"Monade dominante" come "Monade attuatrice". Sostanze viventi e ontologia delle relazioni in G.W. Leibniz

What kind of relationship subsists between an “organism” and a “monas dominans »? In some texts, Leibniz claims that the soul « actuat » the organic body and in the late debate with Stahl he describes the « monas dominans » as a « monas actuatrix ». But how does the monas « actualize » the organic body ? and what implies the semantic of the word « agere » here used by Leibniz ? Is it also possibile to describe this event in terms of « whole/part » relationship ? The aim of this paper is to sketch out the status quaestionis of the topic by discussing some of the most recent studies. More specifically to propose an interpretation of the « monas dominans » as the « nota distinguens » of the whole organism.