The case of a patient with a non-functional and poorly-differentiated adrenocortical carcinoma,who had an enexpected long-term survival after a right adrenalectomy and sebsequent removal of 2 local recurrences,is reported. However, fifteen years after the complete resection of the primary neoplasm, the patient first developed an autoimmune thrombocytopenic purpura and a later a mantle cell lymphoma located in the mediastinal lymph nodes. This case confirms the possible growth of a second tumour in patients with adrenocortical carcinoma, especially if presenting a long survival after resection of the primary malignancy, and emphasises the need for the close follow-up of these patients.
Development of mantle cell lymphoma in a patient with adrenocortical carcinoma and an 18-year survival after complete removal of the primary cancer and resection of local recurrences
ORLANDO, ROCCO;
2006
Abstract
The case of a patient with a non-functional and poorly-differentiated adrenocortical carcinoma,who had an enexpected long-term survival after a right adrenalectomy and sebsequent removal of 2 local recurrences,is reported. However, fifteen years after the complete resection of the primary neoplasm, the patient first developed an autoimmune thrombocytopenic purpura and a later a mantle cell lymphoma located in the mediastinal lymph nodes. This case confirms the possible growth of a second tumour in patients with adrenocortical carcinoma, especially if presenting a long survival after resection of the primary malignancy, and emphasises the need for the close follow-up of these patients.Pubblicazioni consigliate
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