A previous study [1] on conditions affecting parameterestimation in atwocompartmentmodel is extended. In this paper the following factors and their interaction have been examined: the initial guess in the parameterspace, sampling procedures at constant time intervals, data truncations and weightingfactors in the criterion function.
Parameter estimation in a biological two compartment model. II: A computer experimental study of the influence of the initial estimate in the parameter space, of some sampling protocols and of weighting factors.
COBELLI, CLAUDIO;
1977
Abstract
A previous study [1] on conditions affecting parameterestimation in atwocompartmentmodel is extended. In this paper the following factors and their interaction have been examined: the initial guess in the parameterspace, sampling procedures at constant time intervals, data truncations and weightingfactors in the criterion function.File in questo prodotto:
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