regulation of Sodium Cation on the Binding of Adenosine at the Human A2A Adenosine Receptor: Insights from Supervised Molecular Dynamics (SuMD) Simulations 80
Deciphering the Molecular Recognition Mechanism of Multidrug Resistance Staphylococcus aureus NorA Efflux Pump Using a Supervised Molecular Dynamics Approach 78
FRET-Protease-Coupled Peptidyl-Prolyl cis-trans Isomerase Assay 77
The anti-apoptotic proteins DJ-1 and Mcl-1: molecular basis of different protein-ligand interactions leading to apoptosis. 77
Combining self- and cross-docking as benchmark tools: the performance of DockBench in the D3R Grand Challenge 2 76
Sulfonamido-derivatives of unsubstituted carbazoles as BACE1 inhibitors 75
The Influence of the 1-(3-Trifluoromethyl-Benzyl)-1H-Pyrazole-4-yl Moiety on the Adenosine Receptors Affinity Profile of Pyrazolo[4,3-e][1,2,4]Triazolo[1,5-c]Pyrimidine Derivatives 73
Identification of a Novel Mcl-1 Protein Binding Motif 73
Synthesis and preliminary structure-activity relationship study of 2-aryl-2H-pyrazolo[4,3-c]quinolin-3-ones as potential checkpoint kinase 1 (Chk1) inhibitors 73
NMR-Assisted Molecular Docking Methodologies 71
A Structural Model for Prestin and Related SLC26 Anion Transporters 70
Design, conformational studies and analysis of structure–function relationships of PTH (1–11) analogues: the essential role of Val in position 2 68
Synthesis, biological evaluation and molecular modeling studies of phthalazin-1(2H)-one derivatives as novel cholinesterase inhibitors 64
Synthesis and structural studies of new analogues of PTH(1-11) containing C-alpha-tetra-substituted amino acids in position 8 61
Scaffold Repurposing of in-House Chemical Library toward the Identification of New Casein Kinase 1 δinhibitors 61
The rise of molecular simulations in fragment-based drug design (FBDD): an overview 60
HT-SuMD: making molecular dynamics simulations suitable for fragment-based screening. A comparative study with NMR 58
Design, synthesis, structural analysis and biochemical studies of stapled AIF(370-394) analogues as ligand of CypA 57
A deep-learning approach toward rational molecular docking protocol selection 51
IDENTIFICATION OF NEW SARS-COV-2 MAIN PROTEASE INHIBITORS BY AN INTEGRATED IN-SILICO AND IN-VITRO STRATEGY 49
A Computational Workflow for the Identification of Novel Fragments Acting as Inhibitors of the Activity of Protein Kinase CK1 delta 49
Exploring the RNA-Recognition Mechanism Using Supervised Molecular Dynamics (SuMD) Simulations: Toward a Rational Design for Ribonucleic-Targeting Molecules? 48
MMsINC®: A New Public Large-Scale Chemoinformatics Database System 47
A new inactive conformation of SARS-CoV-2 main protease 45
New insights into key determinants for adenosine 1 receptor antagonists selectivity using supervised molecular dynamics simulations 42
Supervised Molecular Dynamics (SuMD) Insights into the mechanism of action of SARS-CoV-2 main protease inhibitor PF-07321332 42
Computationally driven discovery of SARS-CoV-2 Mpro inhibitors: from design to experimental validation 39
Novel coumarin-pyridazine hybrids as selective MAO-B inhibitors for the Parkinson’s disease therapy 38
Fungal β-glucans protect the fungal cell from plant thaumatin-like proteins and chitinase. 36
Inspecting the Mechanism of Fragment Hits Binding on SARS‐CoV‐2 M pro by Using Supervised Molecular Dynamics (SuMD) Simulations 35
Shedding Light on the Molecular Recognition of Sub-Kilodalton Macrocyclic Peptides on Thrombin by Supervised Molecular Dynamics 35
Targeting the coronavirus SARS-CoV-2: computational insights into the mechanism of action of the protease inhibitors lopinavir, ritonavir and nelfinavir 33
Targeting G protein-coupled receptors with magnetic carbon nanotubes: The A3 adenosine receptor case 32
Comparing fragment binding posesprediction using HSP90 as a key study: When bound water makes the difference 31
Comparative molecular dynamics investigation of the electromotile hearing protein prestin 25
Sodium or Not Sodium: Should Its Presence Affect the Accuracy of Pose Prediction in Docking {GPCR} Antagonists? 21
Re-Exploring the Ability of Common Docking Programs to Correctly Reproduce the Binding Modes of Non-Covalent Inhibitors of SARS-CoV-2 Protease Mpro 20
CG7630 is the Drosophila melanogaster homolog of the cytochrome c oxidase subunit COX7B 20
Supervised Molecular Dynamics (SuMD) Approaches in Drug Design 19
Ribose and Non-Ribose A2A Adenosine Receptor Agonists: Do They Share the Same Receptor Recognition Mechanism? 18
Computational Strategies to Identify New Drug Candidates against Neuroinflammation 17
From the Wuhan-Hu-1 strain to the XD and XE variants: is targeting the SARS-CoV-2 spike protein still a pharmaceutically relevant option against COVID-19? 17
Investigating RNA-protein recognition mechanisms through supervised molecular dynamics (SuMD) simulations 16
Implementing a Scoring Function Based on Interaction Fingerprint for Autogrow4: Protein Kinase CK1δ as a Case Study 15
The Multifaceted Role of GPCRs in Amyotrophic Lateral Sclerosis: A New Therapeutic Perspective? 15
Qualitative Estimation of Protein-Ligand Complex Stability through Thermal Titration Molecular Dynamics Simulations 15
A small molecule targeting the interaction between human papillomavirus E7 oncoprotein and cellular phosphatase PTPN14 exerts antitumoral activity in cervical cancer cells 14
Bat coronaviruses related to SARS-CoV-2: what about their 3CL proteases (MPro)? 13
Pyridazinones containing dithiocarbamoyl moieties as a new class of selective MAO-B inhibitors 13
Small-Molecule Inhibitor of Flaviviral NS3-NS5 Interaction with Broad-Spectrum Activity and Efficacy In Vivo 13
G-quadruplexes formation within the promoter of TEAD4 oncogene and their interaction with Vimentin 12
Thermal Titration Molecular Dynamics (TTMD): Not Your Usual Post-Docking Refinement 7
Design, synthesis and biological evaluation of novel 2,4-thiazolidinedione derivatives able to target the human BAG3 protein 6
Simultaneous detection of membrane contact dynamics and associated Ca2+ signals by reversible chemogenetic reporters 5
Fighting Antimicrobial Resistance: Insights on How the Staphylococcus aureus NorA Efflux Pump Recognizes 2-Phenylquinoline Inhibitors by Supervised Molecular Dynamics (SuMD) and Molecular Docking Simulations 4
A Novel NMR-Based Protocol to Screen Ultralow Molecular Weight Fragments 3
Thermal titration molecular dynamics (TTMD): shedding light on the stability of RNA-small molecule complexes 2
Drugging the Undruggable Trypanosoma brucei Monothiol Glutaredoxin 1 1
Totale 5.164
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Categoria #
all - tutte 20.955
article - articoli 19.657
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 465
Totale 41.077
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019358 0 0 0 0 0 0 0 0 0 69 147 142
2019/20201.004 110 54 14 76 118 64 98 118 165 84 58 45
2020/2021915 33 53 115 44 43 28 8 70 127 214 103 77
2021/20221.004 19 108 105 73 60 56 64 128 86 35 91 179
2022/2023782 123 24 16 76 147 114 8 69 110 29 52 14
2023/2024599 44 89 108 47 94 49 68 52 35 13 0 0
Totale 5.164