A rapid and efficient microwave-assisted protocol is described that greatly improves a recent synthetic method developed for quinazoline synthesis. The synthetic protocol is based on the use of cycles of microwave irradiation. The optimization process is reported and the experimental results are compared with those of the conventional synthetic route.
A microwave improvement in the synthesis of the quinazoline scaffold
CHILIN, ADRIANA;MARZARO, GIOVANNI;ZANATTA, SAMUELE;GUIOTTO, ADRIANO
2007
Abstract
A rapid and efficient microwave-assisted protocol is described that greatly improves a recent synthetic method developed for quinazoline synthesis. The synthetic protocol is based on the use of cycles of microwave irradiation. The optimization process is reported and the experimental results are compared with those of the conventional synthetic route.
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