SerpinB3 is a cysteine protease inhibitor involved in several biological activities. It is progressively expressed in chronic liver disease, but not in normal liver. The role in vascular reactivity of this serpin, belonging to the same family of Angiotensin II, is still unknown. Our aim was to evaluate the in vivo and in vitro effects of SerpinB3 on systemic and splanchnic hemodynamics.

Hyperdynamic circulatory syndrome in a mouse model transgenic for SerpinB3

Villano G.;Verardo A.;Martini A.;Brocco S.;Pesce P.;Sacerdoti D.;Di Pascoli M.;Fedrigo M.;Castellani C.;Angelini A.;Pontisso P.;Bolognesi M.
2020

Abstract

SerpinB3 is a cysteine protease inhibitor involved in several biological activities. It is progressively expressed in chronic liver disease, but not in normal liver. The role in vascular reactivity of this serpin, belonging to the same family of Angiotensin II, is still unknown. Our aim was to evaluate the in vivo and in vitro effects of SerpinB3 on systemic and splanchnic hemodynamics.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11577/3314632
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