Platelet adhesiveness and aggregation in combined factor V and factor VIII deficiency and in combined factor VII and factor VIII deficiency.

Girolami, Antonio; de Marco, L; Fabris, Fabrizio; Casonato, Sandra

Platelet aggregation and adhesiveness were studied in 3 patients with combined factor V and factor VIII deficiency and in 3 patients with combined factor VII and factor VIII deficiency. The first three patients belonged to three different kindreds whereas the second group belonged to the same kindred. Serotonin C14 uptake and release was also found to be normal in these patients. These studies indicate that platelet function is normal in combined defects of factor VIII. These findings were in agreement with the presence of a normal bleeding time and a normal factor VIII antigen level in all these patients.

Titolo:	Platelet adhesiveness and aggregation in combined factor V and factor VIII deficiency and in combined factor VII and factor VIII deficiency.
Autori:	GIROLAMI, ANTONIO de Marco L FABRIS, FABRIZIO CASONATO, SANDRA mostra contributor esterni nascondi contributor esterni
Data di pubblicazione:	1977
Rivista:	FOLIA HAEMATOLOGICA
Abstract:	Platelet aggregation and adhesiveness were studied in 3 patients with combined factor V and factor VIII deficiency and in 3 patients with combined factor VII and factor VIII deficiency. The first three patients belonged to three different kindreds whereas the second group belonged to the same kindred. Serotonin C14 uptake and release was also found to be normal in these patients. These studies indicate that platelet function is normal in combined defects of factor VIII. These findings were in agreement with the presence of a normal bleeding time and a normal factor VIII antigen level in all these patients.
Handle:	http://hdl.handle.net/11577/2489975
Appare nelle tipologie:	01.01 - Articolo in rivista

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http://hdl.handle.net/11577/2489975

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