The impact of the immunosuppressive drugs tacrolimus (FK 506) vs cyclosporine (CsA) on glucose metabolism in liver-grafted patients has, until now, not been conclusively elucidated. To date, all investigators have used oral glucose stimulation to screen glucose tolerance. But many parameters are severely deranged in liver cirrhosis, including insulin sensitivity (SI) and glucose effectiveness (SG). We investigated glucose tolerance using a modeling technique in liver-grafted patients who received immunosuppression with either CsA or FK 506.
The effect of cyclosporine vs FK 506 on glucose metabolism
TOFFOLO, GIANNA MARIA;
1999
Abstract
The impact of the immunosuppressive drugs tacrolimus (FK 506) vs cyclosporine (CsA) on glucose metabolism in liver-grafted patients has, until now, not been conclusively elucidated. To date, all investigators have used oral glucose stimulation to screen glucose tolerance. But many parameters are severely deranged in liver cirrhosis, including insulin sensitivity (SI) and glucose effectiveness (SG). We investigated glucose tolerance using a modeling technique in liver-grafted patients who received immunosuppression with either CsA or FK 506.File in questo prodotto:
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