ROMANO, ORIANA
ROMANO, ORIANA
Dipartimento di Medicina Molecolare - DMM
Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression
2022 Antoniou, P.; Hardouin, G.; Martinucci, P.; Frati, G.; Felix, T.; Chalumeau, A.; Fontana, L.; Martin, J.; Masson, C.; Brusson, M.; Maule, G.; Rosello, M.; Giovannangeli, C.; Abramowski, V.; de Villartay, J. -P.; Concordet, J. -P.; Del Bene, F.; El Nemer, W.; Amendola, M.; Cavazzana, M.; Cereseto, A.; Romano, O.; Miccio, A.
Computational methods for the integrative analysis of single-cell data
2021 Forcato, M.; Romano, O.; Bicciato, S.
Concise Review: Epigenetic Regulation of Hematopoiesis: Biological Insights and Therapeutic Applications
2017 Antoniani, C.; Romano, O.; Miccio, A.
Dynamic Transcriptional and Epigenetic Regulation of Human Epidermal Keratinocyte Differentiation
2016 Cavazza, A.; Miccio, A.; Romano, O.; Petiti, L.; Malagoli Tagliazucchi, G.; Peano, C.; Severgnini, M.; Rizzi, E.; De Bellis, G.; Bicciato, S.; Mavilio, F.
Epigenomic landscape of human colorectal cancer unveils an aberrant core of pan-cancer enhancers orchestrated by YAP/TAZ
2021 Della Chiara, G.; Gervasoni, F.; Fakiola, M.; Godano, C.; D'Oria, C.; Azzolin, L.; Bonnal, R. J. P.; Moreni, G.; Drufuca, L.; Rossetti, G.; Ranzani, V.; Bason, R.; De Simone, M.; Panariello, F.; Ferrari, I.; Fabbris, T.; Zanconato, F.; Forcato, M.; Romano, O.; Caroli, J.; Gruarin, P.; Sarnicola, M. L.; Cordenonsi, M.; Bardelli, A.; Zucchini, N.; Ceretti, A. P.; Mariani, N. M.; Cassingena, A.; Sartore-Bianchi, A.; Testa, G.; Gianotti, L.; Opocher, E.; Pisati, F.; Tripodo, C.; Macino, G.; Siena, S.; Bicciato, S.; Piccolo, S.; Pagani, M.
Exome sequencing and bioinformatic approaches reveals rare sequence variants involved in cell signalling and elastic fibre homeostasis: new evidence in the development of ectopic calcification
2019 Boraldi, F.; Lofaro, F. D.; Romano, O.; Grilli, A.; Losi, L.; Moscarelli, P.; Bicciato, S.; Quaglino, D.
GATA factor transcriptional activity: Insights from genome-wide binding profiles
2020 Romano, O.; Miccio, A.
GATA Factor-Mediated Gene Regulation in Human Erythropoiesis
2020 Romano, O.; Petiti, L.; Felix, T.; Meneghini, V.; Portafax, M.; Antoniani, C.; Amendola, M.; Bicciato, S.; Peano, C.; Miccio, A.
High-throughput transcriptome analyses from ASPIRO, a phase 1/2/3 study of gene replacement therapy for X-linked myotubular myopathy
2023 Andreoletti, G.; Romano, O.; Chou, H. -J.; Sefid-Dashti, M. J.; Grilli, A.; Chen, C.; Lakshman, N.; Purushothaman, P.; Varfaj, F.; Mavilio, F.; Bicciato, S.; Urbinati, F.
Induction of fetal hemoglobin synthesis by CRISPR/Cas9-mediated editing of the human b-globin locus
2018 Antoniani, C.; Meneghini, V.; Lattanzi, A.; Felix, T.; Romano, O.; Magrin, E.; Weber, L.; Pavani, G.; Hoss, S. E.; Kurita, R.; Nakamura, Y.; Cradick, T. J.; Lundberg, A. S.; Porteus, M.; Amendola, M.; Nemer, W. E.; Cavazzana, M.; Mavilio, F.; Miccio, A.
Mutated clones driving leukemic transformation are already detectable at the single-cell level in CD34-positive cells in the chronic phase of primary myelofibrosis
2021 Parenti, S.; Rontauroli, S.; Carretta, C.; Mallia, S.; Genovese, E.; Chiereghin, C.; Peano, C.; Tavernari, L.; Bianchi, E.; Fantini, S.; Sartini, S.; Romano, O.; Bicciato, S.; Tagliafico, E.; Della Porta, M.; Manfredini, R.
Novel lentiviral vectors for gene therapy of sickle cell disease combining gene addition and gene silencing strategies
2023 Brusson, Mégane; Chalumeau, Anne; Martinucci, Pierre; Romano, Oriana; Felix, Tristan; Poletti, Valentina; Scaramuzza, Samantha; Ramadier, Sophie; Masson, Cecile; Ferrari, Giuliana; Mavilio, Fulvio; Cavazzana, Marina; Amendola, Mario; Miccio, Annarita
Plerixafor enables safe, rapid, efficient mobilization of hematopoietic stem cells in sickle cell disease patients after exchange transfusion
2018 Lagresle-Peyrou, C.; Lefrere, F.; Magrin, E.; Ribeil, J. -A.; Romano, O.; Weber, L.; Magnani, A.; Sadek, H.; Plantier, C.; Gabrion, A.; Ternaux, B.; Felix, T.; Couzin, C.; Stanislas, A.; Treluyer, J. -M.; Lamhaut, L.; Joseph, L.; Delville, M.; Miccio, A.; Andre-Schmutz, I.; Cavazzana, M.
popsicleR: A R Package for Pre-processing and Quality Control Analysis of Single Cell RNA-seq Data
2022 Grandi, F.; Caroli, J.; Romano, O.; Marchionni, M.; Forcato, M.; Bicciato, S.
Regeneration of the entire human epidermis using transgenic stem cells
2017 Hirsch, T.; Rothoeft, T.; Teig, N.; Bauer, J. W.; Pellegrini, G.; De Rosa, L.; Scaglione, D.; Reichelt, J.; Klausegger, A.; Kneisz, D.; Romano, O.; Seconetti, A. S.; Contin, R.; Enzo, E.; Jurman, I.; Carulli, S.; Jacobsen, F.; Luecke, T.; Lehnhardt, M.; Fischer, M.; Kueckelhaus, M.; Quaglino, D.; Morgante, M.; Bicciato, S.; Bondanza, S.; De Luca, M.
Retroviral scanning: Mapping MLV integration sites to define cell-specific regulatory regions
2017 Romano, O.; Cifola, I.; Poletti, V.; Severgnini, M.; Peano, C.; de Bellis, G.; Mavilio, F.; Miccio, A.
Single-cell analyses reveal YAP/TAZ as regulators of stemness and cell plasticity in glioblastoma
2021 Castellan, M.; Guarnieri, A.; Fujimura, A.; Zanconato, F.; Battilana, G.; Panciera, T.; Sladitschek, H. L.; Contessotto, P.; Citron, A.; Grilli, A.; Romano, O.; Bicciato, S.; Fassan, M.; Porcu, E.; Rosato, A.; Cordenonsi, M.; Piccolo, S.
TIM4 expression by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responses
2021 Caronni, N.; Piperno, G. M.; Simoncello, F.; Romano, O.; Vodret, S.; Yanagihashi, Y.; Dress, R.; Dutertre, C. -A.; Bugatti, M.; Bourdeley, P.; Del Prete, A.; Schioppa, T.; Mazza, E. M. C.; Collavin, L.; Zacchigna, S.; Ostuni, R.; Guermonprez, P.; Vermi, W.; Ginhoux, F.; Bicciato, S.; Nagata, S.; Benvenuti, F.
Transcriptional, epigenetic and retroviral signatures identify regulatory regions involved in hematopoietic lineage commitment
2016 Romano, O.; Peano, C.; Tagliazucchi, G. M.; Petiti, L.; Poletti, V.; Cocchiarella, F.; Rizzi, E.; Severgnini, M.; Cavazza, A.; Rossi, C.; Pagliaro, P.; Ambrosi, A.; Ferrari, G.; Bicciato, S.; De Bellis, G.; Mavilio, F.; Miccio, A.