Ovarian tumours are uncommon in veterinary medicine. A total of 11 dogs with abdominal effusion due to ovarian neoplasm histologically confirmed were included: papillary adenocarcinoma (8), granulosa cell tumour (2), and a mixed gonadostromal tumour (granulosa cell tumour and luteoma). In abdominal effusion of 7 cases out of 8 papillary adenocarcinomas, neoplastic cells were present. Cytology of the effusions revealed high cellularity, large tridimensional clusters of cells arranged in papillary pattern, and small aggregates of cells with microacinar arrangement. Tightly cohesive, roundish, oval or cuboidal cells with moderate anisocytosis and anisokaryosis, variable nuclear atypia, and scarce to moderate amount of sometimes vacuolated grey cytoplasm were present. Granulosa cell tumours caused serosanguineous effusion without neoplastic cells. Gonadostromal tumour caused serosanguineous effusion with neoplastic cells. Smears of the effusion were characterized by high cellularity, aggregates of moderately cohesive cells, dysmetric nuclei, prominent nucleoli and large grey, often microvacuolated cytoplasm. In conclusion, in case of ovarian papillary adenocarcinoma and carcinomatosis, abdominal effusion may contain cells deriving from ovarian neoplasm, which is different from other ovarian neoplasms which rarely cause abdominal effusion containing neoplastic cells.
RILIEVI CITOLOGICI IN 11 CASI DI VERSAMENTO PERITONEALE IN CORSO DI NEOPLASIA OVARICA NEL CANE
FERRO, SILVIA
2005
Abstract
Ovarian tumours are uncommon in veterinary medicine. A total of 11 dogs with abdominal effusion due to ovarian neoplasm histologically confirmed were included: papillary adenocarcinoma (8), granulosa cell tumour (2), and a mixed gonadostromal tumour (granulosa cell tumour and luteoma). In abdominal effusion of 7 cases out of 8 papillary adenocarcinomas, neoplastic cells were present. Cytology of the effusions revealed high cellularity, large tridimensional clusters of cells arranged in papillary pattern, and small aggregates of cells with microacinar arrangement. Tightly cohesive, roundish, oval or cuboidal cells with moderate anisocytosis and anisokaryosis, variable nuclear atypia, and scarce to moderate amount of sometimes vacuolated grey cytoplasm were present. Granulosa cell tumours caused serosanguineous effusion without neoplastic cells. Gonadostromal tumour caused serosanguineous effusion with neoplastic cells. Smears of the effusion were characterized by high cellularity, aggregates of moderately cohesive cells, dysmetric nuclei, prominent nucleoli and large grey, often microvacuolated cytoplasm. In conclusion, in case of ovarian papillary adenocarcinoma and carcinomatosis, abdominal effusion may contain cells deriving from ovarian neoplasm, which is different from other ovarian neoplasms which rarely cause abdominal effusion containing neoplastic cells.Pubblicazioni consigliate
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