Algal toxicity of antibacterial agents used in intensive farming was investigated. The growth-inhibiting effects of oxytetracycline (OTC), sulphametazine (SMZ) and tylosin (TYL) were investigated by a modified test procedure based on the procedure described in the ISO 8692 (1989) protocol on the freshwater green alga Selenastrum capricornutum. Algal growth was measured as increased chlorophyll concentration. The chlorophyll was extracted with ethanol and fluorometrically determined. Results were quantified in terms of growth rates using Weibull equation to describe the concentration response relationship. The toxicity (EC50 value, mg/l) were: OTC, 4,17; SMZ, 10,7;TYL, 0,949, respectively.

Environmental risk assessment of antibacterial agents using an in vitro test

CAPOLONGO, FRANCESCA;MONTESISSA, CLARA
2001

Abstract

Algal toxicity of antibacterial agents used in intensive farming was investigated. The growth-inhibiting effects of oxytetracycline (OTC), sulphametazine (SMZ) and tylosin (TYL) were investigated by a modified test procedure based on the procedure described in the ISO 8692 (1989) protocol on the freshwater green alga Selenastrum capricornutum. Algal growth was measured as increased chlorophyll concentration. The chlorophyll was extracted with ethanol and fluorometrically determined. Results were quantified in terms of growth rates using Weibull equation to describe the concentration response relationship. The toxicity (EC50 value, mg/l) were: OTC, 4,17; SMZ, 10,7;TYL, 0,949, respectively.
2001
Atti LV Convegno Nazionale S.I.S. Vet
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/1339380
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