Two patients with hypertension due to coarctation of the aorta were treated for 12 weeks with captopril at increasing doses. After an immediate response, resistance developed to captopril, which was associated with restoration of initially elevated renin and plasma aldosterone levels. Lack of hypertension control may be related to long-term reappearance of mechanisms which lead to excessive renin stimulation. © 1985.

Resistance to captopril in hypertension of coarctation of the aorta

FALLO, FRANCESCO;MANTERO, FRANCO
1985

Abstract

Two patients with hypertension due to coarctation of the aorta were treated for 12 weeks with captopril at increasing doses. After an immediate response, resistance developed to captopril, which was associated with restoration of initially elevated renin and plasma aldosterone levels. Lack of hypertension control may be related to long-term reappearance of mechanisms which lead to excessive renin stimulation. © 1985.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11577/2503759
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