Effectiveness of a diet with low advanced glycation end products, in improving glycoxidation and lipid peroxidation: a long-term investigation in patients with chronic renal failure

Advanced glycation end products (AGEs) have a crucial role in the process of atherosclerosis, particularly in patients with chronic renal failure (CRF), which have a dual form of damage, namely an increased formation of serum AGEs and their reduced clearance [1, 2]. We previously observed that AGEs can react with the peritoneal matrix protein, giving a reason for the gradual loss of peritoneal membrane function observed in patients undergoing long-term peritoneal dialysis [3, 4].