An overview is given of a useful fluorescence probe for DNA detection. Its emission properties are drastically switched by a change of the base composition within the binding pocket because of a delicate balance between emission and redox properties. Thus, this compound constitutes a useful platform for a new generation of selective DNA-sensing probes.
6-aminoacridizinium bromide: a fluorescence probe which lights up in AT-rich regions of DNA
VIOLA G.;VEDALDI, DANIELA ESTER
2003
Abstract
An overview is given of a useful fluorescence probe for DNA detection. Its emission properties are drastically switched by a change of the base composition within the binding pocket because of a delicate balance between emission and redox properties. Thus, this compound constitutes a useful platform for a new generation of selective DNA-sensing probes.
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