A relatively large BACE1 inhibitor containing a hydroxyethylamine aspartyl protease inhibitor motif was identified by high-throughput screening, and has inspired the design of new “lighter”, biologically active derivatives, representing a promising new class anti-Alzheimer's drugs.

alpha-Naphthylaminopropan-2-ol Derivatives as BACE1 Inhibitors

BORTOLATO, ANDREA;MORO, STEFANO;
2008

Abstract

A relatively large BACE1 inhibitor containing a hydroxyethylamine aspartyl protease inhibitor motif was identified by high-throughput screening, and has inspired the design of new “lighter”, biologically active derivatives, representing a promising new class anti-Alzheimer's drugs.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/2267838
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