MAMMANO, FABIO
MAMMANO, FABIO
Dipartimento di Fisica e Astronomia "Galileo Galilei" - DFA
Connexin hemichannel blockade by abEC1.1 disrupts glioblastoma progression, suppresses invasiveness, and reduces hyperexcitability in preclinical models
2025 Donati, Viola; Di Pietro, Chiara; Persano, Luca; Rampazzo, Elena; Panarelli, Mariateresa; Cambria, Clara; Selimi, Anna; Manfreda, Lorenzo; De Oliveira Do Rêgo, Ana Gabriela; La Sala, Gina; Sprega, Camilla; Calistri, Arianna; Ciubotaru, Catalin Dacian; Yang, Guang; Zonta, Francesco; Antonucci, Flavia; Marazziti, Daniela; Mammano, Fabio
A fully human IgG1 antibody targeting connexin 32 extracellular domain blocks CMTX1 hemichannel dysfunction in an in vitro model
2024 Tettey-Matey, Abraham; Donati, Viola; Cimmino, Chiara; Di Pietro, Chiara; Buratto, Damiano; Panarelli, Mariateresa; Reale, Alberto; Calistri, Arianna; Fornaini, Maria Vittoria; Zhou, Ruhong; Yang, Guang; Zonta, Francesco; Marazziti, Daniela; Mammano, Fabio
Antibody gene transfer treatment drastically improves epidermal pathology in a keratitis ichthyosis deafness syndrome model using male mice
2023 Peres, C.; Sellitto, C.; Nardin, C.; Putti, S.; Orsini, T.; Di Pietro, C.; Marazziti, D.; Vitiello, A.; Calistri, A.; Rigamonti, M.; Scavizzi, F.; Raspa, M.; Zonta, F.; Yang, G.; White, T. W.; Mammano, F.
Genome-wide screening reveals the genetic basis of mammalian embryonic eye development
2023 Chee, J. M.; Lanoue, L.; Clary, D.; Higgins, K.; Bower, L.; Flenniken, A.; Guo, R.; Adams, D. J.; Bosch, F.; Braun, R. E.; Brown, S. D. M.; Chin, H. J. G.; Dickinson, M. E.; Hsu, C. W.; Dobbie, M.; Gao, X.; Galande, S.; Grobler, A.; Heaney, J. D.; Herault, Y.; de Angelis, M. H.; Mammano, F.; Nutter, L. M. J.; Parkinson, H.; Qin, C.; Shiroishi, T.; Sedlacek, R.; Seong, J. K.; Xu, Y.; Ackert-Bicknell, C.; Adams, D.; Adoum, A. T.; Aguilar-Pimentel, J. A.; Akoma, U.; Ali-Hadji, D.; Amarie, O. V.; André, P.; Auburtin, A.; Bam’Hamed, C.; Beckers, J.; Beig, J.; Berberovic, Z.; Bezginov, A.; Birling, M. C.; Boroviak, K.; Bottomley, J.; Bürger, A.; Busch, D. H.; Butterfield, N. C.; Cacheiro, P.; Calzada-Wack, J.; Cambridge, E. L.; Camilleri, S.; Champy, M. F.; Cater, H.; Charles, P.; Chesler, E. J.; Cho, Y. L.; Christiansen, A. E.; Cipriani, V.; Cockle, N.; Codner, G.; Creighton, A.; Cruz, M.; Curry, K. F.; D’Souza, A.; Danisment, O.; Delbarre, D.; Dewhurst, H. F.; Doe, B.; Dorr, A.; Giesert, F.; Duddy, G.; Duffin, K.; El Amri, A.; Elrick, H.; Eskandarian, M.; Fray, M.; Frost, A.; Fuchs, H.; Gailus-Durner, V.; Gampe, K. K.; Ganguly, M.; Gannon, D.; Garrett, L.; Gertsenstein, M.; Gleeson, D.; Goodwin, L.; Graw, J.; Grimsrud, K.; Haselimashhadi, H.; Hobson, L.; Hörlein, A.; Hölter, S. M.; Hong, S. H.; Horner, N.; Trainor, A. G.; Huang, Z.; Kane, C.; Katsman, Y.
A Quantitative Assay for Ca2+ Uptake through Normal and Pathological Hemichannels
2022 Nardin, Chiara; Tettey-Matey, Abraham; Donati, Viola; Marazziti, Daniela; Di Pietro, Chiara; Peres, Chiara; Raspa, Marcello; Zonta, Francesco; Yang, Guang; Gorelik, Maryna; Singh, Serena; Cardarelli, Lia; Sidhu, Sachdev S; Mammano, Fabio
Analysis of genome-wide knockout mouse database identifies candidate ciliopathy genes
2022 Higgins, K.; Moore, B. A.; Berberovic, Z.; Adissu, H. A.; Eskandarian, M.; Flenniken, A. M.; Shao, A.; Imai, D. M.; Clary, D.; Lanoue, L.; Newbigging, S.; Nutter, L. M. J.; Adams, D. J.; Bosch, F.; Braun, R. E.; Brown, S. D. M.; Dickinson, M. E.; Dobbie, M.; Flicek, P.; Gao, X.; Galande, S.; Grobler, A.; Heaney, J. D.; Herault, Y.; de Angelis, M. H.; Chin, H. -J. G.; Mammano, F.; Qin, C.; Shiroishi, T.; Sedlacek, R.; Seong, J. -K.; Xu, Y.; Lloyd, K. C. K.; Mckerlie, C.; Moshiri, A.
Calcium Signaling in the Photodamaged Skin: In Vivo Experiments and Mathematical Modeling
2022 Donati, Viola; Peres, Chiara; Nardin, Chiara; Scavizzi, Ferdinando; Raspa, Marcello; Ciubotaru, Catalin D; Bortolozzi, Mario; Pedersen, Morten Gram; Mammano, Fabio
Commercially derived versatile optical architecture for two-photon STED, wavelength mixing and label-free microscopy
2022 Peres, C.; Nardin, C.; Yang, G.; Mammano, F.
Connexin 30 deletion exacerbates cochlear senescence and age-related hearing loss
2022 Paciello, Fabiola; Zorzi, Veronica; Raspa, Marcello; Scavizzi, Ferdinando; Grassi, Claudio; Mammano, Fabio; Fetoni, Anna Rita
Connexin30-Deficiency Causes Mild Hearing Loss With the Reduction of Endocochlear Potential and ATP Release
2022 Chen, J.; Chen, P.; He, B.; Gong, T.; Li, Y.; Zhang, J.; Lv, J.; Mammano, F.; Hou, S.; Yang, J.
Dietary intake of deuterium oxide decreases cochlear metabolism and oxidative stress levels in a mouse model of age-related hearing loss
2022 Hou, S.; Chen, P.; He, J.; Chen, J.; Zhang, J.; Mammano, F.; Yang, J.
Extensive identification of genes involved in congenital and structural heart disorders and cardiomyopathy
2022 Spielmann, Nadine; Miller, Gregor; Oprea, Tudor I.; Hsu, Chih-Wei; Fobo, Gisela; Frishman, Goar; Montrone, Corinna; Haseli Mashhadi, Hamed; Mason, Jeremy; Munoz Fuentes, Violeta; Leuchtenberger, Stefanie; Ruepp, Andreas; Wagner, Matias; Westphal, Dominik S.; Wolf, Cordula; Görlach, Agnes; Sanz-Moreno, Adrián; Cho, Yi-Li; Teperino, Raffaele; Brandmaier, Stefan; Sharma, Sapna; Galter, Isabella Rikarda; Östereicher, Manuela A.; Zapf, Lilly; Mayer-Kuckuk, Philipp; Rozman, Jan; Teboul, Lydia; Bunton-Stasyshyn, Rosie K. A.; Cater, Heather; Stewart, Michelle; Christou, Skevoulla; Westerberg, Henrik; Willett, Amelia M.; Wotton, Janine M.; Roper, Willson B.; Christiansen, Audrey E.; Ward, Christopher S.; Heaney, Jason D.; Reynolds, Corey L.; Prochazka, Jan; Bower, Lynette; Clary, David; Selloum, Mohammed; Bou About, Ghina; Wendling, Olivia; Jacobs, Hugues; Leblanc, Sophie; Meziane, Hamid; Sorg, Tania; Audain, Enrique; Gilly, Arthur; Rayner, Nigel W.; Aguilar-Pimentel, Juan A.; Becker, Lore; Garrett, Lillian; Hölter, Sabine M.; Amarie, Oana V.; Calzada-Wack, Julia; Klein-Rodewald, Tanja; da Silva-Buttkus, Patricia; Lengger, Christoph; Stoeger, Claudia; Gerlini, Raffaele; Rathkolb, Birgit; Mayr, Daniela; Seavitt, John; Gaspero, Angelina; Green, Jennie R.; Garza, Arturo; Bohat, Ritu; Wong, Leeyean; Mcelwee, Melissa L.; Kalaga, Sowmya; Rasmussen, Tara L.; Lorenzo, Isabel; Lanza, Denise G.; Samaco, Rodney C.; Veeraragaven, Surabi; Gallegos, Juan J.; Kašpárek, Petr; Petrezsélyová, Silvia; King, Ruairidh; Johnson, Sara; Cleak, James; Szkoe-Kovacs, Zsombor; Codner, Gemma; Mackenzie, Matthew; Caulder, Adam; Kenyon, Janet; Gardiner, Wendy; Phelps, Hayley; Hancock, Rhys; Norris, Claire; Moore, Michayla A.; Seluke, Audrie M.; Urban, Rachel; Kane, Coleen; Goodwin, Leslie O.; Peterson, Kevin A.; Mckay, Matthew; Cook, Jenn J.; Lowy, Jacob P.; Mcfarland, Michael; Wood, Joshua A.; Willis, Brandon J.; Tolentino, Heather; Tolentino, Todd; Schuchbauer, Michael; Salazar, Jason; Johnson, Jennifer; Munson, Rebecca; Ayadi, Abdel; Pavlovic, Guillaume; Birling, Marie-Christine; Jacquot, Sylvie; Ali-Hadji, Dalila; Charles, Philippe; Andre, Philippe; Champy, Marie-France; Riet, Fabrice; Vukobradovic, Igor; Berberovic, Zorana; Qu, Dawei; Guo, Ruolin; D’Souza, Abigail; Huang, Ziyue; Camilleri, Susan; Ganguly, Milan; Adissu, Hibret; Eskandarian, Mohammed; Shang, Xueyuan; Duffin, Kyle; Xu, Catherine; Roberton, Kyle; Laurin, Valerie; Lan, Qing; Sleep, Gillian; Creighton, Amie; Lintott, Lauri; Gertsenstein, Marina; Pereira, Monica; Tondat, Sandra; Patel, Amit; Cruz, Maribelle; Bezginov, Alex; Miller, David; Hy, Wang; Yoshiki, Atsushi; Tanaka, Nobuhiko; Tamura, Masaru; Liu, Zhiwei; Ermakova, Olga; Ferrara, Anna; Fruscoloni, Paolo; Seisenberger, Claudia; Bürger, Antje; Giesert, Florian; Ambrose, J. C.; Arumu gam, P.; Bevers, R.; Bleda, M.; Boardman-Pretty, F.; Boustred, C. R.; Brittain, H.; Caulfield, M. J.; Chan, G. C.; Fowler, T.; Giess, A.; Hamblin, A.; Henderson, S.; Hubbard, T. J. P.; Jackson, R.; Jones, L. J.; Kasperaviciute, D.; Kayikci, M.; Kousathanas, A.; Lahnstein, L.; Leigh, S. E. A.; Leong, I. U. S.; Lopez, F. J.; Maleady-Crowe, F.; Mcentagart, M.; Minneci, F.; Moutsianas, L.; Mueller, M.; Murugaesu, N.; Need, A. C.; O‘donovan, P.; Odhams, C. A.; Patch, C.; Perez-Gil, D.; Pereira, M. B.; Pullinger, J.; Rahim, T.; Rendon, A.; Rogers, T.; Savage, K.; Sawant, K.; Scott, R. H.; Siddiq, A.; Sieghart, A.; Smith, S. C.; Sosinsky, A.; Stuckey, A.; Tanguy, M.; Taylor-Tavares, A. L.; Thomas, E. R. A.; Thompson, S. R.; Tucci, A.; Welland, M. J.; Williams, E.; Witkowska, K.; Wood, S. M.; Hitz, Marc-Phillip; Zeggini, Eleftheria; Wolf, Eckhard; Sedlacek, Radislav; Murray, Steven A.; Svenson, Karen L.; Braun, Robert E.; White, Jaqueline K.; Kelsey, Lois; Gao, Xiang; Shiroishi, Toshihiko; Xu, Ying; Seong, Je Kyung; Mammano, Fabio; Tocchini-Valentini, Glauco P.; Beaudet, Arthur L.; Meehan, Terrence F.; Parkinson, Helen; Smedley, Damian; Mallon, Ann-Marie; Wells, Sara E.; Grallert, Harald; Wurst, Wolfgang; Marschall, Susan; Fuchs, Helmut; Brown, Steve D. M.; Flenniken, Ann M.; Nutter, Lauryl M. J.; Mckerlie, Colin; Herault, Yann; Lloyd, K. C. Kent; Dickinson, Mary E.; Gailus-Durner, Valerie; Hrabe de Angelis, Martin
Failure Of Hearing Acquisition in Mice With Reduced Expression of Connexin 26 Correlates With the Abnormal Phasing of Apoptosis Relative to Autophagy and Defective ATP-Dependent Ca2+ Signaling in Kölliker’s Organ
2022 Sun, Lianhua; Gao, Dekun; Chen, Junmin; Hou, Shule; Li, Yue; Huang, Yuyu; Mammano, Fabio; Chen, Jianyong; Yang, Jun
Connexin hemichannel activation by s-nitrosoglutathione synergizes strongly with photodynamic therapy potentiating anti-tumor bystander killing
2021 Nardin, C.; Peres, C.; Putti, S.; Orsini, T.; Colussi, C.; Mazzarda, F.; Raspa, M.; Scavizzi, F.; Salvatore, A. M.; Chiani, F.; Tettey-Matey, A.; Kuang, Y.; Yang, G.; Retamal, M. A.; Mammano, F.
CXCR2 increases in ALS cortical neurons and its inhibition prevents motor neuron degeneration in vitro and improves neuromuscular function in SOD1G93A mice
2021 La Cognata, V.; Golini, E.; Iemmolo, R.; Balletta, S.; Morello, G.; De Rosa, C.; Villari, A.; Marinelli, S.; Vacca, V.; Bonaventura, G.; Dell'Albani, P.; Aronica, E.; Mammano, F.; Mandillo, S.; Cavallaro, S.
Harnessing the Therapeutic Potential of Antibodies Targeting Connexin Hemichannels
2021 Buratto, Damiano; Donati, Viola; Zonta, Francesco; Mammano, Fabio
miRNA and mRNA Profiling Links Connexin Deficiency to Deafness via Early Oxidative Damage in the Mouse Stria Vascularis
2021 Gentile, G.; Paciello, F.; Zorzi, V.; Spampinato, A. G.; Guarnaccia, M.; Crispino, G.; Tettey-Matey, A.; Scavizzi, F.; Raspa, M.; Fetoni, A. R.; Cavallaro, S.; Mammano, F.
Single-Cell RNA Sequencing Analysis Reveals Greater Epithelial Ridge Cells Degeneration During Postnatal Development of Cochlea in Rats
2021 Chen, J.; Gao, D.; Chen, J.; Hou, S.; He, B.; Li, Y.; Li, S.; Zhang, F.; Sun, X.; Mammano, F.; Sun, L.; Yang, J.; Zheng, G.
A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant mice
2020 Kuang, Y.; Zorzi, V.; Buratto, D.; Ziraldo, G.; Mazzarda, F.; Peres, C.; Nardin, C.; Salvatore, A. M.; Chiani, F.; Scavizzi, F.; Raspa, M.; Qiang, M.; Chu, Y.; Shi, X.; Li, Y.; Liu, L.; Shi, Y.; Zonta, F.; Yang, G.; Lerner, R. A.; Mammano, F.
Distinct expression patterns of apoptosis and autophagy-Associated proteins and genes during postnatal development of spiral ganglion neurons in rat
2020 Hou, S.; Chen, P.; Chen, J.; Chen, J.; Sun, L.; Chen, J.; He, B.; Li, Y.; Qin, H.; Hong, Y.; Li, S.; He, J.; Gao, D.; Mammano, F.; Yang, J.