A new synthetic pathway to quinazolines is described. This new method uses hexamethylenetetramine in TFA and potassium ferricyanide in aqueous ethanolic KOH, starting from simple N-protected anilines. The method affords substituted quinazolines with high selectivities and good yields, reducing reaction-time and work-up operations.
A new access to quinazolines from simple anilines
CHILIN, ADRIANA;MARZARO, GIOVANNI;ZANATTA, SAMUELE;BARBIERI, VERA;MANZINI, PAOLO;GUIOTTO, ADRIANO
2006
Abstract
A new synthetic pathway to quinazolines is described. This new method uses hexamethylenetetramine in TFA and potassium ferricyanide in aqueous ethanolic KOH, starting from simple N-protected anilines. The method affords substituted quinazolines with high selectivities and good yields, reducing reaction-time and work-up operations.
File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
Tetrahedron_2006_MANZINI.pdf
Accesso riservato
Tipologia:
Published (Publisher's Version of Record)
Licenza:
Accesso privato - non pubblico
Dimensione
254.78 kB
Formato
Adobe PDF
|
254.78 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
