In this work we have demonstrated that oxidation of the numerous methione resiues of the protein allergen Ses-i-2 by leukocyte myeloperoxidase abrogates the allergenic properties of the protein allergen.
Effect of methionine oxidation on the structure, stability and allergenic properties of the major Ses I 2 allergen from Sesamum indicum
GALLA, DANIELA;BRUN, PAOLA;CASTAGLIUOLO, IGNAZIO;ZANOTTI, GIUSEPPE;DE FILIPPIS, VINCENZO
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Abstract
In this work we have demonstrated that oxidation of the numerous methione resiues of the protein allergen Ses-i-2 by leukocyte myeloperoxidase abrogates the allergenic properties of the protein allergen.
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