Ten new C21-steroidal derivatives, namely gordonosides A–L (1–10) were isolated from a chloroform extract of the aerial parts of Hoodia gordonii, a plant widely used in the nutraceutical market as an ingredient of weight loss supplements. Compounds (2–10) are based on 3,14-dihydroxy-pregn-5-en-17-one aglycone (1). Their structures were characterized on the basis of HR-MS spectrometry and both 1D and 2D NMR techniques
Steroidal glycosides from Hoodia gordonii
DALL'ACQUA, STEFANO;INNOCENTI, GABBRIELLA
2007
Abstract
Ten new C21-steroidal derivatives, namely gordonosides A–L (1–10) were isolated from a chloroform extract of the aerial parts of Hoodia gordonii, a plant widely used in the nutraceutical market as an ingredient of weight loss supplements. Compounds (2–10) are based on 3,14-dihydroxy-pregn-5-en-17-one aglycone (1). Their structures were characterized on the basis of HR-MS spectrometry and both 1D and 2D NMR techniques
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