CASCIOFERRO, ALESSANDRO
CASCIOFERRO, ALESSANDRO
Conserved Pro-Glu (PE) and Pro-Pro-Glu (PPE) protein domains target LipY lipases of pathogenic mycobacteria to the cell surface via the ESX-5 pathway
2011 Daleke, M. H.; Cascioferro, Alessandro; de Punder, K.; Ummels, R.; Abdallah, A. M.; van der Wel, N.; Peters, P. J.; Luirink, J.; Manganelli, Riccardo; Bitter, W.
Functional dissection of the PE domain responsible for translocation of PE_PGRS33 across the mycobacterial cell wall
2011 Cascioferro, Alessandro; Daleke, M. H.; Ventura, M.; Donà, V.; Delogu, G.; Palu', Giorgio; Bitter, W.; Manganelli, Riccardo
PE is a functional domain responsible for protein translocation and localization on mycobacterial cell wall
2007 Cascioferro, Alessandro; Delogu, G; Colone, M; Sali, M; Stringaro, A; Arancia, G; Fadda, G; Palu', Giorgio; Manganelli, Riccardo
PE_PGRS30 is required for the full virulence of Mycobacterium tuberculosis
2012 Iantomasi, R.; Sali, M.; Cascioferro, Alessandro; Palucci, P.; Zumbo, A.; Soldini, S.; Rocca, S.; Greco, E.; Maulucci, G.; De Spirito, M.; Fraziano, M.; Fadda, G.; Manganelli, Riccardo; Delogu, G.
PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis
2017 Rieck, Barbara; Degiacomi, Giulia; Zimmermann, Michael; Cascioferro, Alessandro; Boldrin, Francesca; Lazar-Adler, Natalie R.; Bottrill, Andrew R.; le Chevalier, Fabien; Frigui, Wafa; Bellinzoni, Marco; Lisa, MarÃa-Natalia; Alzari, Pedro M.; Nguyen, Liem; Brosch, Roland; Sauer, Uwe; Manganelli, Riccardo; Oâ hare, Helen M.
Surface expression of MPT64 as a fusion with the PE domain of PE-PGRS33 enhances Mycobacterium bovis BCG protective activity against Mycobacterium tuberculosis in mice
2010 Sali, Michela; Di Sante, Gabriele; Cascioferro, Alessandro; Zumbo, Antonella; Nicolò, Chiara; Donà, Valentina; Rocca, Stefano; Procoli, Annabella; Morandi, Matteo; Ria, Francesco; Palu', Giorgio; Fadda, Giovanni; Manganelli, Riccardo; Delogu, Giovanni
Surface expression of MPT64 as a fusion with the PE domain of PE_PGRS33 enhances BCG protective activity against Mycobacterium tuberculosis in mice
2010 Sali, M; DI SANTE, G; Cascioferro, Alessandro; Zumbo, A; Nicolã’, C; DONÀ, V; Rocca, S; Ria, F; Palu', Giorgio; Fadda, G; Manganelli, Riccardo; Delogu, G.
Targeting Type VII/ESX Secretion Systems for Development of Novel Antimycobacterial Drugs.
2013 Bottai, D; Serafini, A; Cascioferro, Alessandro; Brosch, R; Manganelli, Riccardo
The PPE domain of PPE17 is responsible for its surface localization and can be used to express heterologous proteins on the mycobacterial surface.
2013 Donà, V; Ventura, M; Sali, M; Cascioferro, Alessandro; Provvedi, Roberta; Palu', Giorgio; Delogu, G; Manganelli, Riccardo