Effect of aging on endothelium-dependent and independent relaxation was studied in rabbit aorta. Response to Ach was similar in young and adult animals. ATP and NaNO2 showed both lower potency and efficacy in adult animals. Vascular smooth muscle might be of relevance in the age-related impaired relaxation to ATP. © 1991, Taylor & Francis Group, LLC. All rights reserved.
AGE-RELATED IMPAIRMENT OF RELAXATION TO ATP IN RABBIT AORTAS
RAGAZZI, EUGENIO;CAPARROTTA, LAURA;
1991
Abstract
Effect of aging on endothelium-dependent and independent relaxation was studied in rabbit aorta. Response to Ach was similar in young and adult animals. ATP and NaNO2 showed both lower potency and efficacy in adult animals. Vascular smooth muscle might be of relevance in the age-related impaired relaxation to ATP. © 1991, Taylor & Francis Group, LLC. All rights reserved.
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