Analisi automatizzata di immagini corneali per la diagnosi precoce e lo screening su larga scala in oftalmologia

In this thesis, to automate the analysis of confocal microscopy images of the corneal sub-basal nerve plexus, new methodologies are proposed for the identification and tracing of the structures present in this corneal layer, with particular attention to nerve fibers. Starting from this tracing, the parameters of clinical interest are estimated. The latter will be useful for making diagnoses, for mass screening, and for obtaining an early diagnosis of some pathological and/or inflammatory states.