Dilithiated norephedrine and ephedrine have been utilised in the enantioselective rearrangement of cyclic epoxides to allylic alcohols, with dilithiated norephedrine generally giving the best enantioselectivity. Dilithiated ephedrine offered better levels of substrate conversion, but with lower enantioselectivity.

Epoxide rearrangements using dilithiated aminoalcohols as chiral bases

SPOLAORE, BARBARA
2002

Abstract

Dilithiated norephedrine and ephedrine have been utilised in the enantioselective rearrangement of cyclic epoxides to allylic alcohols, with dilithiated norephedrine generally giving the best enantioselectivity. Dilithiated ephedrine offered better levels of substrate conversion, but with lower enantioselectivity.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11577/1369385
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