Gold nanoparticles decorated with thermosensitive polymers reversibly switched from stable colloidal dispersion to a self-associated state by temperature changes. Above the polymer LCST, the coated nanoparticles were taken into human MCF7 cells at a higher extent compared to what was observed at 34 °C. The laser irradiation of the intracellular nanoparticle clusters induced cell damage.

Thermosensitive Decorated Gold Nanoparticles For Thermal Triggered Biological Recognition.

SALMASO, STEFANO;CALICETI, PAOLO;MASTROTTO F;AMENDOLA, VINCENZO;MENEGHETTI, MORENO;
2009

Abstract

Gold nanoparticles decorated with thermosensitive polymers reversibly switched from stable colloidal dispersion to a self-associated state by temperature changes. Above the polymer LCST, the coated nanoparticles were taken into human MCF7 cells at a higher extent compared to what was observed at 34 °C. The laser irradiation of the intracellular nanoparticle clusters induced cell damage.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11577/2464384
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