Among the numerous chemical methods reported in literature and currently used to synthesize magnetic nanoparticles for medical imaging applications the following can be found: microemulsion technology, sol-gel syntheses, sonochemical reactions, hydrothermal reactions, hydrolysis and thermolysis of iron complex precursors, flow injection syntheses and electrospray syntheses (Laurent, 2008). The synthesis of superparamagnetic nanoparticles is a complex process because of their colloidal nature. The first main chemical challenge consists of defining experimental conditions, leading to a monodisperse population of magnetic grains of suitable size. The second critical point is to select a reproducible process that can be industrialized without any complex purification procedure, such as ultracentrifugation, size-exclusion chromatography, magnetic filtration, or flow field gradient. A novel procedure to synthesize homogeneous maghemite based (γ-Fe2O3) superparamagnetic iron oxide nanoparticles is proposed.

Maghemite nanoparticles and method for preparing thereof

MAGRO, MASSIMILIANO;VALLE, GIORGIO;VIANELLO, FABIO
2012

Abstract

Among the numerous chemical methods reported in literature and currently used to synthesize magnetic nanoparticles for medical imaging applications the following can be found: microemulsion technology, sol-gel syntheses, sonochemical reactions, hydrothermal reactions, hydrolysis and thermolysis of iron complex precursors, flow injection syntheses and electrospray syntheses (Laurent, 2008). The synthesis of superparamagnetic nanoparticles is a complex process because of their colloidal nature. The first main chemical challenge consists of defining experimental conditions, leading to a monodisperse population of magnetic grains of suitable size. The second critical point is to select a reproducible process that can be industrialized without any complex purification procedure, such as ultracentrifugation, size-exclusion chromatography, magnetic filtration, or flow field gradient. A novel procedure to synthesize homogeneous maghemite based (γ-Fe2O3) superparamagnetic iron oxide nanoparticles is proposed.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/2418280
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