Five pregnant (two to three and one-half months) Macaca fascicularis seroconverted following immunization with sucrose-gradient purified and formalin-inactivated whole simian immunodeficiency virus (SIV(mac251)). No untoward effects on fetal maturation were observed during the immunization of the mothers. Antibodies to SIV(mac251) (also those with in vitro neutralizing activity) were passively transferred to the offspring but disappeared within two to six months after birth. Antibodies to env glycoprotein (gp130) lasted longer than those against viral gag proteins (p26,p60).
Vaccination of Pregnant Cynomolgus Monkeys With Whole Formalin-inactivated Siv(mac251)
AMADORI, ALBERTO;
1992
Abstract
Five pregnant (two to three and one-half months) Macaca fascicularis seroconverted following immunization with sucrose-gradient purified and formalin-inactivated whole simian immunodeficiency virus (SIV(mac251)). No untoward effects on fetal maturation were observed during the immunization of the mothers. Antibodies to SIV(mac251) (also those with in vitro neutralizing activity) were passively transferred to the offspring but disappeared within two to six months after birth. Antibodies to env glycoprotein (gp130) lasted longer than those against viral gag proteins (p26,p60).File in questo prodotto:
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