These data raise the attractive possibility that mGlu2/3 receptor ligands (either low doses of agonists or antagonists) may be used as adjunctive drugs to shorten the latency of antidepressant medication, provided that these drugs will also show a good profile of safety and tolerability, as can be predicted from animal studies.
Group-II metabotropic glutamate receptor ligands as adjunctive drugs in the treatment of depression: a new strategy to shorten the latency of antidepressant medication?
ZUSSO, MORENA;GIUSTI, PIETRO;
2007
Abstract
These data raise the attractive possibility that mGlu2/3 receptor ligands (either low doses of agonists or antagonists) may be used as adjunctive drugs to shorten the latency of antidepressant medication, provided that these drugs will also show a good profile of safety and tolerability, as can be predicted from animal studies.
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