The mechanisms involved in aldosterone overproduction and adrenal cell proliferation of FH-II remain unknown. The genetic basis of this disorder may involve heritable alterations of more than one gene and/or reflect an unrestrained stimulation of aldosterone synthesis and cell growth factors.
Retention of heterozygosity at chromosome 7p22 and 11q13 in aldosterone-producing tumours of patients with familial hyperaldosteronism not remediable by glucocorticoids
FALLO, FRANCESCO;PILON, CATIA;BARZON, LUISA;SONINO, NICOLETTA;
2004
Abstract
The mechanisms involved in aldosterone overproduction and adrenal cell proliferation of FH-II remain unknown. The genetic basis of this disorder may involve heritable alterations of more than one gene and/or reflect an unrestrained stimulation of aldosterone synthesis and cell growth factors.File in questo prodotto:
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