Chloro and acetato complexes of platinum(II) with functionalized thioethers

The chloro complexes [PtCl2(RSR')(2)] (1-10) (RSR' = MeSCH2C(O)OMe, 1; MeSCH2C(O)OEt, 2; MeSCH2C(O)Omenthyl(-), 3: MeSCH2CH2C(O)OMe, 4; S(CH2)(3)CHC(O)OEt, 5; EtSCH2C(O)Me; 6; MeSCH C(O)Me, 7; MeSPh, 8; MeS-o-C6H4Me, 9; and MeS-o-C6H4Et, 10) are obtained in high yield (63-90%) by reaction of [PtCl2(PhCN)(2)] with the proper thioether in 1/2 molar ratio. in anhydrous chloroform. at reflux under argon for ca. 10 h. The X-ray crystal structure of [PtCl2(MeS-o-C6H4Me)(2)] (9) shows an almost regular trans square planar geometry (triclinic, space group P (1) over bar, a 6.806(1), b 7.789(2), c 10.085(3) Angstrom, alpha 101.80(2)degrees, beta 69.55(2)degrees, gamma 115.27(2)degrees, R(F-o) 0.023, R-w(F-o(2)) 0.065). The dichloro complexes react with silver acetate in a complex manner, which depends on the nature of the thioether, and only with RSR' = MeSPh the simple diacetato complex [Pt(OAc)(2)(RSR')(2)] is obtained as the major product.