Uveal lymphoid infiltration: clinical, angiographic and cytological aspects.

Purpose: To report the clinical, angiographic and cytological features of uveal lymphoid infiltration diagnosed by orbital fine needle aspiration biopsy of orbital nodules. Methods: Three patients (2 males, 1 female) affected by suspected uveal lymphoid infiltration and simultaneous orbital nodules underwent fine needle aspiration biopsy of orbital lesions. Flu- orescein and indocyanine green (ICG) angiography were .also performed before and after therapy. Results: Cytological specimens from orbital masses documented B lymphocytes and plasmacytoid cells in all cases. ICG angiography demonstrated the infiltration of choroi- dal lobules. Uveal and orbital infiltrates slowly disappeared after radiotherapy. ICG angiog- raphy documented the resolution of neoplastic choroidal infiltration. Conclusions: Uveal lymphoid infiltration is a rare clinical condition difficult to diagnose. Fine needle aspiration biopsy of simultaneous orbital nodules may give enough material to confirm clinical diagno- sis. CR: None