Pancreas Preservation With Celsior Solution in a Pig Autotransplantation Model: Comparative Study With University of Wisconsin Solution

Celsior solution (CS) is a relatively new extracellular type of solution that was initially proposed as a cardioplegic solution in heart transplantation. Because of its low viscosity and antioxidant and antiedema properties, it was subsequently investigated experimentally and found suitable for lung, kidney, liver, and pancreas preservation. It is now used with increasing frequency in clinical transplantation settings. However, as far as pancreatic preservation is concerned, this solution has never been compared with other solutions used in organ perfusion and preservation. The aim of this study was to compare CS with University of Wisconsin solution (UWS), the pancreas preserving solution routinely used in clinical transplantation, in an experimental pancreas transplantation model.