We review our recent work on adenosine receptors, a family of GPCRs; focusing our attention on A3 adenosine receptor, we have demonstrated that the reciprocal integration of different theoretical and experimental disciplines can be very useful for the successful protein-based design of new, potent and selective receptor ligands.
Demystifying the three dimensional structure of G protein- coupled receptors (GPCRs) with the aid of molecular modeling
MORO, STEFANO;DEFLORIAN, FRANCESCA;
2003
Abstract
We review our recent work on adenosine receptors, a family of GPCRs; focusing our attention on A3 adenosine receptor, we have demonstrated that the reciprocal integration of different theoretical and experimental disciplines can be very useful for the successful protein-based design of new, potent and selective receptor ligands.File in questo prodotto:
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