The toxicities of sulfamethazine, sulfadimethoxine, sulfadiazine, and sulfamerazine were determined individually and in paired mixtures against Daphnia magna.Sulfamerazine (EC50 = 277 mg/L) was the least toxic and sulfamethazine (EC50 = 202 mg/L) the most toxic. Eight out of the nine mixture tested produced a statistically supported less than additive toxicity (isobologram method), posing a lower toxicological hazard to Daphnia magna than the respective individual sulfonamides. The use of solvents to produce a suitably concentrated stock solution is also discussed.
TOSSICITA' ACUTA, INDIVIDUALE E BINARIA, DI QUATTRO SULFAMIDICI DI USO VETERINARIO, SUL MICROCROSTACEO Daphnia magna.
GALLINA, GUGLIELMO;FIORETTO, BARBARA;DE LIGUORO, MARCO
2008
Abstract
The toxicities of sulfamethazine, sulfadimethoxine, sulfadiazine, and sulfamerazine were determined individually and in paired mixtures against Daphnia magna.Sulfamerazine (EC50 = 277 mg/L) was the least toxic and sulfamethazine (EC50 = 202 mg/L) the most toxic. Eight out of the nine mixture tested produced a statistically supported less than additive toxicity (isobologram method), posing a lower toxicological hazard to Daphnia magna than the respective individual sulfonamides. The use of solvents to produce a suitably concentrated stock solution is also discussed.File in questo prodotto:
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