We report the preparation of a “smart” system obtained by decorating gold nanoparticles with pH responsive polymers and folic acid. The gold nanoparticle decoration is aimed at improving site-selectivity in the tumour compartment where the mild acidic conditions trigger the biorecognition of folate receptor overexpressing cancer cells.
Titolo: | Gold nanoparticles with site-triggered biorecognition for cancer targeting. |
Autori: | |
Data di pubblicazione: | 2013 |
Abstract: | We report the preparation of a “smart” system obtained by decorating gold nanoparticles with pH responsive polymers and folic acid. The gold nanoparticle decoration is aimed at improving site-selectivity in the tumour compartment where the mild acidic conditions trigger the biorecognition of folate receptor overexpressing cancer cells. |
Handle: | http://hdl.handle.net/11577/2666436 |
Appare nelle tipologie: | 04.01 - Contributo in atti di convegno |
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