Among the numerous chemical methods reported in literature and currently used to synthesize magnetic nanoparticles for medical imaging applications the following can be found: microemulsion technology, sol-gel syntheses, sonochemical reactions, hydrothermal reactions, hydrolysis and thermolysis of iron complex precursors, flow injection syntheses and electrospray syntheses (Laurent, 2008). The synthesis of superparamagnetic nanoparticles is a complex process because of their colloidal nature. The first main chemical challenge consists of defining experimental conditions, leading to a monodisperse population of magnetic grains of suitable size. The second critical point is to select a reproducible process that can be industrialized without any complex purification procedure, such as ultracentrifugation, size-exclusion chromatography, magnetic filtration, or flow field gradient. A novel procedure to synthesize homogeneous maghemite based (γ-Fe2O3) superparamagnetic iron oxide nanoparticles is proposed.
Titolo: | Maghemite nanoparticles and method for preparing thereof | |
Autori: | ||
Data di pubblicazione: | 2012 | |
Abstract: | Among the numerous chemical methods reported in literature and currently used to synthesize magnetic nanoparticles for medical imaging applications the following can be found: microemulsion technology, sol-gel syntheses, sonochemical reactions, hydrothermal reactions, hydrolysis and thermolysis of iron complex precursors, flow injection syntheses and electrospray syntheses (Laurent, 2008). The synthesis of superparamagnetic nanoparticles is a complex process because of their colloidal nature. The first main chemical challenge consists of defining experimental conditions, leading to a monodisperse population of magnetic grains of suitable size. The second critical point is to select a reproducible process that can be industrialized without any complex purification procedure, such as ultracentrifugation, size-exclusion chromatography, magnetic filtration, or flow field gradient. A novel procedure to synthesize homogeneous maghemite based (γ-Fe2O3) superparamagnetic iron oxide nanoparticles is proposed. | |
Handle: | http://hdl.handle.net/11577/2418280 | |
Appare nelle tipologie: | 05.01 - Brevetto |