The cooperativity of the torsional displacements in the conformational transitions of oligomeric chains has been analyzed theoretically in terms of a master equation for the configurational jumps derived from a multidimensional diffusion equation. A prototype model constructed as a linear array of rotors interacting according to a bistable potential has been used to obtain simple analytical expressions for the transition frequencies in the limit of an infinite chain. The problem of the gauche-trans conformational processes in phospholipid chains has been faced by a Monte Carlo approach applied to the evaluation of the kinetic rates for the transitions occurring at each specific segment of the chain.

Conformational process and cooperativity effects in chain molecules

FERRARINI, ALBERTA;MORO, GIORGIO;NORDIO, PIER LUIGI;POLIMENO, ANTONINO
1988

Abstract

The cooperativity of the torsional displacements in the conformational transitions of oligomeric chains has been analyzed theoretically in terms of a master equation for the configurational jumps derived from a multidimensional diffusion equation. A prototype model constructed as a linear array of rotors interacting according to a bistable potential has been used to obtain simple analytical expressions for the transition frequencies in the limit of an infinite chain. The problem of the gauche-trans conformational processes in phospholipid chains has been faced by a Monte Carlo approach applied to the evaluation of the kinetic rates for the transitions occurring at each specific segment of the chain.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11577/123277
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