A model is proposed to describe the early thyroxine distribution in man. The four main compartments, plasma, liver, interstitial fluids and other tissues, are characterized by their transfer rate constants and by their distribution spaces. The model implementation on a digital computer only requires easily obtainable data; clinical investigations are simplified by the simulation technique. © 1972 International Federation for Medical and Biological Engineering.
A functional model of early thyroxine distribution in man
BENETAZZO, LUIGINO;BUSNARDO, BENEDETTO;CLEMENTE, GIORGIO
1972
Abstract
A model is proposed to describe the early thyroxine distribution in man. The four main compartments, plasma, liver, interstitial fluids and other tissues, are characterized by their transfer rate constants and by their distribution spaces. The model implementation on a digital computer only requires easily obtainable data; clinical investigations are simplified by the simulation technique. © 1972 International Federation for Medical and Biological Engineering.
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