The enzyme-multiplied immunoassay technique (EMIT) was compared with the gas-liquid chromatographic (GLC) method in the analysis of 130 urine samples from subjects receiving methadone and non-methadone controls. The GC method allowed the quantitation of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine, the major metabolite of methadone. A good correlation was found between the two methods. The advantages of using the EMIT system are discussed.
Comparison of GLC-EMIT analysis for the assay of methadon and its major metabolite in urine
FERRARA, SANTO
1979
Abstract
The enzyme-multiplied immunoassay technique (EMIT) was compared with the gas-liquid chromatographic (GLC) method in the analysis of 130 urine samples from subjects receiving methadone and non-methadone controls. The GC method allowed the quantitation of 2-ethylidene-1,5-dimethyl-3,3-diphenylpyrrolidine, the major metabolite of methadone. A good correlation was found between the two methods. The advantages of using the EMIT system are discussed.File in questo prodotto:
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