Hensen's cells in the isolated cochlea were stimulated by extracellular adenosine 5 ' -triphosphate (XTP) applied to their endolymphatic surface while changes in membrane current and intracellular calcium concentration ([Ca(2+)](i)) were measured simultaneously. The response consisted of (i) an initial rapid inward current accompanied by elevation of the [Ca(2+)](i), (ii) a more slowly rising inward current accompanied by a rise of the [Ca(2+)](i) and (iii) a slowly developing reduction of input conductance.
Purinergic control of intercellular communication between Hensen's cells of the guinea pig cochlea
MAMMANO, FABIO
2001
Abstract
Hensen's cells in the isolated cochlea were stimulated by extracellular adenosine 5 ' -triphosphate (XTP) applied to their endolymphatic surface while changes in membrane current and intracellular calcium concentration ([Ca(2+)](i)) were measured simultaneously. The response consisted of (i) an initial rapid inward current accompanied by elevation of the [Ca(2+)](i), (ii) a more slowly rising inward current accompanied by a rise of the [Ca(2+)](i) and (iii) a slowly developing reduction of input conductance.File in questo prodotto:
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