| Nome |
# |
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Pharmacological aspects of ANGPTL3 and ANGPTL4 inhibitors: new therapeutic approaches for the treatment of atherogenic dyslipidemia, file e14fb26c-04d2-3de1-e053-1705fe0ac030
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871
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A selective alpha1D-adrenoreceptor antagonist inhibits human prostate cancer cell proliferation and motility "in vitro", file e14fb268-107a-3de1-e053-1705fe0ac030
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394
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|
Plasma PCSK9 levels and lipoprotein distribution are preserved in carriers of genetic HDL disorders, file e14fb26a-e2e8-3de1-e053-1705fe0ac030
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249
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|
PCSK9 antagonists and inflammation, file e14fb269-fff5-3de1-e053-1705fe0ac030
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229
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|
PCSK9 induces a pro-inflammatory response in macrophages, file e14fb26a-6269-3de1-e053-1705fe0ac030
|
140
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|
High Density Lipoproteins Inhibit Oxidative Stress-Induced Prostate Cancer Cell Proliferation, file e14fb26a-6bb7-3de1-e053-1705fe0ac030
|
140
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|
Suppressor of Cytokine Signaling-3 (SOCS-3) induces Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) expression in hepatic HepG2 cell line, file e14fb268-21fc-3de1-e053-1705fe0ac030
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133
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Circulating Levels of Proprotein Convertase Subtilisin/Kexin Type 9 and Arterial Stiffness in a Large Population Sample: Data From the Brisighella Heart Study, file e14fb26a-59e8-3de1-e053-1705fe0ac030
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125
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Angiopoietin-Like 3 (ANGPTL3) and Atherosclerosis: Lipid and Non-Lipid Related Effects, file e14fb26a-e939-3de1-e053-1705fe0ac030
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122
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Himalayan Nettle Girardinia diversifolia as a Candidate Ingredient for Pharmaceutical and Nutraceutical Applications-Phytochemical Analysis and In Vitro Bioassays, file e14fb26c-8522-3de1-e053-1705fe0ac030
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119
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The small heat shock protein B8 (HSPB8) modulates proliferation and migration of breast cancer cells, file e14fb26a-5d09-3de1-e053-1705fe0ac030
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111
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Proprotein Convertase Subtilisin/Kexin Type 9, Brain Cholesterol Homeostasis and Potential Implication for Alzheimer's Disease, file e14fb26b-f482-3de1-e053-1705fe0ac030
|
110
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Effect of a novel nutraceutical combination on serum lipoprotein functional profile and circulating PCSK9, file e14fb26a-5a9f-3de1-e053-1705fe0ac030
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106
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Exploring the anticancer potential of diiron bis-cyclopentadienyl complexes with bridging hydrocarbyl ligands: Behavior in aqueous media and in vitro cytotoxicity, file e14fb26e-75a0-3de1-e053-1705fe0ac030
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91
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Clinical Pharmacology of Statins: an Update, file e14fb26d-3cdb-3de1-e053-1705fe0ac030
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87
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Naturally Occurring PCSK9 Inhibitors, file e14fb26c-ec44-3de1-e053-1705fe0ac030
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80
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Drug-Drug Interactions of Direct Oral Anticoagulants (DOACs): From Pharmacological to Clinical Practice, file 55a89ffd-d793-4ca8-98ba-40f399ea8ffc
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64
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New sulfurated derivatives of cinnamic acids and rosmaricine as inhibitors of STAT3 and NF-kappa B transcription factors, file e14fb26a-0530-3de1-e053-1705fe0ac030
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62
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Clinical approach to the inflammatory etiology of cardiovascular diseases, file e14fb26d-38c3-3de1-e053-1705fe0ac030
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62
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Proprotein convertase subtilisin/kexin type 9: an update on the cardiovascular outcome studies, file e14fb26d-21d7-3de1-e053-1705fe0ac030
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59
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Mitochondrial depletion of glutaredoxin 2 induces metabolic dysfunction associated fatty liver disease in mice., file e14fb270-4cbe-3de1-e053-1705fe0ac030
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58
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Pharmacological rationale for the very early treatment of acute coronary syndrome with monoclonal antibodies anti-PCSK9, file 0ec758a6-fd77-4267-a0d5-277070fdec21
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52
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Serum Levels of PCSK9 Are Increased in Patients With Active Ulcerative Colitis Representing a Potential Biomarker of Disease Activity: A Cross-sectional Study, file f915e990-e003-4d8d-82b4-b11f9b3f9d6e
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49
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Mechanism of bempedoic acid induced cholelithiasis: A role for statins to limit this adverse effect?, file 59d776c3-3579-45a9-a592-c0ef62a7790b
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40
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Lipoprotein(a) and PCSK9 inhibition: clinical evidence, file e14fb26d-5d23-3de1-e053-1705fe0ac030
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29
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Observational study on the benefit of a nutritional supplement, supporting immune function and energy metabolism, on chronic fatigue associated with the SARS-CoV-2 post-infection progress, file e14fb26f-0df8-3de1-e053-1705fe0ac030
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27
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Lomitapide does not alter PCSK9 and Lp(a) levels in homozygous familial hypercholesterolemia patients: analysis on cytokines and lipid profile, file e14fb26e-f23e-3de1-e053-1705fe0ac030
|
25
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Bergamot (Citrus bergamia) peel extract as new hypocholesterolemic agent modulating PCSK9 expression, file 08681585-c455-4cd9-8732-07854fa5d926
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21
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Development of a novel, fully human, anti-PCSK9 antibody with potent hypolipidemic activity by utilizing phage display-based strategy, file e14fb26e-9af8-3de1-e053-1705fe0ac030
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21
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Proprotein convertase subtilisin kexin type 9 and high-density lipoprotein metabolism: experimental animal models and clinical evidence, file e14fb268-0028-3de1-e053-1705fe0ac030
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20
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A Nutraceutical Formulation Containing Brown Algae Reduces Hepatic Lipid Accumulation by Modulating Lipid Metabolism and Inflammation in Experimental Models of NAFLD and NASH, file b3a4c8e2-98ba-475d-aabc-481c84fc970c
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16
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Investigating the in vitro mode of action of okra (Abelmoschus esculentus) as hypocholesterolemic, anti-inflammatory, and antioxidant food, file fbe1bf59-a17f-4ca8-a959-cd438705e72e
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15
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Cytotoxic performances of new anionic cyclometalated Pt(II) complexes bearing chelated O^O ligands, file e14fb26c-35ad-3de1-e053-1705fe0ac030
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14
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Cholesterol-Lowering Action of a Novel Nutraceutical Combination in Uremic Rats: Insights into the Molecular Mechanism in a Hepatoma Cell Line, file e14fb26c-6971-3de1-e053-1705fe0ac030
|
14
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Side effects of statins-from pathophysiology and epidemiology to diagnostic and therapeutic implications, file e14fb26f-b59f-3de1-e053-1705fe0ac030
|
14
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REL-1017 (Esmethadone) Increases Circulating BDNF Levels in Healthy Subjects of a Phase 1 Clinical Study, file e14fb26e-fea0-3de1-e053-1705fe0ac030
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13
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PCSK9 Levels Are Raised in Chronic HCV Patients with Hepatocellular Carcinoma, file e14fb26d-85af-3de1-e053-1705fe0ac030
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12
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Lipid Lowering Drugs: Present Status and Future Developments, file e14fb26e-5dc5-3de1-e053-1705fe0ac030
|
12
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The Modulation of PCSK9 and LDLR by Supercritical CO2 Extracts of Mentha longifolia and Isolated Piperitone Oxide, an In Vitro Study, file e14fb26f-11be-3de1-e053-1705fe0ac030
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12
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Impact of nutraceuticals on markers of systemic inflammation: Potential relevance to cardiovascular diseases – A position paper from the International Lipid Expert Panel (ILEP), file e14fb26f-2149-3de1-e053-1705fe0ac030
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12
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Fixed Combination for the Treatment of Dyslipidaemia, file 914e7870-e769-4e80-841d-645af00bf681
|
11
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Depression and cardiovascular risk-association among Beck Depression Inventory, PCSK9 levels and insulin resistance, file e14fb26d-5ddb-3de1-e053-1705fe0ac030
|
11
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Proprotein Convertase Subtilisin/Kexin Type 9: A View beyond the Canonical Cholesterol-Lowering Impact, file e14fb26f-1f69-3de1-e053-1705fe0ac030
|
10
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Legacy perfluoro-alkyl substances impair LDL-cholesterol uptake independently from PCSK9-function, file 3b15a467-0a55-4dbe-bfb6-882aeaae369c
|
9
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Relationship between circulating PCSK9 and markers of subclinical atherosclerosis—the improve study, file e14fb26e-ba22-3de1-e053-1705fe0ac030
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9
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New players in the treatment of hypercholesterolaemia: focus on bempedoic acid and inclisiran, file e14fb26f-1849-3de1-e053-1705fe0ac030
|
9
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Proteolysis Targeting Chimeric Molecules: Tuning Molecular Strategies for a Clinically Sound Listening, file 638b5f9c-d199-4c1b-a5d6-d439743f9b86
|
8
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Pcsk9 induces rat smooth muscle cell proliferation and counteracts the pleiotropic effects of simvastatin, file e14fb26e-7f35-3de1-e053-1705fe0ac030
|
7
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Unmet Clinical Needs in Elderly Patients Receiving Direct Oral Anticoagulants for Stroke Prevention in Non-valvular Atrial Fibrillation, file e14fb26f-184b-3de1-e053-1705fe0ac030
|
7
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Impact of soy β-conglycinin peptides on PCSK9 protein expression in HepG2 cells, file e14fb26f-960e-3de1-e053-1705fe0ac030
|
7
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NMR, LC-MS Characterization of Rydingia michauxii Extracts, Identification of Natural Products Acting as Modulators of LDLR and PCSK9, file e14fb270-4211-3de1-e053-1705fe0ac030
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7
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Phage display for targeting PCSK9, file e14fb26e-c72f-3de1-e053-1705fe0ac030
|
6
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From lipoprotein apheresis to proprotein convertase subtilisin/kexin type 9 inhibitors: Impact on low-density lipoprotein cholesterol and C-reactive protein levels in cardiovascular disease patients, file e14fb26a-fa94-3de1-e053-1705fe0ac030
|
5
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Sex-specific predictors of PCSK9 levels in a European population: The IMPROVE Study, file e14fb26d-14f7-3de1-e053-1705fe0ac030
|
5
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PCSK9 Affects Astrocyte Cholesterol Metabolism and Reduces Neuron Cholesterol Supplying In Vitro: Potential Implications in Alzheimer's Disease, file 1c23a99e-4a51-47e9-93e6-042081dc5769
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4
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HDL Cholesterol Efflux and Serum Cholesterol Loading Capacity Alterations Associate to Macrophage Cholesterol Accumulation in FH Patients with Achilles Tendon Xanthoma, file 844d9c52-d99e-4967-be4a-1f7b093ffcd8
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4
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Efficacy and Safety of Mipomersen: A Systematic Review and Meta-Analysis of Randomized Clinical Trials, file e14fb26b-c363-3de1-e053-1705fe0ac030
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4
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PCSK9 Involvement in Aortic Valve Calcification, file e14fb26b-c9d4-3de1-e053-1705fe0ac030
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4
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LEPTIN, RESISTIN, AND PCSK9 - THE ROLE OF STAT3, file e14fb26c-f18d-3de1-e053-1705fe0ac030
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4
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PCSK9 ablation attenuates Aβ pathology, neuroinflammation and cognitive dysfunctions in 5XFAD mice, file e5fc367f-d1fc-497f-9d91-fc091c4360ef
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4
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PCSK9 as a Positive Modulator of Platelet Activation, file e14fb26f-43b7-3de1-e053-1705fe0ac030
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3
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Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits, file 4350b16c-a0bc-4f13-a763-56b8166d3163
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2
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In Vitro and In Vivo Sucrosomial® Berberine Activity on Insulin Resistance, file 8cf834d0-1a2f-4bef-b9bd-def1ed1bc4d2
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2
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Effects of Handroanthus impetiginosus (Mart. ex DC.) Mattos extract on inflammatory, immune, atherogenic profile and differentiation in THP-1 cell line, file b0642b05-d5c2-4519-afe7-3ffc99ef2506
|
2
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Left main coronary wall thickness correlates with the carotid intima media thickness and may provide a new marker of cardiovascular risk, file e14fb26b-398a-3de1-e053-1705fe0ac030
|
2
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Long-term exposure to air pollution raises circulating levels of proprotein convertase subtilisin/kexin type 9 in obese individuals, file e14fb26b-43dd-3de1-e053-1705fe0ac030
|
2
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PCSK9 Confers Inflammatory Properties to Extracellular Vesicles Released by Vascular Smooth Muscle Cells, file f6f0d75f-e03c-4325-ae54-a5427bc005cc
|
2
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Nutrition Intervention and Cardiovascular Disease, file d0d04b74-68f8-4975-856c-8d933fda5d89
|
1
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Geranylgeraniol prevents the simvastatin-induced PCSK9 expression: role of the small G protein Rac1, file e14fb269-c4e0-3de1-e053-1705fe0ac030
|
1
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Bococizumab for the treatment of hypercholesterolaemia, file e14fb269-c8c5-3de1-e053-1705fe0ac030
|
1
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Peptide modulators of Rac1/Tiam1 protein-protein interaction: An alternative approach for cardiovascular diseases, file e14fb26a-36dd-3de1-e053-1705fe0ac030
|
1
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PRESENT THERAPEUTIC ROLE OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS, file e14fb26a-5cad-3de1-e053-1705fe0ac030
|
1
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Effects of polysaccharides from Inonotus obliquus and its chromium (III) complex on advanced glycation end-products formation, α-amylase, α-glucosidase activity and H2O2-induced oxidative damage in hepatic L02 cells, file e14fb26a-da4f-3de1-e053-1705fe0ac030
|
1
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Changes in circulating pro-protein convertase subtilisin/kexin type 9 levels – experimental and clinical approaches with lipid-lowering agents, file e14fb26b-0fdb-3de1-e053-1705fe0ac030
|
1
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Differential effects of red yeast rice, Berberis aristata and Morus alba extracts on PCSK9 and LDL uptake, file e14fb26b-8b78-3de1-e053-1705fe0ac030
|
1
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Identification of Ellagitannins in the Unripe Fruit of Rubus Chingii Hu and Evaluation of its Potential Antidiabetic Activity, file e14fb26b-bc10-3de1-e053-1705fe0ac030
|
1
|
|
Monofunctional PtII Complexes Based on 8-Aminoquinoline: Synthesis and Pharmacological Characterization, file e14fb26c-0aa6-3de1-e053-1705fe0ac030
|
1
|
|
Edoxaban and the Issue of Drug-Drug Interactions: From Pharmacology to Clinical Practice, file e14fb26c-fbb0-3de1-e053-1705fe0ac030
|
1
|
| Totale |
3.991 |